Clinical trials: Muscle Damage
Ozone Therapy, Muscle Damage
Effects of Ozone Therapy on Muscle Damage
The goal of this clinical trial is to determine the effectiveness of different ozone therapy methods in enhancing recovery after muscle-damaging exercise in healthy adults, and to evaluate their impact on biochemical markers of…
- Conditions
- Ozone Therapy, Muscle Damage, Oxidative Stress, Recovery
- Trial name
- NCT07728422
- Testing
- Autohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Inonu University
Cerebral Palsy, Spastic
Muscle-tendon Pathology and Metabolic Dysregulation in CP
The main aim of this project is to gain knowledge about the muscle-tendon pathology of moderately to severely affected young people with cerebral palsy and their risk for cardiometabolic diseases and chronic inflammation.
- Trial name
- NCT06330922
- Testing
- Cardiorespiratory fitness training
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Graz
Cerebral Palsy, Spastic
Whole Body Vibration in Children With Cerebral Palsy
Some positive effects of whole body vibration applications in reducing spasticity, improving walking ability, and increasing walking speed have been reported in children with CP, but the evidence is not strong enough.
- Trial name
- CP (NCT05636241)
- Testing
- conventional physiotherapy program, whole body vibration training program
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Kutahya Health Sciences University
Cerebral Palsy
Effect of TENS in Children With Spastic Cerebral Palsy
TENS is cheap and simple tool for physiotherapist, free of many side effects compared with other tools. so The aim of study was record the effect of TENS on calf muscle tone in spastic cerebral palsy children.
- Trial name
- NCT05649254
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Cerebral Palsy
3-meter Walk Back Test, Proprioception, Trunk Control and Muscle Strength in Children With Cerebral Palsy
The gait problems of the child with CP should be examined in detail. At this point, by assigning a different task to the child with the backward walking assessment, body perception, trunk stability provided by anterior-posterior…
- Trial name
- NCT05088629
- Testing
- Clinical Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sanko University
Exercise, Ultra-endurance Running
Effect of Exogenous Ketosis During Ultra-endurance Exercise
The aim of this study is to investigate the effect of oral ketone administration during and immediately after an ultramarathon. Potential changes in cognitive function (reaction time, number of errors), running performance, jump…
- Conditions
- Exercise, Ultra-endurance Running, Ketosis, Skeletal Muscle
- Trial name
- NCT05407753
- Testing
- Ketone ester
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cerebral Palsy
Plyometric Exercise-induced Mechano-morphological Changes of Plantar Flexor Muscle-tendon Unit in Cerebral Palsy
This study was designed to investigate the effect of three months of plyometric exercise training on the mechanical and morphological properties of the plantar flexor muscle-tendon unit in children with unilateral cerebral palsy…
- Trial name
- NCT05301738
- Testing
- Plyometric Exercises, Standard Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Cairo University
Spastic Cerebral Palsy
INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT)
Prospective, open-label, non-randomized, single-arm, dose titration, phase II study. The study will consist of three injection cycles. In each, an injection visit is followed by an observation period of 12 to 20 weeks.
- Trial name
- INCIPIT (NCT05340439)
- Testing
- IncobotulinumtoxinA 100 UNT [Xeomin]
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Cerebral Palsy
Short-Burst Interval Treadmill Training Cerebral Palsy
Ambulatory children with cerebral palsy (CP) walk predominately in low intensity stride rates with little variability, thus limiting their walking activity and ability to participate in daily life.
- Trial name
- NCT04026295
- Testing
- Short Burst Interval Treadmill Training (SBLTT), Traditional Locomotor Treadmill Training (TLTT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kristie Bjornson
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Spasticity/Paresis, Cerebral Palsy
Efficacy of Extracorporeal Shock Wave Therapy in Children With Cerebral Palsy
Spastic plantar and palmar flexion deformities are very common in children with cerebral palsy (CP). These deformities usually involve spasticity of the plantar or palmar muscle complexes, weakness of the antagonist dorsiflexor…
- Trial name
- NCT06128616
- Testing
- ESWT, Botulinum Toxin Type A, Serial Casting
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Cerebral Palsy, Cerebral Palsy, Mixed
10-week Leucine Supplementation in Cerebral Palsy
The purpose of this study is to assess the effects of 10-weeks leucine supplementation on muscle growth, metabolism, body composition, inflammation and wellbeing in adolescents and young adults with CP.
- Conditions
- Cerebral Palsy, Cerebral Palsy, Mixed, Cerebral Palsy Ataxic
- Trial name
- NCT03668548
- Testing
- Leucine
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- St Mary's University College
Skeletal Muscle Damage
Recovery Kinetics Following Change of Direction Training
This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single change of direction (COD) training session in competitive soccer players.
- Trial name
- NCT04795232
- Testing
- COD45, COD90
- Where
- 2 sites in Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Cerebral Palsy
Ankle-foot Orthoses for Night Splinting in Children With CP: Impact on Passive Stiffness in Plantarflexors Muscles
Children with cerebral palsy present early in the childhood altered muscular properties, characterized by short muscle belly length and increased stiffness which contribute to contracture and limiting joint range of motion.
- Trial name
- NIGHTSTRETCH (NCT03686644)
- Testing
- Wearing of night splint ankle foot orthoses (phase A), No wearing of night splint ankle foot orthoses (phase B)
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spastic Cerebral Palsy
Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy
This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor…
- Trial name
- NCT05126693
- Testing
- Botulinum Toxin treatment combined with a post-BoNT intensive physical therapy period guided by individualized treatment goals.
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Phase Angle
Phase Angle as a Marker of Muscle Damage, Muscle Fatigue and Inflammation, After Eccentric Exercise
The purpose of this study will be to assess the effectiveness of bioimpedance device (BIA) as a safe, rapid, and non-invasive method of analyzing muscle damage induced by high intensity induced eccentric exercise as an…
- Trial name
- NCT05583500
- Testing
- Experimental: Single group: excentric exercise protocol
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Muscle Soreness, Pain
Recovery and Muscle Function After Supplementation With Turmeric
The objective of the study is to test the capacity of a five-day supplementation of Turmipure Gold® to improve exercise-induced muscle pain and function recovery in moderately active adults after exercise-induced muscle damage
- Conditions
- Muscle Soreness, Pain, Muscle Damage
- Trial name
- RECOFAST (NCT04946981)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Cerebral Palsy, Temporomandibular Disorder (TMD)
TMJ Dysfunction and Motor Severity in Children With CP
This study aims to examine the function of the temporomandibular joint (TMJ)-the jaw joint-in children with cerebral palsy (CP).
- Trial name
- NCT07043517
- Testing
- RDC/TMD
- Where
- Turkey (Türkiye)
- Volunteers
- 517 people
- Sponsor
- Istanbul Arel University
Cerebral Palsy, Anxiety
Does Anxiety Affect Balance, Spasticity and Function in Children With Cerebral Palsy
children and adolescents with CP are at increased risk of developing mental health difficulties, particularly anxiety disorders, compared with their typically developing peers.
- Conditions
- Cerebral Palsy, Anxiety, Spasticity
- Trial name
- NCT07346430
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic
Influence of the Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Cerebral Palsy.
The aim of the study is to evaluate a short term influence of the Spinal Manipulation (SM) on the wrist muscles spasticity and manual dexterity in children with spastic Cerebral Palsy.
- Trial name
- SpiManCP (NCT03005938)
- Testing
- Spinal manipulation, Imitation of the spinal manipulation
- Where
- Ukraine
- Volunteers
- 85 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine