Clinical trials: Myocardial Revascularization
Coronary Artery Disease, Coronary Artery Bypass Grafting
Extensive BITA Grafting in the Canary Islands: an IPTW Analysis
Coronary artery bypass grafting (CABG) remains the preferred revascularization strategy for patients with complex multivessel coronary artery disease.
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Myocardial Revascularization
- Trial name
- BITA-SURV (NCT07796750)
- Where
- Spain
- Volunteers
- 666 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Percutaneous Coronary Intervention, Myocardial Revascularization
Clinical Study of Chinese Herbal Compound Qidan Xiaoke Granules in Patients After Coronary Revascularization
1. Evaluate the efficacy and safety of Qidan Xiaohe granules in patients after coronary revascularization surgery; 2. Develop a traditional Chinese medicine rehabilitation treatment plan and evaluation system for the use of Qidan…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Revascularization, Coronary Artery Disease
- Trial name
- NCT07616544
- Testing
- Qidan Xiaoke Granules + Standard Medical Therapy
- Volunteers
- 164 people
- Sponsor
- Liu Qiang
Coronary Artery Disease, Postoperative Period
Establishment of Disease Characteristics and a Chinese Medicine Prognosis Risk Model Based on a Large-Scale Database After Coronary Revascularization
This study aims to develop a risk prediction model for patients who have undergone coronary revascularization (such as stent placement or bypass surgery).
- Conditions
- Coronary Artery Disease, Postoperative Period, Myocardial Revascularization
- Trial name
- NCT07613060
- Volunteers
- 600 people
- Sponsor
- Liu Qiang
Percutaneous Coronary Intervention, Myocardial Revascularization
Baduanjin Intervention in Clinical Studies After Coronary Revascularization Surgery
1. To evaluate the efficacy and safety of the Baduanjin exercise programme in patients following coronary revascularisation surgery; 2.
- Conditions
- Percutaneous Coronary Intervention, Myocardial Revascularization, Coronary Artery Disease
- Trial name
- NCT07607951
- Testing
- Standardized Western medical treatment + Standardized Baduanjin rehabilitation training, Standardized Western medical treatment + Aerobic exercise training
- Volunteers
- 310 people
- Sponsor
- Liu Qiang
Coronary Artery Disease, Myocardial Revascularization
Nursing Intervention for Adaptation After Myocardial Revascularization
Introduction: Myocardial revascularization is an essential procedure for patients with cardiovascular disease. Its recovery in the outpatient setting involves significant challenges for both the patient and the caregiver.
- Conditions
- Coronary Artery Disease, Myocardial Revascularization, Postoperative Recovery After Cardiac Surgery, Nursing Care
- Trial name
- ADAPT-CABG (NCT07576569)
- Testing
- Nursing Intervention Program, Usual Care
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Universidad de la Sabana
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Heart Attack, Revascularization
A Prospective Randomized Trial of External Vein Graft Support in Surgical Myocardial Revascularization
The aim of the thesis is to compare a group of patients using vein grafts with and without external support, specifically their patency.
- Trial name
- Vest II (NCT06629701)
- Testing
- External support for vein grafts
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Pilsen
Coronary Artery Disease, Coronary Artery Disease Progression
Disease Characteristics of R-CAD
The present case-control study is designed to investigate the disease characteristics of rapidly progressive coronary artery disease (R-CAD) by comparing the demographics, clinical features, lab results, imaging findings, and…
- Conditions
- Coronary Artery Disease, Coronary Artery Disease Progression, Coronary Stenosis, Coronary Restenosis
- Trial name
- NCT07239921
- Testing
- Protocol-defined Examinations and Evaluations
- Volunteers
- 52 people
- Sponsor
- Peking Union Medical College Hospital
Myocardial Infarction, Coronary Revascularization
Transfusion Trigger After Operations in High Cardiac Risk Patients
The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is…
- Conditions
- Myocardial Infarction, Coronary Revascularization, Acute Renal Failure
- Trial name
- TOP (NCT03229941)
- Testing
- Blood Transfusion
- Where
- 16 sites in United States
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiopulmonary Bypass Surgery, Aortic Valve Surgery
Methylene Blue-Enhanced Ultrafiltration Improves Outcomes After Cardiopulmonary Bypass
Introduction: Fluid overload and systemic inflammation are major contributors to postoperative complications in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB).
- Conditions
- Cardiopulmonary Bypass Surgery, Aortic Valve Surgery, Mitral Valve Surgery, Myocardial Revascularization Surgery With Extracorporeal Circulation
- Trial name
- NCT07212842
- Testing
- Methylene Blue, Conventional ultrafiltration, Zero-balance ultrafiltration
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- University of Sao Paulo
Cardiovascular Disease, Myocardial Infarction
EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial…
- Conditions
- Cardiovascular Disease, Myocardial Infarction, Stroke, Coronary Revascularization
- Trial name
- EVOLVE-MI (NCT05284747)
- Testing
- Evolocumab, Routine Lipid Management
- Where
- 120 sites in United States, Brazil and 1 more
- Volunteers
- 6,019 people
- Sponsor
- Amgen
Multivessel Coronary Artery Disease, Vessel Disease
Functional Testing Underlying Coronary Revascularisation
The objective of this trial is to compare the clinical outcomes and cost-effectiveness of 2 therapeutic strategies, one based on coronary angiography guidance and the other based on coronary angiography with fractional flow…
- Conditions
- Multivessel Coronary Artery Disease, Vessel Disease, Stable Angina, Unstable Angina or Stabilized Non-ST Elevated Myocardial Infarction
- Trial name
- FUTURE (NCT01881555)
- Testing
- invasive coronary angiography, Functional testing by fractional flow reserve measurement
- Where
- France
- Volunteers
- 941 people
- Sponsor
- Hospices Civils de Lyon
Acute Myocardial Infarction, STEMI
Evaluation in STEMI Patients Using FDY-5301
To assess the effect of FDY-5301 on cardiovascular mortality and acute heart failure events in subjects with an anterior STEMI undergoing pPCI.
- Conditions
- Acute Myocardial Infarction, STEMI, Percutaneous Coronary Revascularization
- Trial name
- IOCYTE AMI-3 (NCT04837001)
- Testing
- FDY-5301
- Where
- 52 sites in United States, Canada and 4 more
- Volunteers
- 2,351 people
- Sponsor
- Faraday Pharmaceuticals, Inc.
Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI
FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease
To compare FFR guided complete revascularization during the index procedure with usual care in non-STEMI patients with multivessel disease.
- Conditions
- Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization
- Trial name
- SLIM (NCT03562572)
- Testing
- Ischemia driven revascularization, Usual care group
- Where
- 9 sites in Czechia, Hungary and 1 more
- Volunteers
- 476 people
- Sponsor
- Zuyderland Medisch Centrum
Myocardial Revascularization Surgery With Extracorporeal Circulation
Retinal Microvascular Network and Coronary Revascularization Surgery at the Dijon University Hospital
When coronary artery disease cannot be treated with medication, revascularization surgery can be performed. Although there have been many advances in recent years, this surgery is still associated with a high incidence of…
- Trial name
- MRCC (NCT05315349)
- Testing
- Complete ophthalmological check-up, Blood sampling
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Myocardial Infarction, Ischemic Stroke
Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)
The aim of this study is to assess how long-term alcohol consumption influences health risks by emulating the Moderate Alcohol and Cardiovascular Health Trial (MACH15).
- Conditions
- Myocardial Infarction, Ischemic Stroke, Angina Pectoris, Coronary Revascularization
- Trial name
- NCT06583161
- Testing
- Moderate drinking, Quitting, Social drinking
- Volunteers
- 503,325 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Acute Myocardial Infarction, Revascularization
Long Term Predictors of Acute Myocardial Infarction in Patients With Coronary Revascularization
Worldwide, Ischemic heart disease is the single most common fatal disease. One of the most common causes of acute myocardial infarction is represented by obesity.
- Trial name
- NCT06546228
- Testing
- No intervention. Only observational.
- Where
- Italy
- Volunteers
- 652 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Myocardial Ischemia, Coronary Artery Bypass Grafting
The Effects of Allicor on Patients After Coronary Arteria Revascularization Treatment
Coronary revascularization interventions such as coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are the standard of surgical treatment of patients with myocardial ischemia.
- Conditions
- Myocardial Ischemia, Coronary Artery Bypass Grafting, Coronary Arteriosclerosis, Percutaneous Coronary Revascularization
- Trial name
- TEA-CART (NCT05803759)
- Testing
- Allicor
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Institute for Atherosclerosis Research, Russia
Cardiovascular Death, Myocardial Infarction
BioFreedom™ BA9™ Ultra
The purpose of the study is to assess the safety and efficacy of the BioFreedom Ultra stent for treatment of STEMI patients. Besides, in patients who are clinically indicated for a stage procedure, Investigators aim to assess the…
- Conditions
- Cardiovascular Death, Myocardial Infarction, Revascularization
- Trial name
- NCT05331547
- Testing
- BioFreedom BA9 (SS) Ultra DCS
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong