Clinical trials: Lung Function
Healthy Volunteers
Healthy Lung Study- Development of 3T MRI Hardware and Software for 3He Gas Imaging of the Lung: Healthy Volunteer Development Study
Healthy volunteers aged 18-75 will undergo hyperpolarized 3-Helium MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
- Trial name
- NCT03169673
- Testing
- Hyperpolarized Helium 3 Magnetic Resonance Imaging
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Cystic Fibrosis
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function
Malnutrition is a significant problem in children and adults with Cystic fibrosis (CF). An impaired intestinal digestion and absorption capacity is one of the main factors responsible for the malnutrition in CF.
- Trial name
- NCT01494909
- Testing
- Ensure plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Fear Anxiety, Pulmonary
Preparation Methods on PFT Performance
Background: Successful spirometry in children depends on adequate cooperation and correct performance of respiratory maneuvers. Although several preparation strategies have been proposed, evidence comparing their effects on both…
- Conditions
- Fear Anxiety, Pulmonary, Performance Assessment
- Trial name
- NCT07713225
- Testing
- Verbal Instruction with Demonstration, Animation-Assisted Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Pregnancy Related
Balance, Pulmonary Function, and Low Back Pain in Pregnant and Non-pregnant Women
The aims of this study were to investigate balance and pulmonary functions in pregnant and non-pregnant women and to determine their relationship with LBP.
- Trial name
- NCT03467321
- Testing
- Physical characteristic assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seyda TOPRAK CELENAY
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Lung Diseases, Interstitial
Assessment of Neuropsychiatric Function in Patients With Interstitial Lung Disease
Research on the impact of lung diseases on neuropsychological functioning has revealed impaired cognitive processing in patients with a variety of pulmonary disorders.
- Trial name
- NCT05719233
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Iron-deficiency, Ventricular Function
Iron Status and Cardiopulmonary Physiology
This study involved human volunteers undertaking a high-altitude expedition. It assessed changes in physiological parameters of relevance to high-altitude cardiopulmonary physiology.
- Conditions
- Iron-deficiency, Ventricular Function, Pulmonary Vascular Resistance Abnormality, Altitude Hypoxia
- Trial name
- NCT03707249
- Testing
- Ferric Carboxymaltose Injectable Product, Normal Saline 0.9% Infusion Solution Bag
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Royal Centre for Defence Medicine
Stable COPD Patients
Study on the Mechanism of Yifei Moxibustion Improving Immune Function in COPD Based on Plasma Exosome miRNAs
This study adopted a randomized controlled design, enrolling 90 patients and 30 healthy volunteers. The patients were randomly divided into the Yifei Moxibustion group, the conventional Western medicine treatment group, and the…
- Trial name
- NCT07131020
- Testing
- Yifei moxibustion, Conventional Western medicine treatment, TCM syndrome differentiation treatment
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
COPD, Obstructive Ventilation Disorder
Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the…
- Conditions
- COPD, Obstructive Ventilation Disorder, Pulmonary Emphysema
- Trial name
- NCT02827721
- Testing
- impulse oscillometry, multiple breath washout test, body plethysmography
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
COPD
Comparing Pressure Based and Dilution Based Total Lung Capacity Measurements in COPD Patients for Lung Function Diagnostics
Total Lung Capacity (TLC) of the lungs can be determined using a pressure based method (i.e. by body plethysmography) or it can be determined using a dilution based method (i.e.
- Trial name
- NCT04531293
- Testing
- Respiratory Analysis System
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- ndd Medizintechnik AG
Pulmonary Function, Aerobic Performance
Pulmonary Function and Trunk Muscle Performance in Wrestlers
This study aims to investigate the relationships among pulmonary function, aerobic performance, anaerobic performance, and isokinetic trunk muscle performance in professional male wrestlers.
- Conditions
- Pulmonary Function, Aerobic Performance, Anaerobic Performance, Isokinetic Test
- Trial name
- NCT07792174
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Respiratory Function, Vocal Performance
Combined SOVT and Respiratory Exercises: Effects on MPT and Respiratory Function
This study aims to investigate the effects of combined SOVT and breathing exercises, administered twice weekly for six weeks to conservatory students, through a randomized controlled trial.
- Conditions
- Respiratory Function, Vocal Performance, Voice
- Trial name
- NCT07677501
- Testing
- combined soft and breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Metabolomics, Omega 6
The Research of Metabolomics on COPD
Targeted metabolomics research was conducted on patients with chronic obstructive pulmonary disease (COPD). The correlation analyst between inflammation-related metabolites and lung function was analyzed by explored the metabolic…
- Conditions
- Metabolomics, Omega 6, Omega 3, COPD
- Trial name
- COPD (NCT04042519)
- Testing
- Lung function test was performed on the subjects with Jaeger lung function instrument of Germany., Agilent 1290 Infinity LC system (UHPLC, Santa Clara CA) was used for Targeted metabolite detection., Routine blood test
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Stroke Patients
Relationship Between Respiratory Muscle Strength, Balance, Trunk Control, Functional Capacity in Stroke Patients
The purpose of this study; To determine the relationship between respiratory muscle strength, balance, trunk control, functional capacity and motor functions in stroke patients and compare them with healthy individuals.
- Trial name
- NCT06259877
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
COVID-19
COVID Booster in Pregnancy and Lactation
This is a prospective longitudinal cohort study to evaluate the impact of COVID-19 vaccination and booster on maternal and infant immunity against COVID-19 variants over time.
- Trial name
- NCT05543993
- Testing
- Bivalent COVID-19 Booster
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cystic Fibrosis
Functional Analysis by Dynamic Imaging of the Respiratory Epithelium in Infants With Cystic Fibrosis
Cystic fibrosis (CF) is characterized by airway inflammation and infection leading to progressive destruction of lungs. One of the most important abnormalities in CF is an abnormal processing of the mutated CFTR protein through…
- Trial name
- NCT01605565
- Testing
- A nasal brushing
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Aging
Effects of Exergames on Muscle and Lung Function in Elderly
The goal of this study is to examine the effects of 8-weeks exergames program on pulmonary function, muscle strength and cognitive function in elderly.
- Trial name
- NCT06921057
- Testing
- exergame
- Where
- Taiwan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London