Clinical trials: Methamphetamine Use
Methamphetamine Use Disorder, Methamphetamine Induced Psychosis
ECG Findings in Methamphetamine Use
This prospective cohort study aims to examine and compare electrocardiogram (ECG) parameters in subjects diagnosed with Methamphetamine Use Disorder (MUD) and Methamphetamine-Induced Psychotic Disorder (MP) during inpatient…
- Trial name
- NCT07459244
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Methamphetamine Induced Psychosis, Cannabis Use
Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use
This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU).
- Trial name
- NCT07459270
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
PrEP Adherence, Methamphetamine Use Disorder
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use…
- Conditions
- PrEP Adherence, Methamphetamine Use Disorder, HIV
- Trial name
- CHAMPION (NCT07213258)
- Testing
- CHAMPION Intervention, Delayed CHAMPION Package
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Obesity, Methamphetamine Use Disorder
An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder
This open label pilot study will assess the feasibility and preliminary efficacy of tirzepatide which will be prescribed under its FDA approved weight management indication in adults with moderate or severe methamphetamine…
- Conditions
- Obesity, Methamphetamine Use Disorder, Cocaine Use Disorder, Stimulant Use Disorders
- Trial name
- TRI-MR (NCT07693608)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Texas Southwestern Medical Center
Methamphetamine Use Disorder, Substance Use Disorder
Closed-loop TMS for the Core Clinical Features of the Methamphetamine Use Disorder
The goal of this clinical trial is to evaluate whether closed-loop transcranial magnetic stimulation (TMS) can improve core clinical symptoms in individuals with methamphetamine use disorder (MUD), such as cue-reactivity and…
- Conditions
- Methamphetamine Use Disorder, Substance Use Disorder, Cue-reactivity, Craving
- Trial name
- NCT07154160
- Testing
- Closed-loop TMS, Conventional TMS, Random TMS
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Shanghai Mental Health Center
Opioid Use Disorder, Methamphetamine Abuse
Contingency Management for Drug Use: Does Age Matter?
The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives.
- Conditions
- Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
- Trial name
- NCT05521854
- Testing
- DynamiCare app (app-based contingency management)
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University Health Sciences
HIV -1 Infection, Methamphetamine Use
Short-term Effects of Methamphetamine on Residual Latent HIV Disease Study
The most commonly used illicit stimulant in people with HIV (PWH) is methamphetamine (MA). Prior studies demonstrate strong evidence that MA promotes increased HIV transcription as well as immune dysregulation.
- Trial name
- EMRLHD (NCT07584369)
- Testing
- Oral Methamphetamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Methamphetamine Use Disorder
Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV
The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients…
- Trial name
- KARE (NCT06538285)
- Testing
- Ketamine, Psychotherapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nicky Mehtani, MD, MPH
Methamphetamine Use Disorder, Human Immunodeficiency Virus (HIV)
Psilocybin Therapy for Methamphetamine Use Disorder and HIV
The goal of this clinical trial is to learn whether it is possible to use psilocybin in combination with motivational support therapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in people with HIV who are…
- Trial name
- PRISM (NCT07756736)
- Testing
- Psilocybin 5 mg, Psilocybin 25 mg, Motivational Support
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nicky Mehtani, MD, MPH
Methamphetamine Use Disorders, HIV
Transcranial Magnetic Stimulation for Methamphetamine Use Disorder in PLWH
The purpose of this study is to learn more about how accelerated theta burst stimulation affects methamphetamine craving and brain activity.
- Trial name
- NCT06830980
- Testing
- intermittent theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Gopalkumar Rakesh
Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers
Effectiveness of Stress Management Training Program For Expressed Emotions in Caregivers of Drug Induced Psychosis Patients Specially Methamphetamine
The main purpose of this study is to evaluate the effectiveness of a Stress Management Training (SMT) program in reducing stress levels among caregivers of individuals suffering from methamphetamine ("ice") addiction and…
- Conditions
- Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers, Stress Cause Expressed Emotion and Burden
- Trial name
- NCT07714642
- Testing
- O'Connor's (2003) Stress Management Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Methamphetamine Use Disorder
Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study
Methamphetamine use disorder is a major public health concern in Australia and globally. GLP-1 medications such as semaglutide (e.g.
- Trial name
- SHIFT (NCT07509112)
- Testing
- 12 weeks of weekly subcutaneous semaglutide injection
- Where
- 5 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Kirby Institute
Methamphetamine Use Disorder
Cerebellum-Prefrontal Paired-Pulse Stimulation for Methamphetamine Use Disorder
To investigate the mechanism and efficacy of a novel repetitive transcranial magnetic stimulation (rTMS) intervention model with paired cerebellar-medial prefrontal cortex (mPFC) pulses on methamphetamine use disorder patients…
- Trial name
- NCT06457230
- Testing
- Paired Associative Stimulation Targeting the Cerebellar-mPFC
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Use Disorder
Methamphetamine and Troriluzole
This will be a human laboratory study evaluating the influence of troriluzole treatment on the effects of methamphetamine. Supported by and included in the Helping to End Addiction Long-term® (HEAL) Initiative.
- Trial name
- BED IN 46 (NCT06989853)
- Testing
- Methamphetamine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- William Stoops
Methamphetamine Use Disorder
Non-Abstinence Outcomes in Methamphetamine Use Disorder
Reduced drug use is a clinically meaningful target for treatment development, but few studies have evaluated the positive impacts produced by this behavioral change, preventing adoption of this endpoint in clinical trials.
- Trial name
- RCT (05) (NCT07226596)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- William Stoops
Methamphetamine Use Disorder, Substance-Related Disorders
Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder
The purpose of this research study is to investigate the safety and feasibility of two (2) oral doses of psilocybin when combined with behavioral support for methamphetamine use disorder (MUD).
- Conditions
- Methamphetamine Use Disorder, Substance-Related Disorders, Chemically-Induced Disorders, Substance Use Disorders
- Trial name
- NCT05322954
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Wisconsin, Madison
Heart Failure, Methamphetamine Use Disorder
Methamphetamine Use Disorder Support in Heart Failure Pilot Study
Heart failure (HF) affects over 6 million people in the US and is a major cause of both hospital admissions and death. HF has many causes and contributing factors.
- Trial name
- Meth-HF (NCT07211724)
- Testing
- MUD Management (contingency management +/- adjunctive MUD pharmacotherapy), HF GDMT management
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Stimulant Use Disorder, Cocaine Use Disorder
LDART for Stimulant Use Disorder
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a digital intervention called LDART in adults with stimulant use disorder.
- Conditions
- Stimulant Use Disorder, Cocaine Use Disorder, Methamphetamine Use Disorder
- Trial name
- LDART (NCT07221396)
- Testing
- LDART, Psychoeducational booklet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Methamphetamine Use Disorder, Methamphetamine-induced Psychosis
α-N-acetylgalactosaminidase in Methamphetamine Psychosis
This cross-sectional observational cohort study examined serum α-N-acetylgalactosaminidase levels in methamphetamine use disorder (MUD), methamphetamine-induced psychotic disorder (MP), and healthy control (HC) groups.
- Trial name
- NCT07434401
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Methamphetamine Abuse, Methamphetamine-dependence
Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is becoming an increasing public health concern in Canada. While the evidence on the efficacy and safety of prescription psychostimulants for the treatment of MUD is promising, the knowledge on…
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance Abuse
- Trial name
- NCT06788587
- Testing
- LDX-01 plus TAU
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)