Clinical trials: Marijuana Usage
Anxiety, Depression
Evaluating the Impact of Psychotherapeutic Advertising Claims on Cannabis Purchasing
In the U.S., legal cannabis is frequently advertised as an effective treatment for mental health problems such as anxiety and depression-particularly online.
- Conditions
- Anxiety, Depression, Cannabis Use
- Trial name
- NCT07216911
- Testing
- CC, PAC, WL
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Marijuana Abuse
Treatment for Adolescent Marijuana Abuse
Marijuana remains the most prevalent illicit substance used by adolescents and the number of adolescents receiving treatment for marijuana abuse more than tripled during the last decade.
- Trial name
- NCT00580671
- Testing
- MET/CBT, CM, BPT
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alcohol Misuse, Cannabis Misuse
Substance Use in Assault-Injured Young Adults
This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis.
- Trial name
- NCT07070414
- Testing
- Brief Negotiation Interview intervention (BNI) (adapted)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Psychosis, Cannabis Use
Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis
Canada reports some of the highest rates of cannabis use in our youth and young adult populations, among all the developed countries.
- Trial name
- NCT07001878
- Testing
- Metformin
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Nova Scotia Health Authority
Dual Diagnosis, Risk Youth
Virtual Reality (VR-GINSO) as an Complement to Intervention for Alcohol and Cannabis Use in Youth in Residential Care
The goal of this RCT is to evaluate the effects of a virtual reality intervention on self-efficacy regarding alcohol and cannabis use among at-risk youth in various residential mental health treatment centers who have…
- Conditions
- Dual Diagnosis, Risk Youth, Antisocial Behavior
- Trial name
- VR-GINSO (NCT07834606)
- Testing
- Virtual Reality, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad Francisco de Vitoria
Sexual Behavior, Alcohol Drinking
Adolescent Safer Sex Social Network Intervention
Social networks are thought to hold the potential for shaping behavior on the grounds that social and situational factors more strongly influence behavior than do personality variables.
- Conditions
- Sexual Behavior, Alcohol Drinking, Marijuana Smoking
- Trial name
- NCT00107562
- Testing
- Adolescent Safer Sex Social Network Intervention
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cannabis Use Disorder, Healthy
SV2A Density Cannabis Use Disorder
The main purpose of this study is to determine whether hippocampal synaptic vesicle density estimated by hippocampal [11C]APP-311/[11C]UCB-J binding in individuals diagnosed with cannabis use disorder (CUDs) improves with at…
- Trial name
- NCT05472818
- Testing
- [11C]APP311
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yale University
Women's Sexual Health
The Correlation of Women's Sexual Health and Marijuana Use
This study is attempting to determine whether there is any effect (worsening or improvement of sexual function) after marijuana consumption.
- Trial name
- NCT02865096
- Where
- United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Schizophrenia, Dual Diagnosis
Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?
In this translational research proposal, based on our formulation, we seek to confirm and expand upon data obtained in our pilot study suggesting that cannabis and the cannabinoid agonist dronabinol, given in low dose to patients…
- Conditions
- Schizophrenia, Dual Diagnosis, Psychotic Disorder, Cannabis Use Disorder
- Trial name
- NCT01964404
- Testing
- Marijuana, Dronabinol
- Where
- 2 sites in United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cannabis Use
CanCope: Digital Intervention for Coping With Cannabis Craving
The CanCope Study is a micro-randomized trial conducted to gather evidence about and compare the effectiveness of a momentary intervention to help young adults cope with cannabis cravings as they attempt to reduce their use.
- Trial name
- NCT05328362
- Testing
- CanCope
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Trustees of Dartmouth College
Cannabis Use, Psychiatric Disorder
An Electronic Intervention to Reduce Cannabis Among Young Adults in Psychiatric Care
Cannabis use disorders are common among young adults in psychiatric treatment. Unfortunately, cannabis use can result in deleterious consequences for those in treatment, including developing more severe psychopathology and poorer…
- Trial name
- NCT04174963
- Testing
- eToke + TPsy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Cannabis Use Disorder
Trial of Tirzepatide for the Treatment of Cannabis Use Disorder
The purpose of this randomized, double-blind, placebo-controlled, multi-site clinical trial is to evaluate the safety and efficacy of tirzepatide in a sample of 100 patients diagnosed with moderate or severe CUD by DSM-5 criteria.
- Trial name
- NCT07468552
- Testing
- Tirzepatide
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Use Disorder, Moderate
Cortical Excitability and Role of rTMS in Cannabis Use Disorder
Repetitive transcranial magnetic stimulation (rTMS) and cortical excitability have a role in cannabis use disorder
- Trial name
- NCT04106336
- Testing
- rTMS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Opioid Use Disorder
Reducing Pain and Opioid Use With CBD
This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to reduce opioid use, anxiety, and pain and improve sleep and…
- Trial name
- NCT05299944
- Testing
- Cannabidiol
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of Colorado, Denver
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Posttraumatic Stress Disorder, Cannabis Use Disorder
Mitigating PTSD-CUD After Sexual Assault
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD).
- Trial name
- RISE-C (NCT05989841)
- Testing
- RISE Guide, Relaxation Control
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Nevada, Las Vegas
Chronic Obstructive Pulmonary Disease
Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)
The main hypothesis is that persons that smoke or smoked tobacco and marihuana have worsen lung function as compared with persons that only smoke or smoked tobacco.
- Trial name
- NCT01096303
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Health Risk Behaviors, Risk Reduction Behavior
Enhancing Quality in Protective Strategies
The most successful young adult alcohol or marijuana interventions involve the provision of accurate, nonjudgmental personalized feedback, but notably the inclusion and effectiveness of protective behavioral strategies (PBS)…
- Trial name
- EQUIP (NCT04978129)
- Testing
- Online and Text Messaging Intervention
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority