Clinical trials: Natural Killer Cell Mediated Immunity
Natural Killer Cell Mediated Immunity
Natural Killer Cells Reconstitution Kinetics Post Haploidentical Transplantation
Patients undergoing haploidentical allo-HSCT will be prospectively enrolled exploring the NK cells phenotype and functional reconstitution.
- Trial name
- NCT02978274
- Testing
- MMF
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
NK Cell Mediated Immunity, Endometriosis
Clinical Study of NK Cells in the Treatment of Severe Endometriosis
Dysfunction of natural koller cells (NK cells) is an important factor in the development of endometriosis. NK cell therapy was applied to treat severe endometriosis, which is an exploration of the pathogenesis of this refractory…
- Trial name
- NCT03948828
- Testing
- Autologous NK cell therapy, GnRHa combained with reverse addition therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenzhen People's Hospital
Colorectal Cancer, Surgery
Human Blood Specimen Collection to Evaluate Immune Cell Function
Natural killer (NK) cells are leukocytes of the innate immune system and play a central role in the control of cancer metastases.
- Conditions
- Colorectal Cancer, Surgery, Perioperative Care
- Trial name
- NCT03422120
- Testing
- Natural Killer Cell Activity Assay
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Primary Graft Dysfunction, Lung Transplantation
This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction
Lung transplant recipient survival lags other solid organ recipients, with the main early cause of death being primary graft dysfunction (PGD).
- Conditions
- Primary Graft Dysfunction, Lung Transplantation, Acute Lung Injury(ALI), Natural Killer Cell Mediated Immunity
- Trial name
- MARAVIROC (NCT06853223)
- Testing
- Maraviroc
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
NK Cell Mediated Immunity
Effect of NK Cell Immunotherapy on Advanced Lung Adenocarcinoma Adenocarcinoma With EGFR Mutation
This study was attempted to investigate the efficiency of NK cells immunotherapy on non-small cell lung cancer with and without EGFR mutation, and evaluated response rate (RR) and the progression-free survival (PFS).
- Trial name
- NCT03662477
- Testing
- NK cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shenzhen Fifth People's Hospital
NK Cell Mediated Immunity, NK Cell Cytokine Production
Cellular Immunity and Renal Cell Cancer
Renal cell cancer (RCC) is one of the most important urogenital tumors because of it's high mortality and increasing incidence. RCC, which accounts about 3% of all malignant tumors in the adults, is the most lethal urogenital…
- Conditions
- NK Cell Mediated Immunity, NK Cell Cytokine Production, Kidney Cancer
- Trial name
- NCT04377113
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka
Advanced Cancer, ADCC
Immunotherapy of Advanced Cancer Using a Combination Nimotuzumab and NK Cells
NK cells can persist and expand in vivo following adoptive transfer and may have a role in the treatment of late stage malignancies.
- Conditions
- Advanced Cancer, ADCC, NK Cell Mediated Immunity, Nimotuzumab
- Trial name
- NCT03554889
- Testing
- NK Cell adaptive transfer, Nimotuzumab
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Hangzhou Cancer Hospital