Clinical trials: Missing Teeth
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Missing Teeth
Peri-implant Health of Dental Implants in the Posterior Region; an Evaluation After 10 Years
Background Adaptation of a dental implant and its restoration to the existing anatomy in the region of a missing tooth is presumed to be a reliable procedure.
- Trial name
- Performance (NCT05650099)
- Testing
- One or two dental implants (Biomet3I dental implant system) were placed 10 years ago
- Where
- Netherlands
- Volunteers
- 126 people
- Sponsor
- University Medical Center Groningen
Loss of Teeth Due to Extraction
Comparison of Two Different Alveolar Ridge Preservation Techniques
The purpose of this study is to compare two barrier membrane products, Cytoplast (dPTFE) and BioXclude (human amnion chorion allograft), for their relative efficacies in dental socket preservation procedures, both when the socket…
- Trial name
- NCT02482987
- Testing
- dense polytetrafluoroethylene (dPTFE) membrane Cytoplast, human amniotic-tissue derived membrane BioXclude, Ridge Preservation with overlay graft
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Eisenhower Army Medical Center
Hypodontia, Decision Making ,Shared
Improving Decision-Making for Missing Upper Front Teeth
Background: The developmental absence of 1-2 upper front teeth is a common condition, affecting 1 in 50 people worldwide, and affects smile aesthetics and quality-of-life.
- Conditions
- Hypodontia, Decision Making ,Shared, Decision Aid
- Trial name
- NCT07655193
- Testing
- Interview / Focus group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Tooth Lost
Extraction Socket Management Using Connective Tissue Graft Versus Mucograft®
This study aims at assessing the hard and soft tissues remodelling of the alveolar crest after extraction socket managements in the aesthetic areas: 3D radiographic evaluation (CT scan) was performed post extraction and 3 months…
- Trial name
- NCT02753153
- Testing
- Control surgical protocol, Test surgical protocol, Socket preservation
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Liege
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement
Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCT
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment
- Trial name
- JUMP-ESTHETIC (NCT07700706)
- Testing
- No Grafting, Silicate-Added β-TCP Putty, Extended Sticky Bone
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Denture, Partial, Fixed, Resin-Bonded, Tooth Loss / Rehabilitation
Clinical Outcomes of CAD/CAM Single-Retainer Monolithic Zirconia Ceramic Resin-Bonded Fixed Dentures Bonded With Two Different Resin Cements
Congenitally missing tooth is one of the most common anomalies in human dentition. The treatment options of lateral incisor agenesis are closing the space with orthodontic treatment, implant treatment, conventional fixed dental…
- Conditions
- Denture, Partial, Fixed, Resin-Bonded, Tooth Loss / Rehabilitation, Resin Cements
- Trial name
- NCT04491097
- Testing
- Panavia V5 resin cement, Panavia F2.0 resin cement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Bone Cysts, Bone Atrophy
Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone…
- Conditions
- Bone Cysts, Bone Atrophy, Bone Deformity, Bone Fracture
- Trial name
- NCT03076138
- Testing
- Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Histograft Co., Ltd.
Missing Teeth
Expectation and Satisfaction of Implant Rehab After Jaw Surgery
Objective: The aim of this prospective study was to investigate the patient-reported outcome measures (PROMs) of implant-supported prostheses (ISP) among patients who had excised pathological jaw lesions.
- Trial name
- NCT04873635
- Testing
- Implant support prostheses
- Volunteers
- 31 people
- Sponsor
- The University of Hong Kong
Tooth Loss, Ceramic Implant
PMCF Study of CeraRoot Ceramic Implants One-piece: 3 Years Follow up
The main objective is to evaluate the success / failure rate of CeraRoot ceramic implants (one piece) during three year follow up.
- Trial name
- NCT04598776
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- CeraRoot SL
Dental Implants, Tooth Loss
Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.
Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.
- Trial name
- NCT04497571
- Testing
- Piezoelectric osteotomy., Conventional drilling
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Orthodontics, Bracket Bonding
Comparison of Bond Failure with Resin-modified Glass Ionomer Cement and Visible Light-cure Composite Bonding Material in Adult Orthodontic Patients - a Split-Mouth, Randomized Controlled Trial
In this split mouth study design, 34 orthodontic patients coming for fixed appliance treatment will be bonded with standard light-cure composite bonding material and intervention of Resin Modified Glass Ionomer Cement (RMGIC).
- Conditions
- Orthodontics, Bracket Bonding, Malocclusion; Displaced or Missing Teeth
- Trial name
- RMGIC (NCT06602154)
- Testing
- Resin modified glass ionomer
- Where
- 2 sites in Pakistan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Missing Teeth
Clinical Trial of Zirconia and Metal Adhesive Bridges
Adhesive bridges are becoming popular in patients with congenitally missing teeth and these are type of bridges that can be done with only minimal or with no preparation to replace the missing tooth/teeth.
- Trial name
- NCT01347177
- Testing
- Zirconia-based adhesive bridge, Metal-based adhesive bridge
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tooth Loss, Dental Implant, Single-tooth
RCT of BLT Implants Used for Immediate vs Early Placement, Restored With Ceramic Crowns on Titanium Bonding Bases.
The purpose of this study is to assess the outcome of a new bone level tapered implant when inserted either following an immediate placement protocol or an early placement approach and restored with single crowns out of two…
- Trial name
- BLT (NCT05079542)
- Testing
- Timepoint of Implant placement of Bonelevel tapered implants, Material for tooth restoration - Lithiumdisilicate glass ceramic or zirconia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Tooth Loss
Allogenic Bone Block for Oro-Antral Communication Closure for Subsequent Implant Placement
13 patients will be included in this study with a badly destructed upper molar indicated for extraction. Cone beam computerized tomography images revealed the presence of a large bone defect associated with oro-antral…
- Trial name
- CAD-CAM (NCT07604142)
- Testing
- Extraction will be performed atraumatically using a piezotome surgical motor with an extraction kit
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Tanta University
Teeth Missing
Evaluation of the Related Factors Influencing the Stability of Dental Implants
With the development of oral medicine,dental implants has become a very popular solution to remediate the loss of teeth and dental rehabilitation.
- Trial name
- NCT02733861
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Alveolar Bone Loss, Maxillary Sinus Disease
Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation
This randomized controlled study aims to evaluate the clinical, radiographic, and histologic efficacy of using bioactive glass bone graft (UNIGRAFT by Biomed Inc., USA) compared to a conventional xenograft in maxillary sinus…
- Conditions
- Alveolar Bone Loss, Maxillary Sinus Disease, Tooth Loss
- Trial name
- BIOXENO (NCT07125846)
- Testing
- Bioactive Glass Bone Graft (UNIGRAFT), Xenograft Bone Graft (Bio-Oss)
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Missing Tooth/Teeth
Clinical Assessment of the Efficacy of Amy Check Versus Osstell Regarding the Accuracy of Implant Stability Measurements When Inserted With Graftless Closed Sinus Lifting: A Randomized Controlled Clinical Trial
The aim of the study is to compare clinically the efficacy of Amy check device versus Osstell device in evaluating the implant stability of implants placed simultaneously with transcrestal sinus lifting.
- Trial name
- NCT07827950
- Testing
- Implant with sinus lifting
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University