Clinical trials: Neisseria Gonorrhoeae Infection
Vaginal Discharge, Sexually Transmitted Diseases
Point-of-care Tests for Vaginal Discharge in Nepal
The goal of this clinical trial is to examine if and how the implementation of point-of care-tests (POCT) for sexually transmitted infections in the management of abnormal vaginal discharge reduces the overtreatment with…
- Trial name
- POCT-BRA (NCT05977491)
- Testing
- Health care practitioner is informed of POCT results for CT and NG, Health care practitioner is informed about POCT result for TV and BV, addressing psycholsocial problems
- Where
- Nepal
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Gonorrhea Male, Chlamydia (Male)
Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM
Men who have sex with men (MSM) are at high risk for gonorrhea and chlamydia in Kenya, where nucleic acid amplification testing is not feasible and most infections therefore go undiagnosed.
- Conditions
- Gonorrhea Male, Chlamydia (Male), Syphilis Male
- Trial name
- NCT06468462
- Testing
- WHO-recommended periodic presumptive treatment, Doxycycline post-exposure prophylaxis
- Where
- 3 sites in Kenya
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy
Randomized Trial of Advanced Provision Emergency Contraception Among Women With Gonorrhea or Chlamydia
The purpose of this trial is to determine whether providing non-contracepting women with gonorrhea or chlamydial infection with advanced provision emergency contraception (APEC) and condoms decreases their risk of becoming…
- Trial name
- NCT00520455
- Testing
- levonorgestrel 0.75mg taken twice 12 hours apart (Plan B) and condoms
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Washington
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection
The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.Single-agent therapy with ceftriaxone is the preferred regimen for treatment of…
- Trial name
- NCT05216744
- Testing
- Ceftriaxone 1000mg + doxycycline 100 mg, Cefixime 800mg + doxycycline 100 mg
- Where
- Vietnam
- Volunteers
- 125 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Sexually Transmitted Diseases
Comparing Specimen Collection Techniques to Screen for Sexually Transmitted Infections in Pregnant Women: A Pilot Study
The purpose of this research study is to compare two specimen collection techniques (vaginal vs. endocervical swab) to screen for sexually transmitted infections in pregnant women.
- Trial name
- NCT03877263
- Testing
- Endocervical swab for detection of STI, Vaginal swab for detection of STI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- OhioHealth
HIV Infections, HIV Pre-Exposure Prophylaxis
Vienna HIV Infection Via Sex Study
The main objective of this prospective observational cohort study is to investigate the epidemiology, the risk factors and ultimately the incidence of novel HIV infections among individuals at high risk for acquiring HIV via sex…
- Conditions
- HIV Infections, HIV Pre-Exposure Prophylaxis, Sexually Transmitted Diseases, Gonorrhea
- Trial name
- HIVEX (NCT05326061)
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University of Vienna
Overactive Bladder Syndrome
Colonization of the Female Urethra With Mycoplasma Hominis, Ureaplasma Urealyticum, Chlamydia Trachomatis, or Neisseria Gonorrhea in Patients With Lower Urinary Tract Symptoms
The purpose of this study is to assess the prevalence of mycoplasma hominis, ureaplasma urealyticum, neisseria gonorrhea, and chlamydia trachomatis in women with overactive bladder symptoms, and to correlate these findings with…
- Trial name
- NCT01559623
- Testing
- retrospective data analysis
- Where
- Switzerland
- Volunteers
- 766 people
- Sponsor
- University of Zurich
Sexually Transmitted Diseases, Gonorrhea
Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening
In the United States (US), gay and bisexual men living with human immunodeficiency virus (HIV) bear a heavy burden of bacterial sexually transmitted infections (STIs) such as gonorrhea, chlamydia, and syphilis.
- Conditions
- Sexually Transmitted Diseases, Gonorrhea, Chlamydia, Syphilis
- Trial name
- NCT06100250
- Testing
- Motivational interviewing and specimen self-collection
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT
The purpose of this study was to use participant samples to simultaneously evaluate three nucleic acid amplification tests (NAATs) diagnostic platforms.
- Conditions
- Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection, Sexually Transmitted Infections
- Trial name
- pNAAT (NCT02870101)
- Testing
- Nucleic acid amplification test 1 for NG and CT, Nucleic acid amplification test 2 for NG and CT, Nucleic acid amplification test 3 for NG and CT
- Where
- 9 sites in United States
- Volunteers
- 2,767 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV Infection, Chlamydia
Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men
This study will estimate the rates of asymptomatic Chlamydia and/or Gonorrhea in the oropharynx, rectum and urethra (urine) of HIV infected men who have sex with men at a specialty care center and compare it to the rates in…
- Conditions
- HIV Infection, Chlamydia, Gonorrhea
- Trial name
- NCT02019771
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Nebraska
Chlamydia, Gonorrhea
Multi-center Evaluation of the VERSANT® CT/GC DNA 1.0 Assay (kPCR)in Detecting C. Trachomatis and N. Gonorrhoeae
Multicenter clinical study to test a new qualitative in vitro nucleic acid amplification assay based on kPCR technology. The assay is intended for the diagnosis of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC).
- Trial name
- NCT01167777
- Where
- 7 sites in United States
- Volunteers
- 2,296 people
- Sponsor
- Siemens Healthcare Diagnostics Inc
HIV Infections, Chlamydia Trachomatis
Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand
The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine several dimensions of acceptability.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Nesseria Gonorrhea, Trichomonas Vaginitis
- Trial name
- NCT00213057
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Population Council
Chlamydial Infection, Gonorrhoea
Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal Swabs
This is a multi-center study with a minimum of three sites in the United States. The study will enroll approximately 1750 female subjects and will have a study duration of approximately 9 months after enrollment of the first…
- Conditions
- Chlamydial Infection, Gonorrhoea, Trichomoniasis
- Trial name
- NCT03596151
- Testing
- Click Device
- Where
- 8 sites in United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Gonorrhea
Improving Clinic Delivery of HIV-related Anal Health Services
This project will test ways to reduce stigma in healthcare settings so that more providers offer, and more patients receive, important anal sex-related HIV services, including anorectal sexually transmitted infection (STI)…
- Conditions
- HIV, Gonorrhea, Chlamydia, Anal Cancer Squamous Cell
- Trial name
- PEACHES 2 (NCT07464236)
- Testing
- PEACHES 2.0 Implementation Strategies
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
GonoScreen: Efficacy of Screening STIs in MSM
A Multicentre, controlled, randomized trial of 3 site (urethra, pharynx and rectum) sampling performed every 3 months (3x3) for Neisseria gonorrhoea (Ng)/Chlamydia trachomatis (Ct) screening (comparator) vs.
- Trial name
- GonoScreen (NCT04269434)
- Testing
- No Screening
- Where
- 5 sites in Belgium
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
STI, Sexually Transmitted Infection (STI)
A Digital Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Study
This study is a pilot randomized trial of STIckER in which 40 providers (20 trained in using the STIckER decision aid and 20 providing standard care) will enroll a total of 140 sexually active young Emergency Department (ED)…
- Conditions
- STI, Sexually Transmitted Infection (STI), Sexually Transmitted Disease (STD)
- Trial name
- STIckER (NCT06014177)
- Testing
- STIckER, Control
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gonorrhea, Chlamydia
A Validation Study for Detecting Chlamydia and Gonorrhea in Rectal Samples
Our hypothesis is that nucleic acid amplification testing (NAAT) with the APTIMA Combo2 (AC2) will have greater sensitivity than culture in detecting Neisseria gonorrhoeae in rectal samples.
- Trial name
- NCT00827697
- Testing
- Gen-Probe APTIMA Combo2 (AC2)
- Where
- 2 sites in United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection
Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
The main objective of the study will be to assess the performance of the Next-Generation-Sequencing (NGS) diagnostics of Chlamydia trachomatis and Neisseria gonorrhoeae compared to reference techniques.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
- Trial name
- NGS-IST (NCT05581160)
- Testing
- Assess the Performance of Metagenomic Sequencing in the Diagnosis of STI (NGS-IST)
- Where
- 2 sites in France
- Volunteers
- 332 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Sexual Behavior, Unprotected Sex
Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention
The aim of this research protocol is to test the efficacy of a self-care intervention through a randomized controlled trial (RCT), for increasing protective sexual health behaviors among youth in the participating Native American…
- Conditions
- Sexual Behavior, Unprotected Sex, Gonorrhea, Chlamydia
- Trial name
- NCT03895320
- Testing
- Sexual Health Risk Assessment, Sexual Health Score, Sexual Health Messaging
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Bacterial Vaginosis, Vaginal Microbiome
Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs
HIV remains a global pandemic with 37 million infected. In western Kenya, 16% of women in the general population and 29% of the poorest women have HIV.
- Conditions
- Bacterial Vaginosis, Vaginal Microbiome, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
- Trial name
- POWWERHealth (NCT05666778)
- Testing
- Menstrual Cup
- Where
- 2 sites in United States, Kenya
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center