Clinical trials: Micropulse Laser
Diabetic Macular Edema
Treatment of Diabetic Macular Edema With Aflibercept and Micropulse Laser
The goal of this pilot study is to investigate the safety and efficacy of micropulse (MP) macular laser in combination with intravitreal aflibercept for the treatment of centre-involved diabetic macular edema.
- Trial name
- DAM (NCT03143192)
- Testing
- Micropulse Laser
- Where
- 2 sites in Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Keyvan Koushan
Diabetic Macular Edema
Aflibercept Plus Micropulse Laser Versus Aflibercept Monotherapy for Diabetic Macular Edema
Purpose: To evaluate the role of adjuvent micropulse laser with Aflibercept injections in the management of treatment naïve centre involving DME, looking at decreased treatment burden and increased efficacy as outcomes.
- Trial name
- NCT04014556
- Testing
- micropulse laser, Aflibercept
- Volunteers
- 40 people
- Sponsor
- University of Alexandria
Glaucoma, Glaucoma Eye
MicroPulse TLT - UK Study
This Prospective Interventional Study will assess the efficacy of MPTLT in the UK.
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle, Glaucoma Secondary
- Trial name
- MPTLTUKS (NCT05593354)
- Testing
- Micropulse Transscleral laser therapy
- Volunteers
- 250 people
- Sponsor
- Imperial College Healthcare NHS Trust
Retinitis Pigmentosa (RP)
Subthreshold Micropulse Laser Therapy (SML) in Retinitis Pigmentosa
Introduction Retinitis pigmentosa (RP) is the most common form of genetic retinal degenerative disease. The disease is progressive and leads to blindness and permanent disability within a few years of diagnosis.
- Trial name
- NCT07088705
- Testing
- SML 577 nm, SML 810 nm
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Marta P. Wiącek
Diabetic Macular Edema
Short-pulse Subthreshold vs Infrared Micropulse for Diabetic Macular Edema
When applied according to manufacturer recommendations, short-pulse system may yield more temporary reduction in edema while infrared micropulse system may yield slightly better functional outcomes.
- Trial name
- NCT04505306
- Testing
- Macular Laser
- Where
- United Arab Emirates
- Volunteers
- 113 people
- Sponsor
- Moorfields Eye Hospital Centre Abu Dhabi
Diabetic Macular Edema
Outcomes of Subthreshold Laser Versus Intravitreal Injection of Ranibizumab in Diabetic Macular Edema
The aim of this study is To compare the anatomical and functional results of intravitreal( IV) injection of ranibizumab with sub threshold micropulse laser ( SML) in treatment of Diabetic macular edema (DME) both anatomically by…
- Trial name
- NCT04332133
- Testing
- laser interference,INTRAVITREAL INJECTION
- Volunteers
- 80 people
- Sponsor
- Minia University
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy and Micropulse Laser Treatment
To evaluate choroidal and choriocapillaris changes in patients with central serous chorioretinopathy, undergone sub threshold micropulse laser treatment, following any improvement with conservative therapy with Acetazolamide…
- Trial name
- LEVEO (NCT06346405)
- Testing
- Subthreshold Micropulse Laser Treatment
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Glaucoma
Laser Dosage in MicroPulse TransScleral CycloPhotocoagulation
This is a prospective study to evaluate the clinical outcome of varying doses of Micropulse TransScleral CycloPhotocoagulation (MP-TSCPC) laser in patients with glaucoma.
- Trial name
- NCT04709679
- Testing
- MicroPulse TransScleral CycloPhotoCoagulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
Uddevalla Skövde Transscleral Micropulse Study
Micro pulse transscleral laser treatment (MP-TLT) is a relatively new method to reduce the intraocular pressure (IOP) in glaucoma.
- Trial name
- USTMS (NCT05557721)
- Testing
- Topical lidocaine, MP-TLT
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (532nm) Versus Conventional Laser Trabeculoplasty (532nm)
This study will investigate if micropulse laser trabeculoplasty (532nm) is as effecttive as or better than the conventional laser trabeculoplasty (532nm), it might be a new treatment strategy for glaucoma patients.
- Trial name
- NCT01788319
- Testing
- lasertrabeculoplasty
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetic Macular Edema
Additional Effect of Subthreshold Micropulse Laser to Intravitreous Injection of Bevacizumab on Diabetic Macular Edema
In this study, all eyes with diabetic macular edema who meet the inclusion criteria and do not meet the exclusion criteria will be included.
- Trial name
- NCT05582577
- Testing
- Intravitreal bevacizumab injection with subthreshold micropulse laser, Intravitreal bevacizumab injection alone
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Glaucoma
Tear Interleukin Biomarkers After Glaucoma Treatment
This prospective study aims to evaluate inflammatory biomarkers in tear fluid in patients with glaucoma undergoing micropulse transscleral cyclophotocoagulation (MP-CPC), continuous-wave cyclophotocoagulation (CPC), and…
- Trial name
- TIGT (NCT07592988)
- Testing
- MicroPulse Transscleral Cyclophotocoagulation, Conventional Transscleral Cyclophotocoagulation, Antiglaucoma Surgery
- Where
- Kazakhstan
- Volunteers
- 24 people
- Sponsor
- Kazakh Eye Research Institute
Diabetic Macular Edema
Combination of Standard Lucentis Therapy With Micropulse Diode Laser for the Treatment of Diabetic Macular Edema
The primary objective of this study is to evaluate if a combination therapy with micropulse diode laser treatment shows non inferiority on visual acuity within 12 months in comparison to standard therapy (intravitreal injection…
- Trial name
- ReCaLL (NCT02059772)
- Testing
- ranibizumab, micropulse diode laser
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- GWT-TUD GmbH
Central Serous Chorioretinopathy
Panmacular Versus Minimal Micropulse Laser Therapy in Central Serous Chorioretinopathy
Central serous retinopathy is a disease of poorly understood etiology characterized by accumulation of subretinal fluid and leading to significant decrease in vision.
- Trial name
- NCT04410861
- Testing
- Micropulse laser photostimulation
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Moorfields Eye Hospital Centre Abu Dhabi
Glaucoma
Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients
The purpose of this study is to evaluate the clinical outcomes of the Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) after 1 day, 1 week,1 month, 3 months, 6 months and one year of follow-up, with the intent to…
- Trial name
- NCT05654493
- Testing
- MicroPulse Transscleral Laser Therapy using revised P3 Delivery Device
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Mayo Clinic
Conjunctiva, Cornea
MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface
MicroPulse transscleral laser therapy (TLT) is proven to be effective in reducing intraocular pressure with minimal complications in either primary or secondary glaucoma.
- Trial name
- NCT06353776
- Testing
- conjunctival biopsy after micropulse transscleral laser therapy
- Where
- Tunisia
- Volunteers
- 15 people
- Sponsor
- University Tunis El Manar
Central Serous Chorioretinopathy, Micropulse Laser
Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included.
- Conditions
- Central Serous Chorioretinopathy, Micropulse Laser, Photodynamic Therapy
- Trial name
- NCT06468540
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital
Diabetic Macular Edema
Micropulse 810 Nanomolar (nm), Diode Laser for Diffuse Diabetic Macular Edema
Objective: To compare micropulse 810nm diode laser photocoagulation versus argon laser photocoagulation for treatment of diabetic macular edema.
- Trial name
- NCT00552435
- Testing
- Laser photocoagulation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Acute Central Serous Retinopathy With Subretinal Fluid
Subthreshold Micropulse Laser Treatment of Acute Central Serous Chorioretinopathy
To evaluate the efficacy and safety of 532 nm green subthreshold micropulse laser (GSML) as a treatment for acute central serous chorioretinopathy (CSCR).
- Trial name
- NCT05447117
- Testing
- Micropulse laser
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Minia University
Dry Eye, Dry Eye Syndromes
Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland Dysfunction
The modern treatment of meibomian gland dysfunction(MGD) is based on anti-inflammatory drops or oral antibiotics for decreasing dry eye disease (DED) associated inflammation, warm compresses for liquefying the thicker meibum, and…
- Conditions
- Dry Eye, Dry Eye Syndromes, Meibomian Gland Dysfunction
- Trial name
- NCT04425551
- Testing
- laser light
- Where
- 2 sites in Greece
- Volunteers
- 30 people
- Sponsor
- Naval Hospital, Athens