Clinical trials: Near Vision
Myopia
In-vivo Wettability Grading and Assessment Study
The purpose of this study is to investigate the front surface wettability of soft contact lenses while on eye.
- Trial name
- CIAN (NCT01010555)
- Testing
- lotrafilcon B, balafilcon A, senofilcon A
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- CIBA VISION
Hypothyroidism
Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation
The purpose of this study is to investigate the effect of switching participants taking levothyroxine to a new sodium formulation.
- Trial name
- NCT01916304
- Testing
- Levothyroxine sodium new formulation
- Where
- Belgium
- Volunteers
- 101 people
- Sponsor
- Takeda
Nociceptive Pain, Musculoskeletal Pain
Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain
This is a trial to measure the effectiveness and safety of the invisa-RED® IR REHAB device. The researchers will compare the muscle and joint pain relief of participants who are treated with the real machine, to those treated…
- Trial name
- NCT06393088
- Testing
- IR REHAB
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- IR Technology, LLC
Myopia, Refractive Error
A Comparison of Two Color Contact Lenses in Habitual Clear Contact Lens Wearers
The purpose of this study was to evaluate overall satisfaction with AIR OPTIX® COLORS as compared to FRESHLOOK® COLORBLENDS contact lenses.
- Trial name
- NCT01782482
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 574 people
- Sponsor
- Alcon Research
Parathyroid Adenoma, Parathyroid Neoplasms
Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Parathyroid Adenoma, Parathyroid Neoplasms, Parathyroid Hyperplasia, Parathyroid Cancer
- Trial name
- NIRAF (NCT04299425)
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Vascular Access
Comparison of Different Techniques on First Attempt Success in Difficult Vascular Access Patients
The aim of this study is to investigate whether there is any difference between the use of standard techniques, ultrasonography and infra-red light for the success of the first attempt in difficult peripheral vascular access…
- Trial name
- NCT04821362
- Testing
- Ultrasound group, Near Infrared Device Group
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Ege University
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Cataract
Evaluation of 3 Intraocular Lenses Following Lens Extraction
The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.
- Trial name
- NCT01122576
- Testing
- Crystalens AO, ReSTOR, Tecnis Multifocal IOL
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Bausch & Lomb Incorporated
Neurodevelopmental Abnormality
Umbilical Cord Milking in Non-Vigorous Infants Developmental Followup (MINVIFU)
A sub-study to evaluate longer-term developmental outcomes in non-vigorous term and near-term newborns who receive umbilical cord milking in comparison to those who undergo early cord clamping at delivery.
- Trial name
- MINVIFU (NCT03621943)
- Testing
- Umbilical Cord Milking, Early Cord Clamping
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,207 people
- Sponsor
- Sharp HealthCare
Laparoscopic/Minimally Invasive Colorectal Surgery
A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery
The primary purpose of this study was to determine the optimal dose of ASP5354 for ureter visualization in participants undergoing laparoscopic/minimally invasive colorectal surgery This study also investigated the safety…
- Trial name
- NCT04238481
- Testing
- Pudexacianinium chloride
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Astellas Pharma Inc
Refractive Errors, Myopia
Clinical Assessment of a HYDRAGLYDE® Regimen
The purpose of this study is to evaluate worn AIR OPTIX® plus HYDRAGLYDE® (AOHG) lenses cleaned and disinfected with HYDRAGLYDE® containing lens solutions compared to each of the control habitual silicone hydrogel (SiHy) lenses…
- Conditions
- Refractive Errors, Myopia, Hypermetropia
- Trial name
- NCT03026257
- Testing
- Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent
- Where
- 8 sites in United States, Canada and 1 more
- Volunteers
- 323 people
- Sponsor
- Alcon, a Novartis Company
Myopia
The Clinical Comparison of Narafilcon A and Stenfilcon A Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the narafilcon A lens with the stenfilcon A lens when used on a daily wear, daily disposable basis.
- Trial name
- NCT02920970
- Testing
- narafilcon A, stenfilcon A
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors
Bifocal & Atropine in Myopia (BAM) Study
This study will test whether the combined treatment of 0.01% atropine and soft bifocal contact lens wear produces slower myopia progression and axial elongation compared to soft bifocal contact lenses alone in children ages 7 to…
- Trial name
- BAM (NCT03312257)
- Testing
- Multifocal D +2.50 add & 0.01% atropine
- Volunteers
- 49 people
- Sponsor
- Jenny Jones
Healthy, Brain Stimulation
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
- Conditions
- Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition
- Trial name
- BRAIN-STIM (NCT06995560)
- Testing
- Active Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of Stenfilcon A Versus Etafilcon A
Evaluation of two contact lenses
- Trial name
- NCT01809834
- Testing
- Etafilcon A, Stenfilcon A
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Study of Approved Contact Lenses
Evaluation of Johnson \& Johnson Acuvue Vita (senofilcon C) soft contact lenses to the Bausch + Lomb Ultra (samfilcon A) soft contact lenses
- Trial name
- NCT03351101
- Testing
- Senofilcon C, Samfilcon A
- Where
- 11 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Evaluation of Deposits on Contact Lenses Worn Extended Wear
The purpose of this study was to measure lipid deposits on commercially marketed contact lenses when worn on an extended wear (overnight) basis for 7 days.
- Trial name
- NCT00725530
- Testing
- balafilcon A contact lens (PureVision), etafilcon A contact lens (Acuvue2)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research