Clinical trials: Metabolic Health
Cardio-metabolic Health
Peer-modeled Intervention
The goal of this clinical trial is to learn about the effects of a peer-led behavioural change intervention on the cardio-metabolic health of women aged 18 to 49 years.
- Trial name
- NCT07476716
- Testing
- A peer-modelled behavioural change intervention
- Where
- Uganda
- Volunteers
- 157 people
- Sponsor
- KU Leuven
PreDiabetes, Adolescent Obesity
SMART GOALS for Youth With Prediabetes
The goal of this study is to compare the impact of a SMART ((specific, measurable, attainable, realistic, or timely) Goal setting protocol on body weight, metabolic parameters (Hemoglobin A1c, lipids), diet quality and physical…
- Conditions
- PreDiabetes, Adolescent Obesity, Behavior, Health, Nutritional and Metabolic Diseases
- Trial name
- NCT06067451
- Testing
- SMART GOALS Setting Tool/ Protocol
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Northwell Health
Metabolic Disorder, Sub-health Status
Effects of a 12-Week Solid Beverage Intervention on Suboptimal Health Status
This is a randomized, double-blind, placebo-controlled clinical trial targeting Chinese overweight/obese subjects aged 18-60 years with mild metabolic abnormalities.
- Trial name
- NCT07884643
- Testing
- Meta Solid Beverage A, Meta Solid Beverage B
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Cardiovascular (CV) Risk, Metabolic Health
Advancing Health Equity and Preventive Cardiovascular Care in Indigenous and Remote Communities: a Mobile Healthcare Unit
Indigenous people living in Canada face significant healthcare inequities, particularly in basic, primary, and secondary prevention, leading to higher rates of cardiovascular disease and mortality.
- Conditions
- Cardiovascular (CV) Risk, Metabolic Health, Primary Prevention
- Trial name
- NCT07869069
- Testing
- Cardiovascular risk screening, Follow-up of cardiovascular risk factors
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laval University
Dietary Assessment, Dietary and Lifestyle Behaviour Change
BRE-13: Mediterranean Diet
Explore the effect of MedDiet vs. Usual Diet on circulating and breast tumor fatty acid profiles. The investigators aim to examine impact on tumor biology in newly diagnosed participants.
- Conditions
- Dietary Assessment, Dietary and Lifestyle Behaviour Change, Dietary Behavior, Metabolic Health
- Trial name
- BRE-13 (NCT07869355)
- Testing
- Explore the effect of MedDiet vs. Usual Diet on Fatty Acid Profile, Explore the effect of MedDiet vs. Usual Diet on Breast Tumor Tissue, Explore the effect of MedDiet vs. Usual Diet on Lipids
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Metabolic Health, Musculoskeletal Disorders (MSDs)
SUSTAINA Study: Effects of Sustainable Diet and Therapeutic Exercise on Health in Young Athletes
The SUSTAINA study aims to evaluate the effects of sustainable dietary programs combined with individualized therapeutic exercise on metabolic health, body composition, and musculoskeletal function in young athletes.
- Conditions
- Metabolic Health, Musculoskeletal Disorders (MSDs), Physical Fitness, Body Composition
- Trial name
- SUSTAINA (NCT07567066)
- Testing
- Behavioral: Nutritional Intervention, Conventional Strength Training, Explosive Strength Training
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Fasting Conditions, Metabolic Health
Effects of the Buchinger Wilhelmi Fasting Program and Exercise on Physical Fitness and Sleep Quality
Type of Study: Clinical Trial Goal: The goal of this clinical trial is to investigate whether combining the Buchinger Wilhelmi prolonged fasting program with a structured exercise program can improve physical fitness, body…
- Trial name
- FASTEX (NCT07847658)
- Testing
- Buchinger Wilhelmi prolonged fasting, Online exercise program, Supervised exercise program during prolonged fasting
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Cardiorespiratory Fitness, Metabolic Health
Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults
The purpose of this single-group diagnostic validation and test-retest reliability study is to determine whether a novel Incremental Step Test (IST) can accurately assess cardiorespiratory fitness and ventilatory thresholds in…
- Conditions
- Cardiorespiratory Fitness, Metabolic Health, Cardiac Function, Pulmonary Function
- Trial name
- VALID-IST (NCT07829003)
- Testing
- Cardiopulmonary Exercise Test, Incremental Step Test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Respiration Disorders, Body Composition, Beneficial
The Austrian LEAD (Lung hEart sociAl boDy) Study
The LEAD study is the first longitudinal cohort investigating respiratory, cardiac, and metabolic health in a reference population of Austria.
- Conditions
- Respiration Disorders, Body Composition, Beneficial, Metabolic Health
- Trial name
- LEAD (NCT01727518)
- Testing
- As the LEAD study is an observational cohort study, there is no intervention to report.
- Where
- Austria
- Volunteers
- 14,966 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute for Lung Health
Healthy Aging, Inflammaging
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
The goal of this clinical trial is to learn if Quercefit® or Ubiqsome™ can improve markers of healthy aging, blood sugar control, and heart health in older adults. It will also learn about the safety of these supplements.
- Conditions
- Healthy Aging, Inflammaging, Metabolic Health, Quercetin
- Trial name
- NCT07760506
- Testing
- Quercetin (dietary supplement), Coenzyme Q10, Rice Flour
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk
Agentic AI Personalized Dietary Management Study
This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening.
- Trial name
- AIDiet (NCT07638241)
- Testing
- Static AI-based personalized dietary goal setting, Adaptive AI-based personalized dietary management
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Metabolic Health
Radicle HealthTM VIP: A Study Assessing the Impact of Health and Wellness Products on Metabolic Health and Related Health Outcomes
Radicle HealthTM VIP: A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on metabolic health and related health outcomes.
- Trial name
- NCT07819110
- Testing
- Active Metabolic Product 1
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland
Metabolic Health
Women's Hormonal and Metabolic Wellbeing Study
The goal of this clinical trial is to learn if Daily Nouri Hormone Balance Probiotic blend can improve metabolic, inflammatory, and symptom outcomes in women.
- Trial name
- NCT07268404
- Testing
- Probiotic Blend Capsule
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Daily Nouri
Metabolic Health, Insulin Sensitivity/Resistance
Defining the Human Insulin Resistance Molecular Network; SIGNATURE
The goal of this intervention study is to learn more about what causes insulin resistance in otherwise healthy adults, and how short-term changes in physical activity or diet may influence it.
- Trial name
- SIGNATURE (NCT07255807)
- Testing
- Physical Inactivity, Hypercaloric High-Fat Diet
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen