Clinical trials: Motor and Developmental Delay
Smith-Magenis Syndrome (SMS)
Natural History Study of Smith-Magenis Syndrome
This study will examine how a rare disease called Smith-Magenis syndrome (SMS) affects people and how they change over time. SMS is caused by a small chromosome 17p11.2 deletion (missing piece).
- Trial name
- NCT00013559
- Where
- United States
- Volunteers
- 593 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Infants With or at Risk/Concern for Developmental Delay
Otteroo Case Series
Rationale. The Otteroo is a floatie which supports an infant or young child with their head above and their body in water. Researchers are proposing that the Otteroo may be a good "tool" to facilitate exploring the ability to…
- Trial name
- NCT03502265
- Testing
- Otteroo
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Developmental Delay
Early Intervention Therapy for Children With Delayed Development: Enabling Access in India's Rural Communities
This study is a cohort longitudinal design, also known as within subject repeated measures' design to measure the impact of an early identification and intervention program being implemented by Amar Seva Sangam (ASSA), an Indian…
- Trial name
- NCT03202966
- Testing
- Rehabilitation therapy
- Where
- 2 sites in India
- Volunteers
- 1,050 people
- Sponsor
- Amar Seva Sangam
Deafness, Hearing Loss
Outcomes In Children With Developmental Delay And Deafness
Children with special needs require complex, individualized therapy to maximize their long-term quality of life. One subset of children with special needs includes those with both developmental delays and deafness.
- Trial name
- NCT01256229
- Testing
- cochlear implantation, hearing aids
- Where
- 2 sites in United States
- Volunteers
- 303 people
- Sponsor
- Stanford University
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Developmental Delay
Effects of Rainbow Parachute Games on UE Strength and Social-Emotional Skills in Children With Developmental Delay
Conducted as a randomized trial, this study examines the impact of rainbow parachute games on upper extremity strength and social-emotional skills in children (ages 5-8) with developmental delays.
- Trial name
- NCT07756931
- Testing
- Rainbow parachute Games, Rhyming Activities
- Where
- Pakistan
- Volunteers
- 12 people
- Sponsor
- Riphah International University
Cerebral Palsy Infantile, Pre-Term
Motor-voice Assessment in Infants (MAMI)
The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disability in infants..
- Conditions
- Cerebral Palsy Infantile, Pre-Term, Motor Delay, Neurodevelopmental Disorders
- Trial name
- MAMI (NCT06807203)
- Testing
- Behavioral observation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Ohio State University
Cerebral Palsy, Chewing Problem
Chewing Performance Level and Gross Motor Function in Children With Cerebral Palsy
The purpose of this study is to determine the association between gross motor function and chewing performance level in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy, Chewing Problem, Gross Motor Development Delay
- Trial name
- NCT02984735
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Hacettepe University
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Cerebral Palsy, Developmental Delay
Clinical Effectiveness of Increased Standing Time in Non-ambulant Children With Cerebral Palsy:a Pilot Study
Children with cerebral palsy commonly use standing frames to position them to help prevent contracture and deformity and to help their function. There is a lack of evidence to support the correct dosage of standing frame use.
- Trial name
- NCT02141802
- Testing
- Doubling standing time, control
- Where
- 4 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Rachel Rapson
Child Development, Parenting
Caregiver Interventions for Developmental Delays in Young Kenyan Children
In this study, the investigators will only administer the intervention to children known to have neurodevelopmental delays. By focusing on adapting the intervention to be only a clinic-based treatment, a small number of community…
- Conditions
- Child Development, Parenting, Cognitive Developmental Delay
- Trial name
- NCT03612505
- Testing
- Mother groups using principles of UNICEF/World Health Organization's Care for Child Development
- Where
- Kenya
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Indiana University
MNRI, Development Delay
Effects of MNRI Therapy on Fine Motor Skills in Children With Developmental Delays.
Developmental delay refers to a child's failure to achieve age-appropriate developmental milestones and may affect multiple developmental domains.
- Trial name
- NCT07764926
- Testing
- MNRI, Conventional Physiotherapy without MNRI
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Developmental Delay
Occupational Therapy in the Context of Head Start
The purpose of this study is to identify the role of occupational therapy within Head Start programs. Representatives within Head Start will be asked to participate in a nationwide internet based survey identifying the amount and…
- Trial name
- NCT01975506
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Texas Woman's University
Intellectual Disability, Developmental Delay
Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
The study uses a randomized controlled study design of pediatric neurologists and developmental pediatricians and front-line (primary care) pediatricians to determine if use of FirstStepDx PLUS and Next StepDx PLUS are associated…
- Trial name
- NCT02414438
- Testing
- FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Epilepsy, Mental Retardation
Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population
This study is being done to see if children with learning problems can learn how to swallow pills without chewing them. The reason this is important is that if a person has seizures, medications must be taken every day.
- Conditions
- Epilepsy, Mental Retardation, Developmental Disabilities
- Trial name
- NCT00207935
- Testing
- Swallow instruction
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's National Research Institute
Neurodevelopmental Disorders, Intellectual Disability
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND (developmental delay, epilepsy and neonatal diabetes) due to the V59M…
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD
- Trial name
- iDEND (NCT05751525)
- Testing
- Sulfonylurea
- Where
- 4 sites in United States, Italy and 2 more
- Volunteers
- 21 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Neuro Developmental Delay, Sensory Disorders
Aquatic Therapy Versus Sensory Room Intervention for Sensory-Motor Function in Children With Sensory Processing Disorder
This randomized clinical trial compares the effects of aquatic therapy and conventional sensory room intervention on adaptive neural responses and sensory-motor praxis in children with Monochannel Sensory Processing Disorder.
- Trial name
- AQUA vs SRI Tr (NCT07646951)
- Testing
- Aquatic Therapy
- Volunteers
- 60 people
- Sponsor
- MTI University
Thyroid Gland; Node, Pregnancy
Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study
THE ULTIMATE GOAL of this project is to answer the question "In MILD IODINE DEFICIENCY (ID), should a tablet with vitamins and minerals, including 150 μg iodine/day be administered to pregnant women with a normal diet, to attain…
- Conditions
- Thyroid Gland; Node, Pregnancy, Cognitive Developmental Delay
- Trial name
- SWIDDICH (NCT02378246)
- Testing
- Iodine
- Where
- 4 sites in Sweden
- Volunteers
- 1,337 people
- Sponsor
- Göteborg University
Autism Spectrum Disorder, Developmental Delay
Validation of a Salivary miRNA Diagnostic Test for ASD
This study involves sample collection to identify biomarkers relating to Autism Spectrum Disorder(ASD) in the saliva of children who are between the ages of 18 months to 6 years and 11 months.
- Trial name
- NCT05418023
- Testing
- Salivary Collection, Adaptive Assessment, Medical and Demographic questionnaire
- Where
- 16 sites in United States
- Volunteers
- 6,604 people
- Sponsor
- Quadrant Biosciences Inc.
Nutrition Disorder, Child, Gross Motor Development Delay
Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Background: Most patients with cerebral palsy (CP) are dependent on parents due to the spasticity and limitations in their gross motor function.
- Conditions
- Nutrition Disorder, Child, Gross Motor Development Delay, Neuro: Cerebral Palsy, Diet Modification
- Trial name
- ENSSIGMCP (NCT03933709)
- Testing
- Nutritional Support System (NSS), deworming, recommended diet
- Volunteers
- 30 people
- Sponsor
- Anahuac University