Clinical trials: Muscle Activation, active
Chronic Shoulder Pain
Structure and Function of the Upper Trapezius and Its Role in Chronic Shoulder Pain: an Investigation of Kinematics, Morphology, Muscle Quality and Activation Distribution
Prior research has explored factors influencing muscle activation, including muscle thickness, fear avoidance beliefs (kinesiophobia), and somatosensory integration.
- Trial name
- NCT06472349
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Pregnancy
The Effect of Ultrasound Visual Feedback on Birth Outcomes in Nulliparous Women With Levator Ani Muscle Co-activation at Term Pregnancy
The study aims to evaluate the effect of ultrasound-based visual feedback training of the pelvic floor muscles in nulliparous women at term pregnancy who present co-activation of the levator ani muscle, on the duration of the…
- Trial name
- CoA_2025 (NCT07675642)
- Testing
- Ultrasound Visual Feedback Training
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Trapeziometacarpal Osteoarthritis
Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb…
- Trial name
- NCT07866703
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaga
HIV Infections
Cardiovascular Responses to Exercise in People Living With HIV/AIDS: Effects of Exercise Training
Patients living with HIV (PLWHIV) have compromised muscle metaboreflex, which can cause exercise intolerance. This randomized controlled clinical trial will verify the effects of regular exercise on autonomic and hemodynamic…
- Trial name
- NCT04512456
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Flat Feet, Lower-Limb Muscle Activation
Plantar Stimulation, Whole-Body Vibration, and Baduanjin for Muscle Activation
This study will examine how different short-term exercise and vibration conditions affect lower-limb muscle activity in young adults with flat feet and young adults with normal feet.
- Conditions
- Flat Feet, Lower-Limb Muscle Activation, Neuromuscular Response
- Trial name
- NCT07811674
- Testing
- Whole-body Vibration Training,Whole-Body Vibration With Regional Plantar Stimulation,Baduanjin
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Non-specific Neck Pain, Playing Related Musculoskeletal Disorders
Kinematics and Muscle Activation of Scapula in Upper String Players With Neck Pain
This study will analyze and compare scapular kinematics and muscle activation patterns between upper string musicians with and without neck pain during arm elevation and playing tasks (open strings, scales, musical pieces)…
- Trial name
- NCT07448857
- Testing
- motion capture system, surface electromyography
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
Hematopoietic and Lymphatic System Neoplasm, Recurrent Ependymoma
Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
This phase II pediatric MATCH treatment trial studies how well selpercatinib works in treating patients with solid tumors that may have spread from where they first started to nearby tissue, lymph nodes, or distant parts of the…
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Recurrent Ependymoma, Recurrent Ewing Sarcoma, Recurrent Hepatoblastoma
- Trial name
- NCT04320888
- Testing
- Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography
- Where
- 174 sites in United States, Australia and 1 more
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children
Surface Electromyographic Analysis of Normal Swallowing in Children: An Exploratory Study
This exploratory clinical trial aims to investigate the mechanism of sequential muscle contractions during normal swallowing processes, including spoon, straw, and cup feeding, in children aged 2 to under 10 years without…
- Conditions
- Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children, Swallowing Function
- Trial name
- NCT07455279
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
SCI - Spinal Cord Injury, PD - Parkinson's Disease
Differential Assessment of Hypertonia
Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements.
- Trial name
- NCT06596187
- Testing
- Continuous passive motion device (CPM) of ankle - fast, Continuous passive motion device (CPM) of ankle - slow
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Intensive Care Unit Acquired Weakness, Critical Illness
Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise
Up to 60% of patients admitted to the Intensive Care Unit (ICU) with a prolonged stay in the ICU develop complications such as intensive care unit acquired weakness (ICUAW) characterized by limb and respiratory muscle weakness.
- Trial name
- NCT05279547
- Testing
- Constant-load bed-cycling exercise, Interval bed-cycling exercise
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Chronic Kidney Disease, Renal Insufficiency, Chronic
Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease
This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Disease, Renal Insufficiency, Chronic, Muscle Weakness, Sarcopenia
- Trial name
- NCT07292311
- Testing
- Reliability Assessment, Online Therapeutic Exercise
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Cerebral Palsy (CP), Cerebral Palsy
Dorsal Root Electrical Stimulation in Children With Cerebral Palsy
The goal of this clinical trial is to evaluate whether dorsal root electrical stimulation could reduce spasticity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Cerebral Palsy, Spasticity, Spasticity Due to Cerebral Palsy
- Trial name
- NCT07715006
- Testing
- Constant Current Stimulator, Cadwell Guardian System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Martin Piazza
Sports Physical Therapy, Injury;Sports
Inspiratory Muscle Activation and Post-Exercise Recovery in Professional Football Players
Respiratory muscles play a fundamental role in sports performance. Fatigue of these muscles induces changes in maximal inspiratory pressure and autonomic nervous system activity, thereby compromising the athlete's recovery…
- Trial name
- NCT07373158
- Testing
- Inspiratory muscle activation via phrenic nerve modulation, Inspiratory muscle activation via threshold device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
ICU Acquired Weakness, Muscle Atrophy
Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
Intensive Care Unit Acquired Weakness (ICUAW) describes muscle weakness that occurs in around 40% of patients during an intensive care stay.
- Conditions
- ICU Acquired Weakness, Muscle Atrophy, Energy Malnutrition Protein, Quality of Life
- Trial name
- NCT05919940
- Testing
- Dietary Supplement: additional substitution of protein, Neuromuscular electrical stimulation, Early Mobilization
- Where
- 4 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Chronic Migraine
Mechanism-Based Cervical Rehabilitation for Chronic Migraine
To investigate the effectiveness of mechanism-based cervical sensorimotor rehabilitation on cervical muscle activation, cervical proprioception, and migraine burden.
- Trial name
- NCT07762690
- Testing
- cervical sensorimotor rehabilitation, conventional physiotherapy programme
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Adolescent Idiopathic Scoliosis (AIS)
Wireless EMG-Based Monitoring of Paraspinal Muscle Activation in Adolescent Idiopathic Scoliosis
This study aims to develop and evaluate a wireless, non-invasive, embedded electromyography (EMG) system for monitoring paraspinal muscle activation asymmetries in adolescents with idiopathic scoliosis.
- Trial name
- AIS-EMG (NCT07738588)
- Testing
- Wireless Embedded Surface EMG (sEMG) Measurement System
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ertugrul Deniz Kose
Spinal Cord Injured, Post-stroke
Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries.
Neurological disorders [such as Cerebral Vascular Accident (CVA) or Spinal Cord Injury (SCI)] are among the most costly health problems to society in industrialized countries.
- Trial name
- RenfExc (NCT06099340)
- Testing
- muscle-strengthening program
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital
Critical Illness Myopathy
NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness
The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illness myopathy (CIM).
- Trial name
- PT-NLRP3-CIM (NCT07017517)
- Testing
- Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
- Where
- 3 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile