Clinical trials: Mind Mapping
Parkinson Disease, REM Sleep Behavior Disorder
Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls
Prospective, single center study to determine whether the current R2* iron mapping method for measuring nigral iron changes in the brain can be significantly improved by using the Quantitative Susceptibility Mapping (QSM) based…
- Conditions
- Parkinson Disease, REM Sleep Behavior Disorder, Healthy
- Trial name
- NCT03675282
- Testing
- (11C)PE2I, Ioflupane
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Autistic Disorder, Autism, Early Infantile
Using the Digital EEG Spectral Analysis in Assessing Neuroelectrical Processing Abnormalities in Autism
Individuals with Autism Spectrum Disorder will have abnormal DESA® results. Our objective is to use neuroelectrical measures to determine the degree of processing abnormalities in individuals with Autism.
- Conditions
- Autistic Disorder, Autism, Early Infantile, Autism, Infantile, Asperger Syndrome
- Trial name
- NCT00693953
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yellen & Associates, Inc.
Physicians' Knowledge and Diagnostic Practices for PGD in Older Adults, Effect of Brief Training on PGD Diagnosis
Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and Practice
Background: Prolonged Grief Disorder (PGD) is a psychiatric diagnosis with significant implications for individuals and society.
- Trial name
- PGD (NCT07487233)
- Testing
- PGD Informational Video, Bereavement Educational Video
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Ruppin Acdemic Center
Well-being, Depression
Differential Effect of Four Mindfulness Exercises
Mindfulness can be considered as a family of complex attentional and emotional regulation strategies that promote the cultivation of well-being and emotional balance.
- Conditions
- Well-being, Depression, Anxiety
- Trial name
- NCT02191553
- Testing
- Control group relaxation techniques, Loving-kindness meditation, Body scan
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress - Child Outcomes
This study is a sub-study of Mapping Antenatal Maternal Stress (MAMS). Women previously enrolled in MAMS, their children and their partners/spouses were recruited for a set of more comprehensive assessments to characterise early…
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS-CO (NCT07432243)
- Where
- Singapore
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Treatment Resistant Depression
PCS in Severe Treatment Resistant Depression
This research study is designed to test if electrical stimulation of the surface of the brain in the frontal region will help treat depressive symptoms.
- Trial name
- NCT04124341
- Testing
- Prefrontal Cortical Stimulation (PCS)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Treatment Resistant Depression, Epilepsy
Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing
The overall goal of this study is to map the spatiotemporal dynamics of social affective processing and to examine selective modulation of these dynamics in humans undergoing invasive intracranial monitoring for…
- Trial name
- NCT05418894
- Testing
- Device: Directional Deep Brain Stimulation
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
AIDS Dementia Complex
Ferumoxytol-enhanced Imaging and Mapping in neuroAIDS
This project will investigate the ability of a novel MRI contrast agent to identify and quantitate ongoing monocyte/macrophage (M/MΦ)-mediated inflammation in the brains of HIV-infected individuals.
- Trial name
- NCT02678767
- Testing
- Ferumoxytol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beau Nakamoto
Periodontitis, Alzheimer Disease
Oral Bacterial and Viral Mapping by Dental Plaque in Elderly Patients With and Without Alzheimer's Disease(ORal MICrobiology in Alzheimer's Patients)
The neurological disorders that accompany aging represent a major public health problem. The management of these diseases is a major medical and social priority.
- Trial name
- ORAMICAL (NCT04869904)
- Testing
- dental and plaque sampling
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Neurodevelopmental Disorder (Diagnosis)
Expanding NGS Data with Optical Genome Mapping (OGM)
Over 50% of pediatric neurological and neurodevelopmental disorders lack a molecular diagnosis after standard DNA sequencing and molecular karyotyping.
- Trial name
- OGM (NCT06851377)
- Testing
- Optical Genome Mapping (OGM) and Whole Genome Sequencing (WGS), Trascriptome analysis
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Obesity (Disorder), Obesity & Overweight
Dramatherapy for Psychological and Social Well-Being in Obesity and Bariatric Care
Obesity is currently a major public health challenge in France, particularly in the Hauts-de-France region, where prevalence exceeds 20% of the adult population.
- Conditions
- Obesity (Disorder), Obesity & Overweight, Eating Disorders, Bariatric Surgery
- Trial name
- NCT07685483
- Testing
- Adapted Physical Activity, Dramatherapy
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Universite du Littoral Cote d'Opale
ADHD
Managing Young People With ADHD in Primary Care Study
Background: Attention deficit hyperactivity disorder (ADHD) is the most common childhood neurodevelopmental disorder. It affects around 5% of children and adolescents, and up to 40% continue to experience symptoms into adulthood.
- Trial name
- MAP (NCT05518435)
- Testing
- None, observational study
- Where
- United Kingdom
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Alzheimer's Disease
Longitudinal Quantitative Susceptibility Mapping (QSM) in Alzheimer 's Disease
In this explorative longitudinal study 50 patients with Alzheimer's disease (AD) and 50 age-matched control subjects will be recruited for their 2 years follow-ups and undergo extensive cognitive testing and quantitative 3 Tesla…
- Trial name
- NCT02752750
- Testing
- MRI
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Huntington Disease
Clinicopathological MRI and CSF Correlates in Huntington's Disease.
In this study the investigators will link brain iron levels obtained from quantitative susceptibility maps of HD patients with specific and well-known clinical CSF markers for iron accumulation, neurodegeneration and…
- Trial name
- NCT05534139
- Testing
- 7T MRI-scan, CSF collection via lumbar puncture, Blood withdrawal
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Brain Metastases, Meningiomas
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
Background Stereotactic Radiosurgery (SRS) is a localised radiotherapy treatment for patients with brain metastases or other benign tumours in the brain, like meningiomas.
- Conditions
- Brain Metastases, Meningiomas, Stereotactic Radiosurgery, Cognitive Decline
- Trial name
- CoDeB-Rad (NCT06466720)
- Testing
- Neurocognitive testing, Quality of Life questionnaire, Stereotactic radiosurgery
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Nottingham
Alzheimer Disease, Dementia
Efficacy of Gamification in Enhancing User Engagement
As part of Phase II of the NIH SBIR grant, the study will conduct a randomized controlled clinical trial in which the MapHabit system's gamification is investigated to determine whether the assistive technology facilitates user…
- Conditions
- Alzheimer Disease, Dementia, Gamification, Assistive Technology
- Trial name
- NCT05422339
- Testing
- The MapHabit system (MHS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MapHabit, Inc.
Depressive Episode, Major Depressive Disorder
Pre-mapping Networks for Brain Stimulation 2
The investigators compare the primary and secondary outcome measures using accelerated intermittent theta burst stimulation (aiTBS, 20 sessions active and 20 sessions sham in a counterbalanced crossover design) to treat…
- Trial name
- PreNeSt2 (NCT05260086)
- Testing
- Neuronavigated aiTBS
- Where
- Germany
- Volunteers
- 92 people
- Sponsor
- University Medical Center Goettingen
Mental Health Care
Process Mapping to Optimize Child Psychosocial Screenings in Primary Care, and Increase Family Service Linkages
Many families screened in primary care for social challenges to identify psychosocial needs of caregivers and children do not receive the follow-up support they need.
- Trial name
- CARELOOP (NCT06989476)
- Testing
- CARELOOP Intervention
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of Colorado, Denver
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Phenotype in Adults With Phelan-McDermid Syndrome
The protocol aims to comprehensively define the phenotype of Phelan-McDermid Syndrome and to identify potential genetic factors, which may play a role in the variability of the disease's outcomes.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT03426059
- Testing
- No Intervention
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- Boston Children's Hospital
Total Knee Arthroplasty
The Effect of Mind Mapping-Based Education on Postoperative Pain, Kinesiophobia, and Discharge Readiness in Patients Undergoing Total Knee Arthroplasty
Total knee arthroplasty is a surgical procedure used to relieve pain and improve function in patients with severe knee joint problems.
- Trial name
- NCT07885449
- Testing
- Mind Mapping-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University