Clinical trials: Muscle Adaptation
Aerobic Capacity, Blood Flow Restriction (BFR) Training Effects
Low-Intensity BFR Cycling: Impact on VO₂Max and Muscle Adaptations
This study aims to investigate the effects of low-intensity cycling exercise combined with blood flow restriction (BFR) on maximal oxygen consumption (VO₂max), muscle strength, and muscle thickness in sedentary adult males.
- Conditions
- Aerobic Capacity, Blood Flow Restriction (BFR) Training Effects, Blood Flow Restriction Exercise, Muscle Strengh
- Trial name
- NCT07114835
- Testing
- Cycling with Blood Flow Restriction (15 min at 40% VO₂max with 60-80% LOP), Cycling Exercise (40 min at 40% VO₂max), Short-Duration Cycling Control (15 min at 40% VO₂max)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Electrical Stimulation
Influence of Electrode Positioning and Current Type on Fatigue, Force and Discomfort
Introduction: Neuromuscular electrical stimulation (NMES) has the purpose of generating muscle contractions to minimize muscular atrophy and to improve neuromuscular performance.
- Trial name
- NCT04200677
- Testing
- Monophasic Current (100 Hz) with 1ms pulse width applied to the Tibial Nerve, Biphasic current (100 Hz) with pulse width 0.5ms applied to the Tibial Nerve, Biphasic current (100 Hz) with 1ms pulse width applied to the Tibial Nerve
- Where
- 2 sites in Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Spinal Cord Injury(SCI)
Effects of Continuous Passive Motion on the Spinal Circuitries and Its Adaptation in Patients With Spasticity Resulting From Upper Motor Neuron Lesions
In animal and human studies, histochemical and physiological evidences showed that the muscle transferred from slow, fatigue-resistant muscle to fast, fatigable muscle after spinal cord injury.
- Trial name
- NCT02122276
- Testing
- Ankle continuous passive motion machine.
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- Chang Gung University
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Cardiovascular Diseases, Coronary Artery Disease
The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease
Benefits from cardiac rehabilitation (CR) programs are evidence based and widely recognized. Less than 50% of people who participate in hospital-based CR programs maintain an exercise regimen for as long as six months after…
- Trial name
- NCT03335319
- Testing
- Periodized Exercise Training Regime, Non Periodized Exercise Training Regime
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- University of Lisbon
Ankle Rehabilitation, Ankle Instability
Ankle Evertor and Invertor Strength Training
The aim of this study was to investigate the effects of a 12-week ankle evertor and invertor strength training program performed on a specially designed device, which allows isolated strengthening of evertor and invertor muscles.
- Conditions
- Ankle Rehabilitation, Ankle Instability, Ankle Sprain, Ankle Injuries and Disorders
- Trial name
- NCT07820449
- Testing
- Ankle Evertor and Invertor Strength Training
- Where
- Slovenia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Exercise
Protein Supplementation and Endurance Exercise Adaptations
Participants will perform three endurance training sessions weekly for 12 weeks. All participants will be randomly assigned to the protein supplementation group or the placebo (iso-caloric carbohydrate) group.
- Trial name
- NCT03462381
- Testing
- Protein
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Breast Cancer, Breast Cancer Female
THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation
The study's purpose is to evaluate whether creatine supplementation can help breast cancer survivors respond quicker to exercise by improving strength, endurance, and body composition.
- Conditions
- Breast Cancer, Breast Cancer Female, Muscle Weakness
- Trial name
- THRIVE (NCT06395506)
- Testing
- Creatine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Osteoarthritis, Back Pain
Investigation of the Cultural Adaptation, Validity, and Reliability of the Turkish Version of the CAP Questionnaire
The "CAP questionnaire," developed by modifying the CAP-Knee questionnaire to assess potential nociplastic pain features in painful musculoskeletal disorders, has been described.
- Conditions
- Osteoarthritis, Back Pain, Fibromyalgia
- Trial name
- NCT06825650
- Testing
- Questionnaire study
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Ferroptosis, Inflammation
Multifaceted Analysis of the Adaptation of Rowers in the Process of Sports Training
This study aims to analyze in detail selected indicators of appetite regulation, metabolism, and iron balance in competitive rowers undergoing intense exercise.
- Conditions
- Ferroptosis, Inflammation, Muscle Damage, Nervous System Diseases
- Trial name
- NCT06891820
- Testing
- Physical effort
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Burns, Pediatric Burns
Resistance, Plyometric, and Combined Exercise Training in Children With Severe Burns
Children who experience severe burns may continue to have reduced muscle strength, power, balance, and physical function after their wounds have healed.
- Conditions
- Burns, Pediatric Burns, Burn Injury
- Trial name
- NCT07843355
- Testing
- Traditional Resistance Training, Plyometric Training, Combined Resistance and Plyometric Training
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Qassim University
Duchenne Muscular Dystrophy, Ambulation Difficulty
Cultural Adaptation, Validity, and Reliability of the Turkish Version of North Star Ambulatory Assessment
The aim of this study is to translate the "North Star Ambulatory Assessment (NSAA)" scale into Turkish and make its cultural adaptation and to demonstrate the reliability and validity of the Turkish version in patients with…
- Conditions
- Duchenne Muscular Dystrophy, Ambulation Difficulty, Ambulation Disorder, Neurologic
- Trial name
- NCT05549999
- Testing
- North Star Ambulatory Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Hacettepe University
Aging, Exercise Training
Tendon Adaptations to Training - Effect of Ageing
Tendons are essential structures for transmitting muscle forces to skeletal structures. A stiffer tendon will transmit muscle force faster, and then allow faster movement.
- Conditions
- Aging, Exercise Training, Connective Tissue, Skeletal Muscle
- Trial name
- TAGE (NCT03079180)
- Testing
- Strength training at 80% 1RM, Strength training at 55% 1RM
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université de Technologie de Compiegne
Sarcopenia
Pilates and PNF Methods Induces Similar Strength Gains
To compare the influence of a training program with Pilates and PNF methods to elderly women on the strength gains and motor control during voluntary contractions
- Trial name
- NCT02274909
- Testing
- TRAINING PROGRAM
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do PiauÍ
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Intermittent Claudication, Peripheral Arterial Disease
Effect of Exercise on Patients With Claudication Undergoing Surgery
Title: How does exercise improve the calf muscle in patients with poor blood supply to their leg? Purpose of the project: Patients with peripheral arterial disease have a poor blood supply to their lower leg.
- Trial name
- NCT01980602
- Testing
- Supervised Exercise program
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Hull
Muscle-Invasive Bladder Carcinoma
Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients with Muscle Invasive Bladder Cancer
Evaluate the impact of 18F-FDG-PET-CT on the staging of patients with muscle invasive bladder cancer. Based on the results of 2 18F-FDG-PET-CT's patients are stratified in non-metastatic, oligometastatic and polymetastatic…
- Trial name
- EFFORT-MIBC (NCT04724928)
- Testing
- Metastasis directed therapy (MDT), Immunotherapy, Standard of care
- Where
- Belgium
- Volunteers
- 156 people
- Sponsor
- University Hospital, Ghent
Focus on Healthy Infants
Development of Muscle Function in Prepubertal Children As a Response to Growth and Resistance Training
Healthy skeletal muscle development is crucial for a life-long quality of life. Childhood and puberty may be key periods for developing muscle growth and neuromuscular capacities, which are essential for bone-muscle interaction…
- Trial name
- decade-fit (NCT06594900)
- Testing
- resistance training intervention
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ralf Roth
Basketball Performance
Lower Body Plyometric Training Effects on Upper Body in Basketball Players
The present study investigates effect of lower body plyometric training on upper body performance, muscle size, hormonal factors, and neuromuscular activity in male basketball players, with a focus on vertical strength transfer…
- Trial name
- LBPT-VST (NCT07339436)
- Testing
- Plyometric Training
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Birjand University of Medical Sciences
NON APPLICABLE
Training Load Adapted to Muscle Properties to Reduce Injury Occurrence in Sprint
During the Olympics, running fast is the most prevalent motor task, 100-m dash being the one of the most-expected event. Yet, the achievement of such running sprints requires both extreme athletic capabilities together with…
- Trial name
- FULGUR (NCT06619132)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris