Clinical trials: Nerve Block
Hemorrhoids, Postoperative Pain
Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain
Hemorrhoid surgery is often followed by significant pain during the first few days after the operation. Pudendal nerve block is a pain-control technique that can help reduce discomfort after surgery.
- Conditions
- Hemorrhoids, Postoperative Pain, Pudendal Nerve Block
- Trial name
- NCT07889869
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Landmark-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Laparoskopic Cholecystectomy, Recto Intercostal Nerve Block
Postoperative Analgesic Efficacy of Recto Intercostal Nerve Block
Laparoscopic cholecystectomy is a frequently performed surgery and the gold standard for the treatment of symptomatic gallstone disease.
- Trial name
- NCT07003698
- Testing
- The group without the rectointercostal nerve block, The rectointercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Total Knee Anthroplasty, Genicular Nerves Block
Efficacy of Genicular Block on Total Knee Arthroplasty Surgery
This prospective, randomized, double-blind, placebo-controlled trial evaluated the analgesic efficacy of preoperative ultrasound-guided genicular nerve block (GNB) in patients undergoing total knee arthroplasty.
- Trial name
- NCT06942702
- Testing
- Genicular blocks (bupivakain), Paracetamol (acetaminophen)+diclofenac, Patient Control Analgesia (PCA) Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Mersin University
Lower Extremity, Nerve Block
Bupivacaine-Lidocaine vs Bupivacaine for Ultrasound-Guided Popliteal Sciatic Nerve Block
This prospective, randomized, double-blind clinical trial aims to compare the efficacy of two local anesthetic regimens for ultrasound-guided popliteal sciatic nerve block in adult patients undergoing elective distal lower…
- Conditions
- Lower Extremity, Nerve Block, Pain, Postoperative, Pain, Nerve
- Trial name
- PSSNB-BL (NCT07550348)
- Testing
- Bupivacaine-Lidocaine Combination, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Nerve Block, Nerve Blocks
Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation
This randomized study will examine whether ultrasound-guided regional anaesthesia (a nerve block) contributes to new or worsening peripheral nerve problems after blast-related limb trauma.
- Conditions
- Nerve Block, Nerve Blocks, Nerve Injury, Blast Injury
- Trial name
- BRAVE (NCT07879508)
- Testing
- Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
The goal of this randomized controlled clinical trial is to determine whether adding a serratus anterior plane block (SAPB) to a pectoralis II (PECS II) block improves pain relief and reduces the need for opioids in adult women…
- Conditions
- Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection, Nerve Block; Pain Medication, Pectoralis Nerve Block
- Trial name
- PECS (NCT07881237)
- Testing
- Serratus Anterior Plane Block (SAPB) group, Pectoral nerve block (PECS)
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- Lebanese American University
Postoperative Pain, Cholecystectomy
Comparison of M-TAPA, EOIP, and Local Infiltration for Pain Relief After Laparoscopic Cholecystectomy
This retrospective observational study aimed to compare three pain management techniques used after laparoscopic gallbladder removal (cholecystectomy): modified thoracoabdominal nerve block through the perichondrial approach…
- Conditions
- Postoperative Pain, Cholecystectomy, Laparoscopic, External Oblique Intercostal Plane Block
- Trial name
- NCT07881536
- Testing
- Modified Thoracoabdominal Nerve Block Through the Perichondrial Approach, External Oblique Intercostal Plane Block, Local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Pamukkale University
Femoral Neck Fractures, Nerve Block
Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery
Femoral neck fracture surgery in elderly patients is frequently complicated by intraoperative hypotension and inadequate postoperative analgesia.
- Trial name
- NCT07346885
- Testing
- Lumbar and Sacral Plexus Block, Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Nerve Block
Effect of Injection Duration of Fascial Plane Blocks on Block Success
This prospective observational study aims to evaluate the impact of injection duration during fascial plane blocks on block success and analgesic efficacy in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07096765
- Testing
- Group O, Group T, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Knee Osteoarthritis (OA), Genicular Nerves Block
The Effect of Pulsed Radiofrequency Ablation of the Genicular Nerve on Pain, Balance, and Proprioception in Patients With Chronic Knee Osteoarthritis
Determination of the effect of ultrasound-guided pulsed radiofrequency applied to the genicular nerve on pain, balance, and proprioception in patients with chronic knee osteoarthritis
- Conditions
- Knee Osteoarthritis (OA), Genicular Nerves Block, Radiofrequency Ablation
- Trial name
- NCT07869771
- Testing
- Genicular nerve block via radiofrequency ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Combat-Related Limb Injury, Nerve Block
Nerve Blocks or Combat Trauma: What Drives Peripheral Nerve Injury?
