Lumbar RadiculopathyNCT07726823
Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy
A study testing Mulligan Bent Leg Raise (MBLR) and Spinal Mobilization With Leg Movement (SMWLM) in people with Lumbar Radiculopathy, run by Riphah International University at 1 site in Pakistan.
Trial summary
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties. This condition significantly disrupts daily activities and overall quality of life. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Lumbar Radiculopathy
- What is being tested?
- Mulligan Bent Leg Raise (MBLR) and Spinal Mobilization With Leg Movement (SMWLM)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 sitePakistan
- Study dates
- 20 Jun 2026to 20 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 20 to 40 years (26)
- Diagnosed patient with Unilateral Lumbar Radiculopathy secondary to L4/L5 and L5/S1 lumbar posterolateral disc buldge confirmed on MRI (12)
- Posterolateral Lumbar Radiculopathy
Who cannot join
- • Presence of red flags (e.g., cauda equina syndrome, severe neurological deficits).
- Previous spinal surgery within 1 year.
- Severe osteoporosis or vertebral fractures.
- Pregnant women.
- Systemic inflammatory or autoimmune diseases.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Femwell Physiocare Woman Rehab clinic
Lahore, Punjab Province, 54000
Arooj Fatima, MS-OMPT, 03270056769, draroohfahim@gmail.com
About this study
Official title: Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement on Pain, Neural Mobility, Balance and Functional Disability in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties. This condition significantly disrupts daily activities and overall quality of life. While medication and exercise are common treatments, manual therapy techniques are gaining recognition for their non-invasive and effective outcomes in relieving symptoms and improving patient function.
Read the detailed description
This randomized clinical trial will be conducted in Physiotherapy outpatient department of Jinnah Hospital Lahore. It will include 52 participants, aged 20 to 40 years, meeting clinical criteria for lumbar radiculopathy. Participants will be selected from an outpatient physiotherapy department and assigned randomly into two equal groups. Group A will receive the MBLR technique, while Group B will undergo the SMWLM technique. Both interventions will be applied three times a week for four weeks under standardized protocols. Key outcome measures include pain intensity assessed using the Numeric Pain Rating Scale (NPRS), neural mobility evaluated through the Straight Leg Raise (SLR) and Slump Test, and functional status measured using the Oswestry Disability Index (ODI), Timed Up and Go (TUG) test, and 5 Repetition Sit-to-Stand test for postural balance. Assessments will be conducted at baseline, after 2 weeks, at 4 weeks post-intervention, and at 8-week follow-up. Data analysis will be done by SPSS version 25. To ensure objectivity, all assessments will be conducted while keeping the patient unaware of their group assignment.
- Conditions
- Lumbar Radiculopathy
- Being tested
- Mulligan Bent Leg Raise (MBLR), Spinal Mobilization With Leg Movement (SMWLM)
- Keywords
- Neural Mobilization, Mulligan Technique, Manual Therapy
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mulligan Bent Leg Raise (MBLR)Other
Patient Position - Supine at edge of plinth
- Affected hip and knee flexed to 90°
- Hand of affected side under head and neck Therapist Position - Stands in walk stance, lateral to affected limb Therapist Hand Placement - Inner shoulder under popliteal fossa
- Both hands grasp lower thigh Mobilization Procedure - Apply longitudinal traction along femur
- Flex hip toward same side shoulder until first resistance
- Patient performs isometric hold (5 sec)
- On relaxation, increase hip flexion if pain free
- Hold new position ~20 sec
- Repeat 3 times if tolerated Precautions - Maintain knee flexion
- No need to stabilize opposite leg
Spinal Mobilization With Leg Movement (SMWLM)Other
Patient Position - Side-lying on unaffected side near edge
- Affected leg on top, supported by assistant
- Hip abducted ~10°, extended; knee flexed ~45° Therapist Position - Primary therapist behind pelvis
- Assistant supports upper leg during movement Therapist Hand Placement - Supported thumb on spinous process of affected vertebra
- Gentle transverse pressure maintained throughout movement Mobilization Procedure - Assistant helps patient actively lift leg (SLR)
- Movement within pain free range
- If symptoms appear, hold for ~3 sec then return
- Start with 3 reps; increase to 6 with light overpressure as tolerated Precautions - Stay within non painful range
- Maintain steady, controlled transverse pressure
- Avoid excessive force, especially early on
| Study group | Role | What they receive |
|---|---|---|
| Mulligan Bent Leg Raise (MBLR) | Experimental | The Mulligan Bent Leg Raise (BLR) technique is a specialized physical therapy mobilization method used to relieve low back pain, reduce sciatica, and improve hamstring flexibility. It involves applying gentle, pain-free traction while moving the leg through progressively greater ranges of hip flexion. Receives: Other: Mulligan Bent Leg Raise (MBLR) |
| Spinal Mobilization with Leg Movement (SMWLM) | Active comparator | Spinal Mobilization with Leg Movement (SMWLM) is an advanced manual therapy technique developed as part of the Mulligan Concept. It integrates manual joint mobilization with neurodynamic principles to treat lower back and radiating leg pain, most notably lumbar radiculopathy (sciatica) Receives: Other: Spinal Mobilization With Leg Movement (SMWLM) |
What is being measured
The primary outcome is the main question the study is designed to answer.
