Clinical trials: Non Invasive Ventilation (NIV)
Deep Sedation, Non-invasive Ventilation Support
Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation
In patients with high levels of fear and anxiety, it is recommended to perform dental procedures under sedation or general anesthesia depending on the nature of the procedure.
- Conditions
- Deep Sedation, Non-invasive Ventilation Support, Nasal Airway, Nasal CPAP Mask
- Trial name
- NCT06436638
- Testing
- Non-invasive ventilation support equipment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gözde Nur Erkan
Respiratory Insufficiency
Neurally Adjusted Ventilatory Assist (NAVA) in NonInvasive Ventilation (NIV)
Main hypothesis is that Neurally Adjusted Ventilatory Assist (NAVA) allows asynchrony reduction in non invasive ventilation (NIV) in comparison with reference Pressure Support (PSV) mode.
- Trial name
- NCT01426178
- Testing
- Neurally Adjusted Ventilatory Assist in Non Invasive Ventilation (Device)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Respiratory Failure
Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation
This study compare the effectiveness of dexmedetomidine as a sedative drug during NIV and the different strategies routinely used in patients with ARF of different aetiologies.
- Trial name
- DEX-PCH-VMNI (NCT02958150)
- Testing
- Dexmedetomidine, Standard Clinical Practice
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Basque Health Service
COP, Non-invasive Ventilation
Patient-ventilator Asychrony During Non-invasive Ventilation When COPD Patients Doing Exercise
Pulmonary rehabilitation programmes including aerobic exercise training have strong evidence of effectiveness in improving exercise capacity, dyspnoea and HRQL in patients with COPD.
- Conditions
- COP, Non-invasive Ventilation, Pulmonary Rehabilitation
- Trial name
- NCT04054622
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Guangzhou Medical University
Preterm, Premature
Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants
This study aimed to evaluate the effects of kinesio taping on blood gas parameters, respiratory rate, heart rate, oxygen saturation, and pressure limits in preterm infants with RDS who are on NIV.
- Conditions
- Preterm, Premature, Infant, Newborn, Diseases, Respiratory Distress Syndrome
- Trial name
- NCT06285669
- Testing
- kinesiotaping application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ondokuz Mayıs University
Respiratory Distress Syndrome (RDS) of Neonate
Non-invasive Ventilation With Neurally Adjusted Ventilatory Assist Versus Nasal Continuous Airway Pressure in Premature Infants
The purpose of this study is to compare if a new noninvasive ventilation mode (NIV NAVA) is better in noninvasive ventilation of premature infants than currently used Nasal Continuous Airway Pressure (ncpap), and if NIV NAVA…
- Trial name
- NIV NAVA (NCT01624012)
- Testing
- NIV NAVA, Nasal continuous positive airway pressure
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- University of Oulu
Chronic Obstructive Pulmonary Disease, Respiratory Failure
NHF vs NIV in Patients With Acute Exacerbation of COPD
Although non-invasive ventilation (NIV) usage has increased significantly over time in COPD exacerbation, a great percentage of patients (~30%) present contraindications to NIV or cannot tolerate it.
- Conditions
- Chronic Obstructive Pulmonary Disease, Respiratory Failure, Acute Exacerbation Copd
- Trial name
- NCT03466385
- Testing
- Nasal High Flow, Non-Invasive Ventilation
- Where
- 3 sites in Greece
- Volunteers
- 498 people
- Sponsor
- Evangelismos Hospital
COPD, Severe Early-Onset, Ventilatory Failure
Customized Masks in Non-Invasive Mechanical Ventilation
In non-invasive mechanical ventilation (NIMV), the interface is the primary determinant of success, as adherence and quality of therapy mainly depend on it.
- Conditions
- COPD, Severe Early-Onset, Ventilatory Failure, Als, Non Invasive Ventilation
- Trial name
- NCT06215391
- Testing
- 3d printed mask
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Universitario 12 de Octubre
Myotonic Dystrophy, Steinert
Factors Associated With Hypoventilation in the Myotonic Dystrophy, Progressive Profile Over 5 Years
The aim of this study is to determine the factors associated with alveolar hypoventilation in terms of cognitive impairment, daytime sleepiness, respiratory function, nocturnal respiratory events This evaluation will clarify the…
- Trial name
- Steinert (NCT03764150)
- Where
- 6 sites in France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Lille
Reperfusion Pulmonary Edema
Evaluation of the Effectiveness of Non-invasive Ventilation on the Reperfusion Pulmonary Edema Post Pulmonary Artery Angioplasty in the Post Embolic Pulmonary Hypertension
The purpose of this study is to determine whether Non Invasive Ventilation are effective in prevention of reperfusion pulmonary edema after pulmonary artery angioplasty.
