Clinical trials: Menopausal Depression
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Post Menopausal
Effects of Progressive Resistance Training Vasomotor Symptoms in Post Menopausal Women
The study will be a randomized clinical trial and will be conducted in Civil Hospital and Kalsoom Hospital Samundry. This study will be completed in time duration of 10 months after the approval of synopsis.
- Trial name
- NCT06166264
- Testing
- Progressive resistance training, Control group
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postmenopausal Depression, Estrogen
Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen
After menopause, there is a certain tendency towards depression, with the risk of developing depression being about 3 to 4 times higher than before menopause.
- Trial name
- NCT06358014
- Testing
- Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs, SSRIs
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiao Wang
Menopause, Depression
The Effect of Menopause on Sexual Life and Depression: a Case-control Study.
work completed but not yet published
- Conditions
- Menopause, Depression, Sexual Dysfunction
- Trial name
- menopause (NCT05312099)
- Testing
- Case control
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Hitit University
Menopause, Depression
Depression, Aging, Stress and Heart Health Study
Depression is a known risk factor for cardiovascular disease (CVD), and this comorbidity contributes significantly to the morbidity and mortality of women.
- Conditions
- Menopause, Depression, Heart Disease in Women, Stress
- Trial name
- DASHH (NCT05570721)
- Testing
- Trier Social Stress Test
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder, Menopausal Staging and Vasomotor Symptoms (for Females)
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI.
- Trial name
- DVS (NCT00888862)
- Testing
- Desvenlafaxine Succinate
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Menopause, Sleep Disturbance
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled, direct-to-consumer trial assessing the impact of health and wellness products on hormonal health and associated health outcomes in women with menopausal health issues
- Conditions
- Menopause, Sleep Disturbance, Anxiety, Depression
- Trial name
- NCT06749288
- Testing
- Radicle Revive Active Study Product 4.1 Usage
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Depression
Study on Allopregnanolone and Depression in Women Across the Menopause Transition
This study aims to identify how enhanced allopregnanolone activity (via pregnenolone) affects behavior and neurobiology that may underlie perimenopausal depression.
- Trial name
- SADIE-P (NCT06238700)
- Testing
- pregnenolone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Beth Israel Deaconess Medical Center
Menopause, Primary Ovarian Insufficiency (Poi)
Menopause Age and Anxiety-Depression
Menopause is defined as the permanent cessation of menstrual cycles due to ovarian follicle depletion, typically occurring after age 50, and is associated with decreased estrogen levels.
- Conditions
- Menopause, Primary Ovarian Insufficiency (Poi), Anxiety, Depression
- Trial name
- NCT07295093
- Testing
- Beck Anxıety Inventory (BAI), State-Trait Anxiety Scale (STAI) 1-2
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Menopause
The Effect of Emotional Freedom Technique on Menopausal Symptoms, Quality of Life and Depression Level
Emotional freedom technique will be applied to menopausal women. Emotional freedom technique group, sham emotional freedom technique group and control groups each consisted of 35 menopausal women.
- Trial name
- NCT06158672
- Testing
- Emotional freedom technique group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Stroke, Family Caregivers
Telephone Assessment and Skill-Building Intervention for Stroke Caregivers
The purpose of this study is to test the efficacy of the revised Telephone Assessment and Skill-Building Kit (TASK II) compared with an Information, Support, and Referral (ISR) intervention in family caregivers of stroke…
- Trial name
- TASKII (NCT01275495)
- Testing
- Telephone Assessment and Skill-Building Kit (TASK II), Information, Support, and Referral (ISR)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Indiana University
Menopause, Anxiety Disorders
Treating Climacteric Symptoms With a Complex Homeopathic Remedy
The purpose of this study is to determine whether ovaria comp. is effective in relieving climacteric symptoms.
- Conditions
- Menopause, Anxiety Disorders, Depression
- Trial name
- NCT00152776
- Testing
- ovaria comp 10 globuli 3 times per day 24 weeks
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Depressive Disorder, Major, Menopause
Estrogen and Perimenopausal Depression
During perimenopause (the time just prior to menopause), women often notice many biological, psychological, and social changes. In particular, some women experience depressive symptoms during perimenopause that are severe enough…
- Trial name
- NCT00229450
- Testing
- Estrogen
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Anxiety Disorder, Depressive Disorder
Sub-Trial of the Youth Readiness Intervention (YRI): Treatment of Control Group and Addition of Stress Biomarkers
This research is a continuation of the Youth Readiness Intervention (YRI) randomized clinical trial by adding additional pre and post intervention data collection upon treatment of the control group (N=222) with the intervention…
- Conditions
- Anxiety Disorder, Depressive Disorder, Social Problems, Stress, Psychological
- Trial name
- NCT02128568
- Testing
- Youth Readiness Intervention
- Where
- Sierra Leone
- Sponsor
- Harvard School of Public Health (HSPH)
Menopausal Depression
Tibolone and Placebo in Adjunct to Antidepressant Medication for Women With Menopausal Depression
Longitudinal epidemiological studies have shown that many women experience significant physical and psychological changes as they approach menopause and for a long time following.
- Trial name
- NCT01470092
- Testing
- Tibolone
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- The Alfred
Menopause, Depression
Impact of Hot Flashes on Sleep and Mood Disturbance
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep…
- Conditions
- Menopause, Depression, Hot Flashes
- Trial name
- NCT01116401
- Testing
- leuprolide
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Menopause
Clinical Pilates and Aerobic Exercise in Menopause
To the best of our knowledge, there is no study in the literature that examined the effects of clinical Pilates training on vasomotor symptoms, quality of life, depression, and sleep problems versus aerobic exercises in…
- Trial name
- NCT05764031
- Testing
- Clinical pilates exercise, Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Major Depressive Disorder, Vasomotor Symptoms
Desvenlafaxine Succinate (Pristiq): Postmarketing Surveillance Study Among Filipino Patients
This is a non-interventional study to review safety data on administration of desvenlafaxine succinate among Filipino patients with MDD and VMS per usual clinical practice within the first three years post commercial distribution.
- Trial name
- NCT01353963
- Testing
- desvenlafaxine succinate
- Where
- 3 sites in Philippines
- Volunteers
- 13 people
- Sponsor
- Pfizer
Depressive Disorder, Mood Disorder
Treatment of Mid-Life-Related Mood Disorders
Dehydroepiandrosterone (DHEA) is a hormone produced by the adrenal gland. As humans grow older the levels of DHEA naturally decrease.
- Trial name
- NCT00001487
- Testing
- Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Therapeutic Touch, Menopausal Symptoms
The Effects of Reiki on Menopausal Symptoms and Depression Levels
Objective: This study was conducted to determine the effects of Reiki applied to women in the postmenopausal period on menopausal symptoms and depression levels.
- Trial name
- NCT05977426
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University