Clinical trials: Lumbar Radiculopathy, open to volunteers
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Lumbar Disc Herniation, Chronic Low Back Pain
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
This prospective, randomized, single-blinded, controlled clinical trial aims to compare the effectiveness of high-intensity laser therapy and fluoroscopy-guided transforaminal epidural steroid injection in patients with chronic…
- Conditions
- Lumbar Disc Herniation, Chronic Low Back Pain, Radicular Pain, Lumbar Radiculopathy
- Trial name
- NCT07688915
- Testing
- High-Intensity Laser Therapy, Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Radiculopathy
Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties.
- Trial name
- NCT07726823
- Testing
- Mulligan Bent Leg Raise (MBLR), Spinal Mobilization With Leg Movement (SMWLM)
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Lumbar Radiculopathy, Discogenic Lumbosacral Radiculopathy
Effect of Trans-spinal Electromagnetic Neuromodulation in Treatment of Patients With Discogenic Lumbosacral Radiculopathy
Purposes of the study To investigate the effect of adding Trans-spinal Electromagnetic Neuromodulation to conventional physical therapy in patients with Discogenic Lumbosacral Radiculopathy
- Trial name
- NCT07743424
- Testing
- Trans-spinal Electromagnetic Neuromodulation, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yara Aboelazm Abd Elaziz Mohamed
Lumbar Radiculopathy
Femoral Stretch Test in L2-L4 Lumbar Radiculopathy
This prospective observational study aims to evaluate the sensitivity of the femoral stretch test in patients with unilateral, single-root L2, L3, or L4 nerve root compression and to determine whether test positivity differs…
- Trial name
- NCT07799142
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Lumbar Radiculopathy
The Aim of Study is to Identify the Predictive Factors for the Success of Transforaminal Epidural Injection in Treatment of Patients with Lumbosacral Radiculopathy
the aim of the study is to identify predictive factors for the success of transforaminal epidural injection in the treatment of patients with lumbosacral radiculopathy
- Trial name
- NCT06795542
- Testing
- lumbosacral transforaminal epidural injection at the level of L4-5, L5-S1, or S1 neural foramina
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amr Mohamed Sedik
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Lumbar Disc Herniation With Radiculopathy, Sciatica
FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation
The FINDISC trial studies whether common back operation, microdiscectomy, is effective and safe for treating sciatica caused by a lumbar disc herniation.
- Trial name
- FINDISC-Pain (NCT07418944)
- Testing
- Microdiscectomy
- Where
- Finland
- Volunteers
- 122 people
- Sponsor
- Helsinki University Central Hospital
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Lumbar Radiculopathy, Chronic Pain
Effectiveness and Safety of Pharmacopuncture Therapy for Chronic Lumbar Radiculopathy: A Multicenter, Pragmatic, Randomized, Comparative Clinical Trial
A pragmatic clinical study to compare the effectiveness of pharmacopuncture and physical therapy strategies in patients with chronic lumbar radiculopathy
- Trial name
- NCT07832318
- Testing
- Pharmacopuncture, Physical Therapy
- Where
- 4 sites in South Korea
- Volunteers
- 92 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Sciatica Acute
Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department.
- Trial name
- TGSNB vs SoC (NCT07397117)
- Testing
- nerve block with ropivacaine, Standard medical treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Lumbosacral Transitional Vertebrae, Thoracolumbar Transitional Vertebra
How Reliable Are Routine Radiological Imaging Methods in Diagnosing Lumbosacral Transitional Vertebrae and Identifying the Pathological Disc Level?
The aim of this study is to evaluate how accurately transitional vertebrae can be identified using routinely employed clinical imaging methods, including thoracolumbar direct radiography and lumbar MRI with axial and sagittal…
- Conditions
- Lumbosacral Transitional Vertebrae, Thoracolumbar Transitional Vertebra, Vertebral Level Misidentification, Lumbar Radiculopathy
- Trial name
- NCT07256366
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Marmara University
Lumbar Disk Herniation, Lumbar Spinal Stenosis
Screening and Prospective Cohort Study of Risk Factors for Enhanced Recovery After Spinal Fusion Surgery in Advanced Age Patient
To determine the high risk factors affecting accelerated recovery after spinal fusion surgery in advanced age patient.
- Conditions
- Lumbar Disk Herniation, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Cervical Spondylotic Myelopathy
- Trial name
- NCT06591442
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lumbosacral Radiculopathy
Clinical Outcomes of Prone and Supine Lumbar Traction Matched to Mechanical Bias in Flexion and Extension Subgroups With Lumbosacral Radiculopathy
Aim of the study is to identify specific patient subgroups that respond optimally to prone or supine traction based on mechanical diagnosis.
- Trial name
- NCT07786402
- Testing
- group A, Group B, Group C
- Volunteers
- 28 people
- Sponsor
- Al-Ahliyya Amman University
Dorsal Root Ganglion, Pulsed Radiofrequency
The Effect of Sensory Stimulation Threshold on the Efficacy of Pulsed Radiofrequency Applied to the Dorsal Root Ganglion in Patients with Chronic Lumbar Radicular Pain
Lomber dorsal root ganglion pRF is an interventional treatment options in the treatment of lumbar radicular pain. The goal of this study is to investigate the effect of sensory threshold outcomes on pain severity during dorsal…
- Conditions
- Dorsal Root Ganglion, Pulsed Radiofrequency, Chronic Pain, Lumbar Radiculopathy
- Trial name
- NCT06756893
- Testing
- Dorsal Root Ganglion Pulsed Radiofrequency
- Volunteers
- 150 people
- Sponsor
- Ankara University
Lumbar Radiculopathy
Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica
The goal of this clinical trial is to evaluate the effect of Transfer of Energy Capacitive and Resistive (TECAR) on pain, functional disability and electrophysiological parameters in adults with chronic discogenic sciatica .
- Trial name
- NCT07841405
- Testing
- Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Radiculopathy Lumbar
Clinical and MRI Factors Associated With Procedural Difficulty in Lumbar TFESI
The technical difficulty of transforaminal epidural steroid injection (TFESI) may be influenced by patient-related characteristics, the target spinal level, a history of lumbar surgery, the presence of spinal instrumentation, and…
- Trial name
- NCT07870720
- Volunteers
- 190 people
- Sponsor
- Selcuk University