- Trial name
- OPR_VNI (NCT02548091)
- Testing
- Blood samples for assays of plasma inflammatory markers (cytokines InterLeukin-6, InterLeukin-8, InterLeukin-10), Non invasive ventilation, monitoring system Pulse-Induced Contour Cardiac Output (Picco)
- Where
- France
- Volunteers
- 236 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Asthma
Non Invasive Ventilation in Acute Asthma
The aim of this study is to compare the efficacy of noninvasive positive pressure ventilation versus best medical therapy in patients with acute severe asthma
- Trial name
- NCT00510991
- Testing
- nippv
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
COPD Exacerbation Acute, COPD Exacerbation
PSV Versus ASV With Intellisync Mode for Delivery of NIV in AECOPD
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined acute worsening of respiratory symptoms requiring additional therapy.
- Trial name
- PAINT-COPD (NCT06160687)
- Testing
- PSV mode during NIV, ASV intellisync
- Where
- India
- Volunteers
- 55 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Focus of the Study is the Anatomy of the Soft Palate, Non-invasive Ventilation
The Inflate Study; Defining the Soft Palate in the Upper Airway Flow Pathway
The goal of this clinical trial is to understand the impact of the size and shape of the soft palate on gas airflow in the upper airway in healthy volunteers.
- Trial name
- NCT06738589
- Testing
- non-invasive ventilation
- Where
- New Zealand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Non-invasive Ventilation, Healthy Subjects
Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects
High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute…
- Trial name
- NCT05448417
- Testing
- Non-invasive high-frequency oscillatory ventilation, Noninvasive Bilevel Positive Pressure Ventilation
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Respiratory Failure
Optiflow in Sequential Non-Invasive Ventilation
Background : Patient with hypoxemic respiratory failure treated with NIV receive between NIV session oxygen therapy. Gaz exchange disorder with a decrease of the ratio between Partial Pressure of Arterial Oxygen (PaO2) and…
- Trial name
- VNI-HD (NCT02389166)
- Testing
- Optiflow, Conventional oxygen therapy
- Where
- 8 sites in France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Bordeaux
Cardiac Surgical Procedures, Continuous Positive Airway Pressure
Effects of Non-invasive Ventilation in Patients Undergoing Heart Surgery
The goal of this randomized controlled clinical trial is to compare effects of non-invasive ventilation with different modalities (notably CPAP and BIPAP) in patients undergoing heart surgery.
- Conditions
- Cardiac Surgical Procedures, Continuous Positive Airway Pressure, BIPAP Biphasic Intermittent Positive Airway Pressure
- Trial name
- NCT05966337
- Testing
- CPAP, BIPAP, Usual care in phisicaltherapy
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Acute Respiratory Failure
The Value of Rapid Shallow Breathing Indeks in Predicting Non-invasive Mechanical
There are some criteria such as the most frequently used parameters to predict the failure of non-invasive mechanical ventilation, the APACHE 2 score, the presence of pneumonia and ARDS in the etiology, and no improvement in one…
- Trial name
- RSBI (NCT04780503)
- Testing
- Rapid Shallow Breathing Index
- Where
- Turkey (Türkiye)
- Volunteers
- 267 people
- Sponsor
- Izmir Katip Celebi University
Hypercapnic Respiratory Failure
Clinical Trial Assessing Two Protocols to Withdraw Non-invasive Ventilation in Hypercapnic Respiratory Failure
The purpose of the study is to determine the optimal method to withdraw non-invasive ventilation after an episode of hypercapnic respiratory failure.
- Trial name
- NCT00775710
- Testing
- Nocturnal non-invasive ventilation
- Where
- 3 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Clinic of Barcelona
Acute Respiratory Distress Syndrome, Shock
Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure
The objective of our study is to evaluate the efficacy of helmet ventilation as compared with Face mask in patients with respiratory failure.
- Conditions
- Acute Respiratory Distress Syndrome, Shock, Ventilatory Failure, Cardiogenic Pulmonary Edema
- Trial name
- NCT01680783
- Testing
- Non invasive ventilation using a helmet hyperbaric device, Noninvasive ventilation via facemask
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Chicago
Airway Disease
Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy
Introduction: The non-invasive ventilation (NIV) of continuous nasopharyngeal O2 with intermittent close/open nose and abdomen compression (PO2-NC-AC) can provide effective oxygenation, ventilation and circulation.
- Trial name
- NCT03666403
- Testing
- NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan