Tooth Loss in the Esthetic Zone Requiring Immediate Implant PlacementJUMP-ESTHETICNCT07700706
Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCT
A study testing No Grafting, Silicate-Added β-TCP Putty and Extended Sticky Bone in people with Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement and Guided Immediate Implant Placement, run by Mansoura University at 1 site in Egypt.
Trial summary
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone. Clinical and digital outcomes will be evaluated after immediate provisionalization and final restoration. Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting
- What is being tested?
- No Grafting, Silicate-Added β-TCP Putty and Extended Sticky Bone
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 72 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Dec 2025to 30 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with non-restorable teeth in maxillary esthetic zone requiring dental extraction.
- Age range: from18 to 50 years.
- Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration.
- Jumping gap more than 2mm.
- Patients with good oral hygiene.
- Patients willing to participate in the study's follow-up intervals.
Who cannot join
- Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement.
- Alcohol or drug abuse.
- Smokers.
- Patients with systemic diseases that absolutely contraindicate implant placement (bleeding disorders, immunosuppression,…etc.)
- Pregnancy.
- Patients with para-functional habits (bruxism and clenching).
- Lack of motivation or inability to maintain good oral hygiene.
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Dentistry Mansoura University
Al Mansurah, Dakahlia Governorate
About this study
Official title: Clinical and Digital Outcomes of Silicate-Added β-TCP Putty and Extended Sticky Bone for Peri-Implant Jumping Gap Management Following Fully Guided Immediate Implant Placement in the Maxillary Esthetic Zone: A Randomized Clinical Trial
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone. Clinical and digital outcomes will be evaluated after immediate provisionalization and final restoration.
Read the detailed description
Seventy two patients will be randomly assigned to receive no graft, silicate-added β-TCP putty, or extended sticky bone for jumping gap management around immediately placed implants. A CAD/CAM provisional crown will be delivered immediately, and the final prosthesis will be placed after 3 months.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment, Provisional Crown
- Being tested
- No Grafting, Silicate-Added β-TCP Putty, Extended Sticky Bone
- Keywords
- Immediate implant placement, Fully guided surgery, Jumping gap management, Peri-implant defect, Silicate-added β-TCP putty, Extended sticky bone, Bone grafting, Maxillary esthetic zone, Immediate provisionalization, Clinical outcomes, Digital outcomes, Randomized clinical trial
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No GraftingProcedure or surgery
The peri-implant jumping gap was managed without grafting.
Silicate-Added β-TCP PuttyProcedure or surgery
The peri-implant jumping gap was managed using silicate-added β-TCP putty.
Extended Sticky BoneProcedure or surgery
The peri-implant jumping gap was managed using extended sticky bone.
| Study group | Role | What they receive |
|---|---|---|
| Control group | Experimental | Fully guided immediate implant placement with an ungrafted peri-implant jumping gap and immediate CAD/CAM provisionalization. Receives: Procedure: No Grafting |
| Study Group 1 (Si-β-TCP Putty Group) | Experimental | Fully guided immediate implant placement with a peri-implant jumping gap filled using silicate-added β-TCP putty and immediate CAD/CAM provisionalization. Receives: Procedure: Silicate-Added β-TCP Putty |
| Study Group 2 (Extended Sticky Bone Group) | Experimental | Fully guided immediate implant placement with a peri-implant jumping gap filled using extended sticky bone and immediate CAD/CAM provisionalization. Receives: Procedure: Extended Sticky Bone |
What is being measured
The primary outcome is the main question the study is designed to answer.
Implant Stability
Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values).
Measured: Immediate post-operative, 3 months, and 6 months.
Hard Tissue (Peri-implant bone)
Marginal bone loss will be assessed using CBCT measured in mm.
Measured: - Immediately after implant placement - 6 months after implant placement.
Secondary outcomes (1)
Soft Tissue
Soft tissue contour and peri-implant tissue condition will be assessed using digital intraoral scanning (STL files) using superimposition and modified sulcus bleeding index (mSBI).
Measured: Baseline, 1 month, 3 months, and 6 months.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jul 2026
- Study start1 Dec 2025
- Primary completion30 Jun 2026
- Study completion30 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth Loss in the Esthetic Zone Requiring Immediate Implant PlacementStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 72 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07700706
- Sponsor's protocol ID
- R.26.06.128
- Acronym
- JUMP-ESTHETIC
- Status last verified
- Sep 2026
- First submitted
- 8 Jul 2026
- Last updated
- 22 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Digital Outcomes of Silicate-Added β-TCP Putty and Extended Sticky Bone for Peri-Implant Jumping Gap Management Following Fully Guided Immediate Implant Placement in the Maxillary Esthetic Zone: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07700706
- Acronym / sponsor ID
- JUMP-ESTHETIC / R.26.06.128
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment, Provisional Crown
- Keywords
- Immediate implant placement, Fully guided surgery, Jumping gap management, Peri-implant defect, Silicate-added β-TCP putty, Extended sticky bone, Bone grafting, Maxillary esthetic zone
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 72 participants (actual)
- Lead sponsor
- Mansoura UniversityUniversity, hospital or other
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 30 Jun 2026 (actual)
- Study completion
- 30 Jul 2026 (actual)
- First posted
- 14 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone. Clinical and digital outcomes will be evaluated after immediate provisionalization and final restoration.
Detailed description
Seventy two patients will be randomly assigned to receive no graft, silicate-added β-TCP putty, or extended sticky bone for jumping gap management around immediately placed implants. A CAD/CAM provisional crown will be delivered immediately, and the final prosthesis will be placed after 3 months.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Control group | Experimental | Procedure: No GraftingFully guided immediate implant placement with an ungrafted peri-implant jumping gap and immediate CAD/CAM provisionalization. |
| Study Group 1 (Si-β-TCP Putty Group) | Experimental | Procedure: Silicate-Added β-TCP PuttyFully guided immediate implant placement with a peri-implant jumping gap filled using silicate-added β-TCP putty and immediate CAD/CAM provisionalization. |
| Study Group 2 (Extended Sticky Bone Group) | Experimental | Procedure: Extended Sticky BoneFully guided immediate implant placement with a peri-implant jumping gap filled using extended sticky bone and immediate CAD/CAM provisionalization. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Patients with non-restorable teeth in maxillary esthetic zone requiring dental extraction.
- Age range: from18 to 50 years.
- Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration.
- Jumping gap more than 2mm.
- Patients with good oral hygiene.
Key exclusion criteria (7 listed)
- Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement.
- Alcohol or drug abuse.
- Smokers.
- Patients with systemic diseases that absolutely contraindicate implant placement (bleeding disorders, immunosuppression,…etc.)
- Pregnancy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No GraftingThe peri-implant jumping gap was managed without grafting. | Procedure or surgery | Control group |
| Silicate-Added β-TCP PuttyThe peri-implant jumping gap was managed using silicate-added β-TCP putty. | Procedure or surgery | Study Group 1 (Si-β-TCP Putty Group) |
| Extended Sticky BoneThe peri-implant jumping gap was managed using extended sticky bone. | Procedure or surgery | Study Group 2 (Extended Sticky Bone Group) |
Primary outcome
Implant Stability
Time frame: Immediate post-operative, 3 months, and 6 months.
Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values).
Hard Tissue (Peri-implant bone)
Time frame: - Immediately after implant placement - 6 months after implant placement.
Marginal bone loss will be assessed using CBCT measured in mm.
1 secondary outcome
Soft Tissue
Time frame: Baseline, 1 month, 3 months, and 6 months.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2026.
- Individual participant dataSharing planned: No
Related trials for Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing No Grafting, Silicate-Added β-TCP Putty and Extended Sticky Bone in people with Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement and Guided Immediate Implant Placement, run by Mansoura University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Implant Stability (time frame: Immediate post-operative, 3 months, and 6 months.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2026.