Clinical trials: Myopia; Refractive Error
Refractive Error - Myopia Severe, Refractive Error - Myopia Simple
Early Feasibility Study of UV-Femtosecond Laser Assisted Lenticular Extraction
The purpose of this study is to evaluate the initial safety of the UV-FS laser in humans.
- Trial name
- NCT03021707
- Testing
- WaveLight® Ultraviolet Femtosecond (FS) Laser System, Laser Assisted Lenticular Extraction
- Where
- 4 sites in United States, Ireland and 1 more
- Volunteers
- 7 people
- Sponsor
- Alcon Research
Myopia
Myopia Control Efficacy of Second-generation DIMS Spectacle Lenses on Fast Progressing Myopes
The purpose of this study is to examine the efficacy and performance of the variant of Defocus Incorporated Spectacle lenses on controlling myopia progression in fast progressing myopic children.
- Trial name
- NCT05888792
- Testing
- Variant of Defocus Incorporated Spectacle lens (DG2)
- Where
- Hong Kong
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Topography-Guided Customized PRK Versus Q-value Adjusted PRK in Correction of Myopia With or Without Astigmatism
This study will include patients who will undergo PRK in both eyes, for each patient each eye will be randomly allocated to one of 2 procedures: topography-guided ablation in one eye (group I) and Q-factor customized ablation in…
- Trial name
- NCT03291873
- Testing
- PRK
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Kasr El Aini Hospital
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Myopia Progression
Contact Lenses to Slow Myopia Progression in Adults
Myopia (nearsightedness) can continue to worsen during young adulthood, increasing the risk of sight-threatening eye diseases later in life.
- Trial name
- NCT07747311
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of California, Berkeley
Myopia
Wavefront-guided LASIK for Correction of Myopia
Laser in situ keratomileusis is a successful procedure for the treatment of low to moderate myopia. Advances over the last decade have allowed LASIK to also correct higher order wavefront aberrations.
- Trial name
- NCT01682434
- Testing
- Laser in situ keratomileusis (LASIK)
- Where
- Denmark
- Sponsor
- Aarhus University Hospital
Myopia
To Study the Effects of Cordyceps Cicadae on Vision Care
Cordyceps cicadae is a traditional Asian herbal medicine with a variety of bioactive substances and curative effects similar to Cordyceps Cicadae, and it has been reported that anti-dry eye and eye protection ingredients can be…
- Trial name
- NCT05778409
- Testing
- Cordyceps cicadae extract
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops
To assess the one-month ocular effects of nightly application of experimental BHVI2 and 0.02% atropine eye drops either alone or in combination, in children aged between 6 to 13 years old with myopia and randomized to use of…
- Trial name
- NCT03690414
- Testing
- Experimental BHVI2, Atropine sulfate 0.02% eye drops, Combination eye drops
- Where
- Vietnam
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Myopia, Cornea
Euclid Phoenix Lens Design Trial
The "first fit" success rate of the current Euclid orthokeratology "MAX" lens design will be compared to that of the new Euclid orthokeratology MAX "Phoenix" lens design in 30 children.
- Trial name
- NCT06389916
- Testing
- Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Vistakon Investigational Lens Worn as a Single Use Daily Wear
This study is intended to show that the investigational contact lens is clinically equivalent to a currently approved contact lens, when worn as single-use on a daily basis.
- Trial name
- NCT01031004
- Testing
- narafilcon B, etafilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Investigation of the Regulation of Retinal and Choroidal Blood Vessels in Various AL Based on WF SS-OCTA Detection With Changes in Body Position
This prospective observational study aims to understand the effects of different subaxial body positions on choroidal and retinal blood vessel density.
- Trial name
- NCT06587776
- Volunteers
- 60 people
- Sponsor
- Science and Technology Department of Sichuan Province
Myopia
Noninvasive and Dynamic Monitoring the Biological Parameters of Eyes in Different Age Groups
Myopia is the most common refractive eye disease worldwide. The number of cases is up to 2 billion. In recent years, the incidence of myopia in China is obviously rising trend.
- Trial name
- NCT05250440
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Myopia Progressing
3D Designed Defocus Lenses on Myopia Control in Children and Adolescents
This study aims to evaluate the effectiveness of lenses with 3D Designed Defocus in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective design, and apply personalized…
- Trial name
- NCT07284147
- Testing
- Defocus Lenses
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
A Clinical Assessment of the Hemacopolymer Daily Disposable Limbal Ring Soft Contact Lens
This purpose of this study is to compare the clinical performance and subjective acceptance of two different daily disposable limbal ring lenses.
- Trial name
- NCT01965262
- Testing
- Hema-copolymer Lens, etafilcon A Lens
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Myopia
Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial
The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly…
- Trial name
- DONUT (NCT07567040)
- Testing
- Atropine Sulfate 0.05% Oph Soln
- Where
- 13 sites in United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Astigmatism
On-Eye Evaluation of Contact Lens Axis Location
The purpose of this study was to evaluate the axis location of toric contact lenses after 3 minutes of wear. During this 1-visit study, each participant wore 3 pairs of study lenses of various design iterations (2-87-1, 2-87-2…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT02100410
- Testing
- Delefilcon A toric contact lens T1, Delefilcon A toric contact lens T2, Delefilcon A toric contact lens T3
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of an Investigational Soft Contact Lens
The purpose of this 4-week dispensing trial is to evaluate and compare an investigational soft contact lens worn on a daily disposable basis with three other soft contact lenses also worn on a daily disposable basis.
- Trial name
- NCT01254747
- Testing
- Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus)
- Where
- 2 sites in United States, Germany
- Volunteers
- 130 people
- Sponsor
- CIBA VISION
Astigmatism, High Myopia
Comparison Between TICL and ICL+AK for High Myopic Astigmatism
To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.
- Trial name
- NCT03202485
- Testing
- Toric Implantable Collamer Lens, ICL + Astigmatic keratotomy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
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