This study will examine nerve problems after combat-related injuries to the arms or legs. Some patients receive a peripheral nerve block, an injection of local anaesthetic near a nerve, to help control pain.
- Conditions
- Combat-Related Limb Injury, Nerve Block, Nerve Damage, Nerve Blocks
- Trial name
- NERVE-COMBAT (NCT07868133)
- Volunteers
- 1,000 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Irreversible Pulpitis, Failed Inferior Alveolar Nerve Block
Articaine Versus Lidocaine for Supplemental Buccal Infiltration in Lower First Molars With Irreversible Pulpitis
Local anesthetic is used to numb a tooth before a root canal treatment. In lower back teeth with irreversible pulpitis (a painful, inflamed tooth nerve), the standard numbing injection near the jaw nerve, called an inferior…
- Trial name
- ARTLID-IP (NCT07869394)
- Testing
- Articaine 4% with epinephrine 1:100,000, Lidocaine 2% with Epinephrine 1:100,000
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rehman Medical Institute - RMI
Migraine Disorders, Medication Overuse Headache
Greater Occipital Nerve Block for Migraine With Medication Overuse Headache
Migraine is among the leading causes of disability worldwide. Inappropriate use of acute medications in the setting of primary headache, particularly migraine can result in a debilitating condition known as medication overuse…
- Conditions
- Migraine Disorders, Medication Overuse Headache, Greater Occipital Nerve Block
- Trial name
- GONB_MOH (NCT07568496)
- Testing
- Lidocaine 2% and Methylprednisolone 80 mg
- Where
- 3 sites in Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Total Knee Anthroplasty, Nerve Block
Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty
Effective postoperative pain management remains a cornerstone of enhanced recovery protocols following total knee arthroplasty (TKA).
- Conditions
- Total Knee Anthroplasty, Nerve Block, Ropivacaine, Liposomal Bupivacaine
- Trial name
- NCT07509866
- Testing
- Liposomal bupivacaine (LB), Ropivacaine with Perineural Dexamethasone, Ropivacaine with Perineural Dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
3-Needle, 5-Needle
3-Needle vs 5-Needle of Genicular Nerve Block on Pain and Quality of Life in Knee Osteoarthritis
This study aims to compare the 3-needle and 5-needle of genicular nerve block on pain and quality of life in Knee osteoarthritis (KOA).
- Conditions
- 3-Needle, 5-Needle, Genicular Nerve Block, Pain
- Trial name
- NCT07853170
- Testing
- 3-nerve-targeted group, 5-nerve-targeted group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Fractures, Hip, Local Anesthesia
Influence of Peri-operative Anesthetic and Analgesic Care on the Outcome of Patients Undergoing Hip Fracture Surgeries. A Prospective Study
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients…
- Conditions
- Fractures, Hip, Local Anesthesia, Geriatric, Nerve Block
- Trial name
- NCT06925789
- Testing
- Ropivacaine
- Sponsor
- Milton S. Hershey Medical Center
Polytrauma, Regional Anaesthesia
BLOCK-TRAUMA Study
This prospective cohort study will evaluate the association between the overall burden of regional anesthesia and early clinical outcomes in adult patients with polytrauma.
- Conditions
- Polytrauma, Regional Anaesthesia, Nerve Block, Acute Pain
- Trial name
- BLOCK-TRAUMA (NCT07702071)
- Where
- Ukraine
- Volunteers
- 500 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Rebound Pain Impact After Hip Surgery With Nerve Block
Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block
Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly.
- Trial name
- NCT07295184
- Testing
- Peripheral nerve block applied, Only multimodal analgesia applied
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konya City Hospital
Nerve Block, Regional Anesthesia
Training Non-Anesthesia Personnel to Perform Nerve Blocks in Microgravity
Space exploration is rapidly progressing with multiple upcoming missions planned to the moon and International Space Station, and projected missions to Mars in the early 2030s.
- Conditions
- Nerve Block, Regional Anesthesia, Microgravity, Space Analogue
- Trial name
- Block-aid (NCT07849049)
- Testing
- Simulated microgravity, Normal earth gravity
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Nova Scotia Health Authority
Femur Neck Fracture, Spinal Anesthesia
Comparison of Unilateral Spinal Anesthesia and Nerve Block in Hip Fractures
This randomized study aims to compare the efficacy and hemodynamic effects of hypobaric unilateral spinal anesthesia (HUSA) and lumbar plexus block (LP-SP) in patients undergoing femoral neck fracture surgery.
- Conditions
- Femur Neck Fracture, Spinal Anesthesia, Lumbar Plexus Nerve Block
- Trial name
- NCT07272226
- Testing
- Hipobaric Unilateral Spinal Anesthesia Group, Lumbar Plexus Block (LP-SP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital