Clinical trials: Metabolic Health
M-health, Metabolic Syndrome
Exercise-Targeted Smart Lifestyle Management
To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight/obesity and metabolic…
- Conditions
- M-health, Metabolic Syndrome, Lifestyle Alteration, Lifestyle (Sedentary Behavior and Physical Activity)
- Trial name
- NCT07535333
- Testing
- Dietary Prescription, Personalized Exercise Prescription, Metabolic Syndrome Prevention and Education
- Volunteers
- 435 people
- Sponsor
- China National Center for Cardiovascular Diseases
Insomnia, Metabolic Health
Treating Insomnia and Improving Metabolic Health in Midlife Women With Insomnia
The aim of this study is to determine if suvorexant can help treat the severity of insomnia and improve metabolic health in midlife women who had both insomnia and indicators of metabolic syndrome.
- Conditions
- Insomnia, Metabolic Health, Menopause
- Trial name
- NCT05593653
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Brigham and Women's Hospital
Metabolic Health
ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks
The purpose of this study is to determine the impact of real-world shiftwork on metabolic flexibility.
- Trial name
- COMET (NCT05820490)
- Testing
- Whole Room Calorimeter, Mixed-Meal Tolerance Test (MMTT), Core Body Temperature
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Environmental Exposure, Fertility
JiGenerations Health Cohort Study：Parental Exposure and Intergenerational Health in China
The growing recognition of maternal health's impact on offspring necessitates large-scale prospective cohort studies spanning the maternal-child life cycle.
- Conditions
- Environmental Exposure, Fertility, Health Problems in Pregnancy, Adverse Pregnancy Outcomes
- Trial name
- NCT07514377
- Testing
- N/A (Observational Study)
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Appetite, Circadian Rhythm
Time-restricted Feeding and Health
The purpose of this pilot, single-arm clinical trial is to assess the effects of time-restricted feeding on overall health, including body composition, glycemic and lipidemic profile, as well as appetite-regulating hormones…
- Conditions
- Appetite, Circadian Rhythm, Metabolic Health, Body Weight Control
- Trial name
- e-TRF (NCT07505680)
- Testing
- Time-Restricted Feeding
- Where
- Greece
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Food Acceptance, Metabolic Health
Impact of Protein Source and Polyphenol Complexation in Protein Bars on Metabolic Health
The goal of this clinical trial is to learn if pulse (pea) protein works similar to animal (whey) protein in protein bars consumed by healthy adults.
- Conditions
- Food Acceptance, Metabolic Health, Immune Cells Activity, Microbiome Composition
- Trial name
- POLYPRO (NCT07489118)
- Testing
- Whey protein bar, Pea protein bar, Pea protein with complexed polyphenols bar
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Exercise, Overreaching
Impact of Training Load on the Gut miCrobiome And Its Relation to exeRcise Performance, mUscle Phenotype, and markerS of Overreaching in Healthy Men
The goal of this study is to learn how different amounts of supervised indoor cycling training change gut health (gut bacteria, the substances gut bacteria make, and the gut barrier integrity), and how these changes relate to…
- Conditions
- Exercise, Overreaching, Butyrate, Gut Microbiome
- Trial name
- ICARUS (NCT07481578)
- Testing
- Supplement, Moderate load exercise training, High load exercise training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stefan De Smet
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Type 2 Diabetes, Metabolic Health
Effect of Prebiotics in Saudi Adults With Type 2 Diabetes
This study will explore how a natural food ingredient called oligofructose affects blood glucose levels, lipid profiles, inflammation biomarkers, and gut bacteria in Saudi adults with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Metabolic Health, Inflammation, Gut Microbiome
- Trial name
- NCT07464691
- Testing
- oligofructose
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Dairy Consumption, Metabolic Health
The Effect of Dairy Intake on Body Weight and Composition and Metabolic Health in Adolescents and Seniors
The goal of this study is to examine how regular dairy intake affects body weight, body composition, and metabolic health in overweight and obese adolescents (ages 15-18) and older adults (ages 60-80) over six months.
- Conditions
- Dairy Consumption, Metabolic Health, Obesity Prevention
- Trial name
- NCT06879652
- Testing
- Counselling to follow Canada's Food Guide and 3 daily servings of Dairy (long-term study), Dairy (short-term study), Counselling to follow Canada's Food Guide (long-term study)
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Toronto
Metabolic Health
Metabolic Health 1: Power Line Evaluation; Effect Size Determination
The primary goal of this study is to demonstrate the safety and tolerability of the Power Line program, an integrated, whole-food supplement system.
- Trial name
- NCT06486077
- Testing
- Power Line Program
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nature's Sunshine Products, Inc.
Metabolic Health
Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring
The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.
- Trial name
- NCT07435857
- Testing
- exercise
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Peking University First Hospital
Overweight/Obesity, Metabolic Health
Composite Dietary Antioxidant Index and Metabolic Health in Overweight/Obesity in U.S. Adults
This cross-sectional study draws on data from the National Health and Nutrition Examination Survey (NHANES) database. The primary objective is to investigate the associations between the Composite Dietary Antioxidant Index (CDAI)…
- Trial name
- NCT07291726
- Testing
- None (Observational)
- Where
- China
- Sponsor
- University-Town Hospital of Chongqing Medical University
Cardiovascular Diseases, Metabolic Health
Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project
The purpose of this study is to examine how the environment and neighborhood characteristics affects the health of the area residents.
- Trial name
- HEAL (NCT03670524)
- Testing
- Greenness as a therapeutic intervention
- Where
- United States
- Volunteers
- 835 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Metabolic Diseases, Neurological and Mental Health Conditions
Growing Up in Singapore Towards Healthy Outcomes
This study aims to examine the role of genetic and epigenetic factors, maternal nutrition, lifestyle, emotional health, and other environmental factors in pregnancy or postpartum period that can influence future maternal risk of…
- Conditions
- Metabolic Diseases, Neurological and Mental Health Conditions, Genetic Predisposition, Skin Condition
- Trial name
- GUSTO (NCT01174875)
- Where
- Singapore
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Overweight, Metabolic Health
Study to Evaluate the Efficacy of an Avocado Dietary Supplement
This 16-week, randomized, triple-blinded, placebo-controlled study evaluates the effects of an avocado dietary supplement (Metavo) on healthy weight and blood glucose management in overweight adults.
- Conditions
- Overweight, Metabolic Health, Insulin Resistance
- Trial name
- METAVO-ONE (NCT07354308)
- Testing
- Metavo Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SP Nutraceuticals Inc.
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Truway Diagnostic Tools in Primary Care
This study evaluates the effectiveness of Truway Health-sourced portable diagnostic devices, including ultrasound and blood glucose monitors, in early detection of chronic conditions in outpatient primary care settings.
- Conditions
- Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute
- Trial name
- TruDxPC (NCT07209527)
- Testing
- Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Cancer, Mental Health
Healthspan Connect Programme of Research
Healthspan Connect is a new research programme designed to understand what helps people stay healthy as they age. The programme will explore how lifestyle, environment, genetics, and social factors influence healthy ageing and…
- Conditions
- Cancer, Mental Health, Ageing Well, Resilience
- Trial name
- NCT07209774
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- King's College London
Metabolic Health, Fruit and Vegetable Intake
Comparing Approaches to Increasing Fruit and Vegetable Intake and Their Influence on Metabolic Health
This experimental study aims to evaluate the effects of different strategies for increasing fruit and vegetable intake and to see how these interventions influence markers of health in people aged 18-65 who currently consume…
- Trial name
- NCT06628401
- Testing
- Educational information (Control), Educational information (Increasing F&V intake), Educational information (Increasing F&V intake + Juice)
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Courtney Neal