Clinical trials: Magnesium Sulfate
Patients Undergoing Lumbar Fixation
Effect of Intraoperative Magnesium Sulphate on the Occurrence of Postoperative Delirium
Anaesthesia-related complications and mortality have been significantly reduced in the last years.(1) Nevertheless, anaesthesia-related side effects, such as post-operative delirium and sleep disturbances should not be…
- Trial name
- NCT05632159
- Testing
- Mg sulphate, conventional anaesthesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Opioids, Clinical Trial
The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon
Recently, a lot of side effects have been identified from the perioperative use of opioids. To remedy this, anesthesia research has recently focused on providing safe general anesthesia without opioids in a new concept or…
- Conditions
- Opioids, Clinical Trial, Anesthesia, Gynecology
- Trial name
- OFA-AFRO (NCT04737473)
- Testing
- Opiod Free Anesthesia
- Where
- Cameroon
- Volunteers
- 36 people
- Sponsor
- University of Yaounde 1
Preeclampsia and Eclampsia
Springfusor for Administration of Magnesium Sulphate in Preeclampsia and Eclampsia
Magnesium Sulphate is the drug of choice for prevention and treatment of seizures in preeclampsia and eclampsia. It is administered parenterally by intravenous (IV) and or intramuscular (IM) routes.
- Trial name
- NCT03549767
- Testing
- Springfusor, Standard of care
- Where
- Uganda
- Volunteers
- 241 people
- Sponsor
- Makerere University
Duloxetine, Magnesium Sulphate
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.
- Conditions
- Duloxetine, Magnesium Sulphate, Post-mastectomy Pain Syndrome
- Trial name
- NCT06087211
- Testing
- Magnesium sulphate and Duloxetine, Duloxetine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Magnesium Sulfate, Thromboelastometry
Magnesium Sulfate and Postoperative Hypercoagulability in Laparoscopic Gynecological Surgeries
This will be a prospective randomized, double-blind study, aiming at investigating the effects of magnesium sulfate on postoperative hypercoagulability in patients undergoing laparoscopic gynecological surgeries under general…
- Trial name
- NCT06717490
- Testing
- Magnesium sulphate
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marianna Mavromati
Preterm Premature Rupture of Membranes
Magnesium Sulfate Versus Placebo for Tocolysis in PPROM
Study compares the outcomes of women between 26 and 32 wks gestation with rupture of membranes. Women randomized to receive tocolysis with magnesium sulfate x 48 hrs or placebo of saline IV x 48 hrs.
- Trial name
- NCT00463736
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Regional Obstetrical Consultants
Acute Headache, Migraine
High- vs Standard-Dose Intravenous Magnesium for Acute Headache
Headache is one of the most common reasons for consultation in emergency departments and represents a significant cause of disability, particularly in patients with migraine and other primary headache disorders.
- Conditions
- Acute Headache, Migraine, Tension-type Headache, Cluster Headache
- Trial name
- MAGHEAD (NCT07779486)
- Testing
- Magnesium Sulfate 2 grams, Magnesium Sulfate 4 G, Paracetamol 1 g
- Where
- Tunisia
- Volunteers
- 300 people
- Sponsor
- University of Monastir
Local Anesthesia
Effect of Lidocaine With Magnesium Sulfate on the Success of the Inferior Alveolar Nerve Block
68 healthy patients pulpitis and requiring root canal therapy are selected. . Sampling was done in a simple and non-experimental way from a dental clinic in Isfahan, and then the samples were randomly assigned to one of the two…
- Trial name
- NCT03262857
- Testing
- use of magnesium sulfate with lidocaine in inferior alveolar nerve block
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Spine Surgery
Effect of TIVA With Magnesium Sulfate on IONM in Patients Undergoing Spine Surgery
Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression.
