Clinical trials: Myopia; Refractive Error
Myopia, Astigmatism
Z8 OCT-controlled 2D vs 3D LASIK
The aim of this study was to test the hypothesis that OCT-guided 110 µm targeted flaps will result in accurate, predictable, and precise thickness flaps, with low complication rates when performed and compared using both 2D and…
- Trial name
- NCT04426175
- Testing
- 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Zentrumsehstarke Hamburg
Refractive Error
Clinical Assessment of DAILIES TOTAL1® (DT1) Multifocal
The purpose of this study is to evaluate DAILIES TOTAL1® Multifocal (DTl MF) contact lenses in current multifocal contact lens wearers with symptoms of end of day discomfort compared to their habitual multifocal contact lens…
- Trial name
- NCT02871375
- Testing
- Delefilcon A multifocal contact lenses, Habitual multifocal contact lenses
- Volunteers
- 170 people
- Sponsor
- Alcon, a Novartis Company
Myopia
Clinical Evaluation of the Safety and Efficacy of Yung Sheng 55 % Color Contact Lens
This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 55% Color Contact Lens for vision correction.
- Trial name
- NCT06128486
- Testing
- Soft Contact Lens
- Volunteers
- 62 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia, Hyperopia
Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers
The purpose of this study was to compare the clinical performance of two different reusable lenses in habitual spherical soft lens wearers.
- Trial name
- NCT06098339
- Testing
- Lens A (fanfilcon A), Lens B (lotrafilcon B)
- Where
- 3 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
The purpose of this study is to compare two marketed contact lens care solutions in regards to comfort and ocular health.
- Trial name
- NCT00813761
- Testing
- O2Optix contact lens, Proclear contact lens, ReNu MultiPlus Multi-Purpose Solution
- Where
- 26 sites in United States, United Kingdom
- Volunteers
- 473 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Myopia
Intrastromal Correction of Ametropia by a Femtosecond Laser
This study evaluates the intrastromal correction of ametropia with a femtosecond laser made by 20/10 PERFECT VISION. This laser generates a beam of ultrashort, infrared pulses which enables very precise cuts in the cornea.
- Conditions
- Presbyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- ISCAF (NCT00928122)
- Testing
- Intrastromal Correction of Presbyopia, Intrastromal correction of Myopia, Intrastromal Correction of Hyperopia
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- 20/10 Perfect Vision
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
A Dispensing Clinical Trial of a Study Test Silicone Hydrogel Lens Against Control Lens Over 1 Week
This is a 1-week dispensing, double-masked, randomized, bilateral study comparing the test lens against the control lens.
- Trial name
- NCT02500368
- Testing
- silicone hydrogel lens (test), enfilcon A lens (control)
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Myopia
A Study to Evaluate the Product Performance of the PureVision®2 High Definition (HD) Contact Lens
The objective of this study is to evaluate the product performance of PureVision2 HD contact lenses.
- Trial name
- NCT01416142
- Testing
- PureVision2 HD contact lenses, Spectacles
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Pathological Myopia
Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
This study is designed to evaluate the efficacy and safety of two different dosing regimens of 0.5 mg ranibizumab given as intravitreal injection in comparison to verteporfin PDT in patients with visual impairment due to…
- Trial name
- NCT01217944
- Testing
- Ranibizumab, Verteporfin PDT
- Where
- 74 sites in Austria, Canada and 18 more
- Volunteers
- 277 people
- Sponsor
- Novartis Pharmaceuticals
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Myopia
Exploratory Study on the Effect of SAT-001 on Choroidal Thickness in Pediatric Myopia Patients
This clinical trial aims to exploratively compare and evaluate the structural changes in the eye (specifically changes in choroidal thickness) pre- and post-treatment of the investigational medical devices ('SAT-001' and…
- Trial name
- NCT06729723
- Testing
- SAT-001, modified SAT-001
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S-Alpha Therapeutics, Inc.
Myopia
Comparative Performance of PureVision Lens Designs
The objective of this study is to evaluate the performance of the PureVision Lens designs when worn on a 30-day continuous wear basis
- Trial name
- NCT00661687
- Testing
- Currently Marketed PureVision Contact Lens., Alternate Design of the PureVision Contact Lens.
- Where
- 2 sites in Malaysia, Philippines
- Volunteers
- 206 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients
The objective of this study is to obtain an additional 36 months of safety and effectiveness data from all subjects who were implanted with the VisAbility™ Micro Insert in the VIS-2014 clinical trial.
- Trial name
- NCT03811249
- Testing
- VisAbility™ Micro Insert
- Where
- 13 sites in United States
- Volunteers
- 287 people
- Sponsor
- VisDura, Inc.
Myopia, Astigmatism
A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System
The purpose of this study is to evaluate the safety and effectiveness of the ALLEGRETTO WAVE EYE-Q excimer laser system for the reduction of myopia with or without astigmatism in subjects undergoing photorefractive keratectomy…
- Trial name
- NCT01699087
- Testing
- Photorefractive keratectomy (PRK), ALLEGRETTO WAVE EYE-Q excimer laser system
- Volunteers
- 176 people
- Sponsor
- Alcon Research
Myopia
Clinical Trial Protocol for Safety and Efficacy of Soft Contact Lens
This project is a multi-center, randomized, parallel-controlled, non-inferior clinical trial of soft contact lenses.
- Trial name
- NCT04299243
- Testing
- Contact Lenses
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia
Safety and Efficacy of T10430 Eye Drops in Controlling Paediatric Myopia Progression
Axial myopia is a type of nearsightedness that happens when the eye is too long from front to back. This causes distant vision to be blurry.
- Trial name
- NCT07522242
- Testing
- T10430 lower dose, T10430 middle dose, T10430 higher dose
- Where
- 10 sites in Jordan, South Africa and 1 more
- Volunteers
- 200 people
- Sponsor
- Laboratoires Thea