Clinical trials: Morphine Consumption
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Taken together, studies of the value of pre-emptive analgesia are inconclusive. This randomized, double-blind, dose-ranging, placebo-controlled study was therefore designed to test that a reduction in post-operative morphine…
- Conditions
- a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption, Total Pain Relief Over 8 Hr(TOPAR8), Post Transabdominal Hysterectomy
- Trial name
- NCT00149253
- Testing
- a single-dose of Etoricoxib before induction of anesthesia
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Postpartum Pain, Postpartum Depression
Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery
Patients presenting for normal spontaneous vaginal delivery who have a neuraxial anesthestic will be randomized to receive preservative free morphine or saline placebo after delivery.
- Conditions
- Postpartum Pain, Postpartum Depression, Opioid Consumption
- Trial name
- NCT04017442
- Testing
- Preservative Free Morphine, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anesthesia, Analgesia
Preoperative Dexamethasone to Improve Quality of Recovery After Laparoscopic Bariatric Surgery
In the obese patient, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay.
- Conditions
- Anesthesia, Analgesia, Acute Pain
- Trial name
- NCT05752734
- Testing
- Group D, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
The goal of this clinical trial is to learn whether suzetrigine (Journavx®), when added to standard multimodal pain management, can reduce opioid use while providing adequate pain control in adults undergoing surgery for an acute…
- Trial name
- STRIDE-HIP (NCT07905404)
- Testing
- Suzetrigine (Journavx)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Beth Israel Deaconess Medical Center
Morphine Consumption, Pain
Serratus Anterior Plan Block and Postoperative Pain in Patients Who Underwent Minimally Invasive Cardiac Surgery
Acute postoperative pain is defined as sudden onset pain that develops after stimulation due to surgical intervention. It is most severe in the first 24 hours after surgery and gradually decreases in severity and creates…
- Trial name
- NCT06002867
- Testing
- SAPB (Serratus Anterior Plan) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cardiac Surgery, Post-operative Pain
Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy
Currently, the management of pain after cardiac surgery is based on the concept of multimodal analgesia: Combined use of non-opioid analgesics associated with morphine intravenous analgesia by a system controlled by the patient…
- Trial name
- LoDoNSAID (NCT02180087)
- Testing
- Ketoprofen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Ureteral Calculi, Hyperalgic, Not Complicated
Nefopam and Morphine Consumption in the Treatment of Ureteral Calculi
The administration of néfopam after initial treatment by kétoproféne, could obtain, in patients remaining pain and classically need morphine, analgesia at least the same as morphine alone.
- Trial name
- NCT00639574
- Testing
- Néfopam
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Pain, Total Hip Replacement
Morphine COnsumption in Joint Replacement Patients, With and Without GaBapentin Treatment, a RandomIzed ControlLEd Study
Total hip arthroplasty is amongst the most painful procedures postoperatively, and pain management can be a challenge. Different measures have been introduced to manage severe postoperative pain in these patients.
- Trial name
- MOBILE (NCT00889148)
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- McMaster University
Postoperative Pain Management
Escalating Ketamine Doses and Pre-emption
Ketamine affects postoperative pain when administered intravenously immediately before, during or at the end of surgical procedures.
- Trial name
- NCT01070108
- Testing
- Ketamine
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Sleep Apnea
Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
The purpose of this study is to determine if Dexmedetomidine given at the end of surgery will reduce postoperative morphine consumption and improve postoperative quality of recovery as compared to morphine in patients undergoing…
- Conditions
- Obesity, Sleep Apnea, Diabetes, Hypertension
- Trial name
- NCT02213159
- Testing
- Dexmedetomidine, Morphine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- American University of Beirut Medical Center
Postoperative Analgesia
Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal Surgery
.The aim of this study is to identify the analgesic effect of intraoperative ketamine intravenous infusion on patients undergoing intestinal surgery and its effect on salivary cortisol and alpha amylase levels as indicator of its…
- Trial name
- NCT03344393
- Testing
- Ketamine Hydrochloride, Normal saline
- Volunteers
- 60 people
- Sponsor
- Assiut University
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Postoperative Pain
Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty
This study evaluates continous infusion of low-dose ketamine during intraoperative and postoperative periods at three different doses to provide postoperative analgesia in total knee arthroplasty cases.
- Trial name
- NCT04085588
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Mustafa Kemal University
Tooth Extractions
Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery
Wisdom teeth removal under general anaesthesia is usually suitable for ambulatory surgery. The choice of opioid in dental day surgery is based on the need for a rapid and full recovery, as well as less morphine administration.
- Trial name
- SUF-REM-DDS (NCT01139671)
- Testing
- Remifentanil
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Abdominal Wall Hernia
Laparoscopic "DA VINCI" Robot Assisted Abdominal Wall Hernia Repair
The aim of this study is to prove the superiority of the robotic assistance in laparoscopic repair of abdominal wall hernias . In this monocentric randomized controlled trial, the use of the DA VINCI robot might reduce the…
- Trial name
- ARTE (NCT00908193)
- Testing
- Laparoscopic DA VINCI Robot Assisted coelioscopy, conventional coelioscopy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Fractures, Methadone
Perioperative Methadone Compared to Placebo in Elderly Hip Fracture Patients
Hip fractures are associated with severe pain and are sustained by the elderly population. Demand for adequate pain relief combined with a low tolerance for analgesic drugs makes the treatment of elderly hip fracture patients…
- Trial name
- NCT06086171
- Testing
- Methadone Hydrochloride
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- University of Southern Denmark
Postoperative Pain, Knee Arthroplasty
The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty
The objective of this study is to assess the efficacy of Adductor-Canal-Blockade on pain and morphine consumption after total knee arthroplasty.
- Trial name
- NCT01261897
- Testing
- Adductor-Canal-Blockade with Ropivacaine, Adductor-Canal-blockade with saline
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post Operative Analgesia
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps
Continuous bupivacaine administration through an elastomeric pump (Pain Buster) has been found effective for post operative analgesia in a large range of surgery.
- Trial name
- NCT00724685
- Testing
- Naropeine (Ropivacaine)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Postoperative Pain Management
Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery
Primary aim of this prospective, randomized, double-blind, placebo-controlled clinical trial is to compare the analgesic effects of IV ibuprofen and paracetamol on postoperative pain, and secondary aim is the effects on morphine…
- Trial name
- ibuprofen (NCT03437707)
- Testing
- Morphine Sulfate, Intravenous paracetamol, Intravenous ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Inonu University