- Trial name
- NCT04716439
- Testing
- Spine Surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Khalid University Hospital
Arrhythmias
Antiarrhythmic and Cardioprotective Effects of Atorvastatin Versus Magnesium Sulfate in Cardiac Valve Replacement Surgery
This study aims to compare the antiarrhythmic and cardioprotective effects of Atorvastatin versus Magnesium Sulfate after Cardiac valve Replacement Surgery
- Trial name
- NCT03289429
- Testing
- Atorvastatin, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Arthropathy of Knee, Magnesium Sulfate
Magnesium Sulfate and Neuroendocrine Hormone
Total knee arthroplasty is a procedure that relieves pain in patients with severe symptomatic osteoarthritis, but it can be associated with postoperative pain, which hinders recovery.
- Conditions
- Arthropathy of Knee, Magnesium Sulfate, Cortisol, Dehydroepiandrosterone
- Trial name
- NCT04514731
- Testing
- Magnesium sulfate, Isotonic Saline
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Abdominal Aortic Surgery
The Effect of Intraperitoneal Injection of Magnesium Sulphate Versus Dexmedetomidine as an Adjuvant to Bupivacaine on Postoperative Analgesia in Patients Undergoing Abdominal Aortic Surgery
optimal management of postoperative pain is essentiel for better outcome in abdominal aortic surgery.the study aim to compare between analgesic effect of magnesium sulphate versus dexmedetomidine as an adjuvant to bupivacaine…
- Trial name
- NCT05577260
- Testing
- magnesuim sulphate, Dexmedetomidine, isobaric bupivacaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Preeclampsia/Eclampsia
Low Dose Magnesium Sulphate Versus Standard Pritchard Regimen In Management Of Severe Preeclampsia/Eclampsia
Background - Preeclampsia/eclampsia, a pregnancy specific multi-systemic disease, is associated with considerable maternal and perinatal morbidity and mortality.
- Trial name
- NCT04501289
- Testing
- Low dose magnesium sulphate, Pritchard regimen
- Where
- Nigeria
- Volunteers
- 114 people
- Sponsor
- Adebayo Joshua Adeniyi
Muscle Relaxation
MgSO4 Combined With Rocuronium Priming
Priming with either rocuronium or MgSO4 is known to accelerate the effect of rocuronium on muscle relaxation. The purpose of this study is to define the effect of MgSO4 on the rocuronium-priming.
- Trial name
- NCT01389791
- Testing
- magnesium sulfate, priming, magnesium sulfate and priming
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Pain
The Analgesic Efficacy of Magnesium and Ketorolac in Ultrasound Supraclavicular Block
Despite many regional anesthetic techniques have been described for anesthesia of the brachial plexus which is responsible for the sensory and motor innervation of entire upper limb, still, supraclavicular block (SCB) is the…
- Trial name
- NCT04554862
- Testing
- Magnesium sulfate, Ketorolac Tromethamine, supraclavicular block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital
Analgesia
Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery
Regional analgesia is considered the cornerstone for postoperative analgesia in paediatric patients. One of the most common birth defects which require surgical intervention early in life is the cleft lip.
- Trial name
- NCT05624151
- Testing
- Dexmedetomidine +Bupivacaine, Magnesium Sulfate + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Colorectal Cancer
Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
The purpose of this study is to investigate Suprep bowel preparation, with and without the anti-gas medication simethicone, in terms of efficacy and patient tolerability in the preparation of patients undergoing routine…
- Trial name
- NCT02523911
- Testing
- Simethicone, sodium sulfate/potassium sulfate/magnesium sulfate solution
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MercyOne Des Moines Medical Center
Wound Heal
Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model
An experimental study examining wound healing in 5 different groups on 30 rats.
- Trial name
- NCT04886882
- Testing
- Experimental drug 1, Experimental drug 2, Centella asiatica
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Bronchiolitis, Magnesium, Abnormal Blood Level
Efficacy of Magnesium Sulfate in the Treatment of Bronchiolitis
In this study, investigators will compare the efficacy and safety of intravenous (IV) Magnesium sulfate in decreasing bronchiolitis clinical severity score and the duration of hospitalization in admitted patients, as compared to…
- Trial name
- NCT02145520
- Testing
- Magnesium Sulfate
- Where
- Qatar
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation