Clinical trials: Moderate Acute Malnutrition (MAM)
Moderate Acute Malnutrition (MAM)
Supplementary Food on Prevention of Moderate Malnutrition in Children
The study will evaluate the impact of a supplementary food (cookies) in preventing the risk of developing moderate acute malnutrition (MAM) in preschool mildly malnourished children.
- Trial name
- NCT02572258
- Testing
- Nutritional cookie
- Where
- Mexico
- Volunteers
- 1,048 people
- Sponsor
- PepsiCo Global R&D
Severe Acute Malnutrition, Moderate Acute Malnutrition
Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition
This single-center, randomized, open-label trial will compare the safety of MTT delivered by rectal catheter enema in participants 12-60 months of age with malnutrition (moderate acute malnutrition [MAM] or severe acute…
- Trial name
- THRIVE (NCT03087097)
- Testing
- Fecal Microbiota Transplantation
- Where
- South Africa
- Volunteers
- 5 people
- Sponsor
- Microbiome Health Research Institute
Malnutrition
Whey Permeate Study
This is a prospective, randomized, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM.
- Trial name
- NCT01790048
- Testing
- Whey permeate RUSF, Soy Protein RUSF
- Where
- Malawi
- Volunteers
- 2,259 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition
Microbiota Directed Food for Children With Moderate Acute Malnutrition
Moderate acute malnutrition (MAM) refers to a condition characterized by a significant deficit in weight-for-length measurements in children aged 6 to 59 months.
- Trial name
- NCT06305442
- Testing
- Microbiota-Directed Food, Ready-to-Use Supplementary Food
- Where
- Bangladesh
- Volunteers
- 230 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Severe Acute Malnutrition, Moderate Acute Malnutrition (MAM)
Regular Growth Monitoring (RGM) of Young Children in Guinea-Bissau
Wasting (severe thinness) is a common and serious problem among young children in rural Guinea-Bissau. Community Health Agents (CHAs) can help prevent malnutrition by regularly measuring children's growth and advising families on…
- Trial name
- NCT07584395
- Testing
- Regular Growth Monitoring (RGM) by Community Health Agents
- Where
- Guinea-Bissau
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Microbiota, Complementary Food
Community-based Clinical Trial With Microbiota Directed Complementary Foods (MDCFs) Made of Locally Available Food Ingredients for the Management of Children With Post-severe Acute Malnutrition Moderate Acute Malnutrition (Post-SAM MAM)
Background (brief): 1. Burden: A total of 52 million children under 5 are suffering from acute malnutrition globally, of whom 33 million suffer from moderate acute malnutrition (MAM).
- Conditions
- Microbiota, Complementary Food, Nutrition
- Trial name
- NCT04015986
- Testing
- Microbiota Directed Complementary Food-2, Ready to Use Supplementary Food
- Where
- Bangladesh
- Volunteers
- 124 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition
Treatment of High-Risk Moderate Acute Malnutrition Using Expanded Admission Criteria
This project explores whether children have better growth and cognitive development when the clinic identifies "higher risk" MAM children and support them either with the same treatment as SAM children or with the recommended…
- Trial name
- Hi-MAM (NCT03647150)
- Testing
- amoxicillin, Ready-to-use therapeutic food (RUTF), Mother Care group
- Where
- Sierra Leone
- Volunteers
- 1,322 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition
Choline to Prevent SAM in Children With MAM
The goal of this clinical trial is to test choline supplementation in children with moderate acute malnutrition in Malawi. The main question it aims to answer is: Will provision of RUSF with added choline (500mg/day) throughout…
- Trial name
- CHOP-MAM (NCT06214897)
- Testing
- C-RUSF (Ready-to-use Supplemental Food with added Choline), S-RUSF (Ready-to-use Supplemental Food without added Choline)
- Where
- 10 sites in Malawi
- Volunteers
- 1,515 people
- Sponsor
- Washington University School of Medicine
Malnutrition
Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra Leone
The long-term objective of this proposal is to develop and demonstrate an effective, integrated and streamlined protocol to treat moderate acute malnutrition (MAM) and non-complicated severe acute malnutrition (SAM) in children…
- Trial name
- NCT01785680
- Testing
- Integrated Protocol, Current protocol
- Where
- Sierra Leone
- Volunteers
- 1,957 people
- Sponsor
- Washington University School of Medicine
Malnutrition
Comparison of a Two Ready-to-use Supplementary Foods of Differing Protein Quality for the Treatment of MAM.
This is a prospective, randomised, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM. The setting will be 21 rural sites in southern Malawi.
- Trial name
- NCT03549156
- Testing
- C-RUSF, HIPRO RUSF
- Where
- Malawi
- Volunteers
- 1,858 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition
Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-MAM (NCT06056089)
- Testing
- ready-to-use supplementary food (RUSF), ready-to-use therapeutic food (RUTF)
- Where
- 3 sites in Ethiopia
- Volunteers
- 2,400 people
- Sponsor
- Action Against Hunger USA
Moderate Acute Malnutrition (MAM), Undernutrition
Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh
The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance/Hearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to…
- Conditions
- Moderate Acute Malnutrition (MAM), Undernutrition, Wasting
- Trial name
- PD/Hearth MAM (NCT07591064)
- Testing
- PD/Hearth is a behavioral change program that teaches caregivers how to cook and feed their children. A nutrient-dense meal using local ingredients will be fed to children during Hearth sessions., Standard of Care (Investigator Selected)
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- World Vision US
Moderate Acute Malnutrition (MAM)
Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Management of Moderate Acute Malnutrition in Niger (Related to NCT06382857 Protocol)
The study consisted of two phases. Phase 1 was a recipe development phase, which aimed to identify recipes that meet ≥80% of the recommended nutrient profile for Specially Formulated Foods (SFF) used in the standard management of…
- Trial name
- LAF (NCT07506213)
- Testing
- Locally Available Food
- Where
- Niger
- Volunteers
- 30 people
- Sponsor
- Epicentre
Moderate Acute Malnutrition (MAM)
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition (MAM) in Children in Sierra Leone: a Cluster-randomised, Controlled Clinical Effectiveness Trial
The objective of this study is to test and compare the effectiveness and cost-effectiveness of four supplementary foods for the treatment of moderate acute malnutrition (MAM) in normal programmatic settings in Sierra Leone.
- Trial name
- NCT02077907
- Testing
- Super Cereal Plus (SC+), Super Cereal (SC), fortified oil, sugar, Plumpy Sup
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Tufts University
Moderate Acute Malnutrition (MAM)
Management of Children With Moderate Acute Malnutrition in Mali
The objectives of the study are to assess the impact of different dietary strategies for the management of children with MAM on: the children's continued participation in the nutritional rehabilitation program and their physical…
- Trial name
- Mali-MMAM (NCT01015950)
- Testing
- Plumpy'Sup, Local food supplement, Misola
- Where
- Mali
- Volunteers
- 1,260 people
- Sponsor
- Helen Keller International
Moderate Acute Malnutrition
Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition
The research seeks to determine the relative effectiveness and cost effectiveness of alternative supplementary foods in the treatment of moderate acute malnutrition (MAM) in normal program settings.
- Trial name
- NCT03146897
- Testing
- Supplementary Food
- Where
- Sierra Leone
- Volunteers
- 2,691 people
- Sponsor
- Tufts University