Metabolic HealthSUSTAINANCT07567066
SUSTAINA Study: Effects of Sustainable Diet and Therapeutic Exercise on Health in Young Athletes
A study testing Behavioral: Nutritional Intervention, Conventional Strength Training and Explosive Strength Training in people with Metabolic Health and Musculoskeletal Disorders (MSDs), run by University of Alicante at 1 site in Spain.
Trial summary
The SUSTAINA study aims to evaluate the effects of sustainable dietary programs combined with individualized therapeutic exercise on metabolic health, body composition, and musculoskeletal function in young athletes. Read more about this study
- Who is it for?
- Ages 14 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Metabolic Health, Musculoskeletal Disorders (MSDs), Physical Fitness
- What is being tested?
- Behavioral: Nutritional Intervention, Conventional Strength Training and Explosive Strength Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteSpain
- Study dates
- 1 Jan 2026to 30 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 25 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Age between 14 and 25 years
- Regular participation in organized physical activity (≥4 days per week)
- Healthy individuals without diagnosed metabolic or musculoskeletal disorders
- Ability to participate in physical exercise programs
- Written informed consent provided by the participant or legal guardian (for minors)
Who cannot join
- Presence of diagnosed metabolic disease (e.g., diabetes, cardiovascular disease)
- Musculoskeletal injury or condition that prevents participation in exercise
- Any medical condition contraindicating physical activity
- Use of medication or treatment that may affect metabolic or physical performance outcomes
- Failure to comply with study procedures or intervention protocols
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Research and Development of New Sustainable Dietary and Nutritional Programs and Therapeutic Exercise for the Prevention of Metabolic and Musculoskeletal Disorders
The SUSTAINA study aims to evaluate the effects of sustainable dietary programs combined with individualized therapeutic exercise on metabolic health, body composition, and musculoskeletal function in young athletes. Participants will be randomly assigned to different intervention groups receiving tailored exercise training and nutritional guidance based on Mediterranean diet principles. The study will assess physiological, anthropometric, and functional outcomes to identify effective strategies for preventing metabolic and musculoskeletal disorders.
Read the detailed description
This study is a randomized controlled trial designed to investigate the impact of combined dietary and exercise interventions on health outcomes in young athletes. Participants will be allocated into different groups, including a control group and intervention groups receiving structured therapeutic exercise programs and personalized nutritional strategies based on sustainable Mediterranean diet principles.
Measurements will include body composition, metabolic parameters, physical performance, and musculoskeletal function. The intervention is expected to provide evidence-based strategies to prevent metabolic and musculoskeletal disorders in physically active populations.
- Being tested
- Behavioral: Nutritional Intervention, Conventional Strength Training, Explosive Strength Training, Functional Training, Isoinertial Training
- Keywords
- Nutrition, Exercise, Mediterranean Diet, Athletes, Prevention
- Medical subject headings
- Musculoskeletal Diseases, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Behavioral: Nutritional InterventionBehavioural
Personalized dietary program based on sustainable Mediterranean diet principles, adapted to individual energy and nutritional requirements.
Conventional Strength TrainingOther
Traditional resistance training program including hypertrophy and strength-based exercises using guided machines and free weights.
Explosive Strength TrainingOther
High-intensity strength training focused on explosive movements using free weights.
Functional TrainingOther
Exercise program based on functional movements using alternative training materials.
Isoinertial TrainingOther
Resistance training program using isoinertial devices with an emphasis on eccentric load.
| Study group | Role | What they receive |
|---|---|---|
| Arm 1: Control Group | Active comparator | Nutritional intervention only (no structured exercise). Participants receive a personalized dietary intervention based on Mediterranean diet principles, without participation in a structured exercise program. Receives: Behavioral: Behavioral: Nutritional Intervention |
| Arm 2: Traditional resistance training (hypertrophy) + nutritional intervention | Experimental | Participants perform a hypertrophy-focused resistance training program combined with a personalized dietary intervention. Receives: Behavioral: Behavioral: Nutritional Intervention; Other: Conventional Strength Training |
| Arm 3: Explosive strength training + nutritional intervention | Experimental | Participants perform an explosive strength training program combined with a personalized dietary intervention. Receives: Behavioral: Behavioral: Nutritional Intervention; Other: Explosive Strength Training |
| Arm 4: Functional training + nutritional intervention | Experimental | Participants perform a functional training program using alternative materials combined with a personalized dietary intervention. Receives: Behavioral: Behavioral: Nutritional Intervention; Other: Functional Training |
| Arm 5: Isoinertial training + nutritional intervention | Experimental | Participants perform an isoinertial resistance training program combined with a personalized dietary intervention. Receives: Behavioral: Behavioral: Nutritional Intervention; Other: Isoinertial Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in fat mass
Assessment of fat mass using dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis.
Measured: Baseline to 9 months
Change in lean body mass
Assessment of lean body mass using dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis.
Measured: Baseline to 9 months
Secondary outcomes (14)
Change in blood glucose levels
Measurement of blood glucose levels using a portable biochemical analyzer.
Measured: Baseline to 9 months
Change in triglyceride levels
Assessment of triglyceride levels using a portable biochemical analyzer.
Measured: Baseline to 9 months
Change in bone mineral content
Assessment of bone mineral content using dual-energy X-ray absorptiometry (DXA).
Measured: Baseline to 9 months
Change in total cholesterol levels
Assessment of total cholesterol levels using a portable biochemical analyzer.
Measured: Baseline to 9 months
Change in handgrip strength
Assessment of upper body isometric strength using a handgrip dynamometer. Measured in kilograms (kg)
Measured: Baseline and 9 months
Change in lower body strength (countermovement jump height)
Assessment of lower body strength using countermovement jump (CMJ) height measured with a contact platform (cm).
Measured: Baseline and 9 months
Change in sprint performance
Assessment of sprint performance using 10-30 meter sprint tests measured with photocell timing systems. Measured in seconds (s)
Measured: Baseline and 9 months
Change in endurance capacity (Yo-Yo Intermittent Recovery Test Level 1)
Assessment of endurance capacity using the Yo-Yo Intermittent Recovery Test Level 1, expressed as total distance covered (meters).
Measured: Baseline and 9 months
Change in functional movement (Functional Movement Screen score)
Assessment of functional movement using the Functional Movement Screen (FMS), scored from 0 to 21 points, where higher scores indicate better movement quality and lower injury risk.
Measured: Baseline and 9 months
Change in joint range of motion
Assessment of joint range of motion using goniometric measurements.
Measured: Baseline and 9 months
Change in urine specific gravity
Assessment of hydration status using urine specific gravity measured by refractometry.
Measured: Baseline and 9 months
Change in hydration status (urine color scale)
Assessment of hydration status using a validated urine color scale ranging from 1 to 8, where lower values indicate better hydration status and higher values indicate dehydration.
Measured: Baseline and 9 months
Change in blood pressure
Measurement of systolic and diastolic blood pressure using a digital sphygmomanometer.
Measured: Baseline and 9 months
Change in basal metabolic rate
Assessment of basal metabolic rate using indirect calorimetry.
Measured: Baseline and 9 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 May 2026
- Study start1 Jan 2026
- Primary completion30 Jun 2026
- Study completion30 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Metabolic HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Alicante
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Prof. Dr. Alejandro Martínez-Rodríguez, University of Alicante
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07567066
- Sponsor's protocol ID
- UA-2026-02-19_3
- Acronym
- SUSTAINA
- Status last verified
- Apr 2026
- First submitted
- 20 Apr 2026
- Last updated
- 7 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Research and Development of New Sustainable Dietary and Nutritional Programs and Therapeutic Exercise for the Prevention of Metabolic and Musculoskeletal Disorders
- ClinicalTrials.gov ID
- NCT07567066
- Acronym / sponsor ID
- SUSTAINA / UA-2026-02-19_3
- Keywords
- Nutrition, Exercise, Mediterranean Diet, Athletes, Prevention
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 70 participants (actual)
- Lead sponsor
- University of AlicanteUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 Jun 2026 (actual)
- Study completion
- 30 Sep 2026 (estimated)
- First posted
- 5 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The SUSTAINA study aims to evaluate the effects of sustainable dietary programs combined with individualized therapeutic exercise on metabolic health, body composition, and musculoskeletal function in young athletes. Participants will be randomly assigned to different intervention groups receiving tailored exercise training and nutritional guidance based on Mediterranean diet principles. The study will assess physiological, anthropometric, and functional outcomes to identify effective strategies for preventing metabolic and musculoskeletal disorders.
Detailed description
This study is a randomized controlled trial designed to investigate the impact of combined dietary and exercise interventions on health outcomes in young athletes. Participants will be allocated into different groups, including a control group and intervention groups receiving structured therapeutic exercise programs and personalized nutritional strategies based on sustainable Mediterranean diet principles.
Measurements will include body composition, metabolic parameters, physical performance, and musculoskeletal function. The intervention is expected to provide evidence-based strategies to prevent metabolic and musculoskeletal disorders in physically active populations.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Arm 1: Control Group | Active comparator | Behavioral: Behavioral: Nutritional InterventionNutritional intervention only (no structured exercise). Participants receive a personalized dietary intervention based on Mediterranean diet principles, without participation in a structured exercise program. |
| Arm 2: Traditional resistance training (hypertrophy) + nutritional intervention | Experimental | Behavioral: Behavioral: Nutritional Intervention, Other: Conventional Strength TrainingParticipants perform a hypertrophy-focused resistance training program combined with a personalized dietary intervention. |
| Arm 3: Explosive strength training + nutritional intervention | Experimental | Behavioral: Behavioral: Nutritional Intervention, Other: Explosive Strength TrainingParticipants perform an explosive strength training program combined with a personalized dietary intervention. |
| Arm 4: Functional training + nutritional intervention | Experimental | Behavioral: Behavioral: Nutritional Intervention, Other: Functional TrainingParticipants perform a functional training program using alternative materials combined with a personalized dietary intervention. |
| Arm 5: Isoinertial training + nutritional intervention | Experimental | Behavioral: Behavioral: Nutritional Intervention, Other: Isoinertial TrainingParticipants perform an isoinertial resistance training program combined with a personalized dietary intervention. |
Who may qualify
- Ages
- 14 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Age between 14 and 25 years
- Regular participation in organized physical activity (≥4 days per week)
- Healthy individuals without diagnosed metabolic or musculoskeletal disorders
- Ability to participate in physical exercise programs
- Written informed consent provided by the participant or legal guardian (for minors)
Key exclusion criteria (5 listed)
- Presence of diagnosed metabolic disease (e.g., diabetes, cardiovascular disease)
- Musculoskeletal injury or condition that prevents participation in exercise
- Any medical condition contraindicating physical activity
- Use of medication or treatment that may affect metabolic or physical performance outcomes
- Failure to comply with study procedures or intervention protocols
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Behavioral: Nutritional InterventionPersonalized dietary program based on sustainable Mediterranean diet principles, adapted to individual energy and nutritional requirements. | Behavioural | Arm 1: Control Group, Arm 2: Traditional resistance training (hypertrophy) + nutritional intervention, Arm 3: Explosive strength training + nutritional intervention, Arm 4: Functional training + nutritional intervention, Arm 5: Isoinertial training + nutritional intervention |
| Conventional Strength TrainingTraditional resistance training program including hypertrophy and strength-based exercises using guided machines and free weights. | Other | Arm 2: Traditional resistance training (hypertrophy) + nutritional intervention |
| Explosive Strength TrainingHigh-intensity strength training focused on explosive movements using free weights. | Other | Arm 3: Explosive strength training + nutritional intervention |
| Functional TrainingExercise program based on functional movements using alternative training materials. | Other | Arm 4: Functional training + nutritional intervention |
| Isoinertial TrainingResistance training program using isoinertial devices with an emphasis on eccentric load. | Other | Arm 5: Isoinertial training + nutritional intervention |
Primary outcome
Change in fat mass
Time frame: Baseline to 9 months
Assessment of fat mass using dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis.
Change in lean body mass
Time frame: Baseline to 9 months
Assessment of lean body mass using dual-energy X-ray absorptiometry (DXA) and bioelectrical impedance analysis.
14 secondary outcomes
Change in blood glucose levels
Time frame: Baseline to 9 months
Change in triglyceride levels
Time frame: Baseline to 9 months
Change in bone mineral content
Time frame: Baseline to 9 months
Change in total cholesterol levels
Time frame: Baseline to 9 months
Change in handgrip strength
Time frame: Baseline and 9 months
Change in lower body strength (countermovement jump height)
Time frame: Baseline and 9 months
Change in sprint performance
Time frame: Baseline and 9 months
Change in endurance capacity (Yo-Yo Intermittent Recovery Test Level 1)
Time frame: Baseline and 9 months
Change in functional movement (Functional Movement Screen score)
Time frame: Baseline and 9 months
Change in joint range of motion
Time frame: Baseline and 9 months
Change in urine specific gravity
Time frame: Baseline and 9 months
Change in hydration status (urine color scale)
Time frame: Baseline and 9 months
Change in blood pressure
Time frame: Baseline and 9 months
Change in basal metabolic rate
Time frame: Baseline and 9 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Behavioral: Nutritional Intervention, Conventional Strength Training and Explosive Strength Training in people with Metabolic Health and Musculoskeletal Disorders (MSDs), run by University of Alicante at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 7 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in fat mass (time frame: Baseline to 9 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2026.