NPRS for pain
Pain intensity will be evaluated using the Numeric Pain Rating Scale, which ranges from 0 indicating "no pain" to 10 representing the "worst possible pain." It has shown excellent test-retest reliability, with intraclass correlation coefficients (ICC) ranging between 0.95 and 0.98 in individuals with musculoskeletal conditions
Measured: upto 4 weeks
SLR and Slump test for neural mobility
To assess neural mobility, the Straight Leg Raise and Slump Tests will be employed. These are well-established clinical tools for identifying lumbar nerve root irritation. The SLR test demonstrates strong diagnostic accuracy (~81%) and excellent inter-rater reliability with kappa values above 0.90 and aprox 0.71 for slump test
Measured: Upto 4 weeks
Oswestry Disability Index test for functional outcome
The ODI will be used to determine the level of functional disability associated with lower back pain. It includes 10 items that assess various aspects of daily activity. The tool has proven to be highly reliable (Cronbach's alpha = 0.87) and valid across different patient populations with lumbar spine conditions
Measured: Upto 4 weeks
Time up and go (TUG) test for functional outcome
Balance and functional mobility will be measured using the TUG test, which involves timing a patient as they rise from a chair, walk three meters, turn, return, and sit down. This test is highly reliable (ICC = 0.82 to 0.99) and shows good concurrent validity in both spinal and geriatric populations (34). The cutoff value for balance and functional mobility TUG test is 7.2 sec
Measured: Upto 4 weeks
Five repetition sit to stand test
The 5 Rep Sit-to-Stand Test will be used to assess lower limb strength and functional performance. The patient gets to their maximum standing position and then sits back down five times as fast as they can without the use of their hands or arms. It has demonstrated excellent reliability (ICC > 0.90) and shows strong correlation with functional ability (36). The cutoff value is > 10 sec for 5 rep sitting to standing and standing to sitting transition
Measured: upto 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2026
- Study start20 Jun 2026
- Primary completion20 Aug 2026 (estimated)
- Study completion20 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (10)Papers the sponsor has linked to this study.
- Other trials for Lumbar RadiculopathyStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Amna Zia, PhD, Principal investigator, King Edward Medical UniversityMuniba Tahir, Principal investigator, Riphah International University, Lahore Campus
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07726823
- Sponsor's protocol ID
- REC/RCR&AHS/25/0132 Muniba
- Status last verified
- Jul 2026
- First submitted
- 21 Jul 2026
- Last updated
- 24 Jul 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Senol D, Erdem C, Canbolat M, Toy S, Karatas T, Baykara RA, Ozbag D, Akyurek G. Comparison of the effects of conventional physiotherapy and proprioception exercises on pain and ankle proprioception in patients with lumbar radiculopathy. J Back Musculoskelet Rehabil. 2022;35(2):421-428. doi: 10.3233/BMR-200361.
PubMed 34308899Ashraf B, Ahmad S, Ashraf K, Kanwal S, Ashraf S, Khan N, et al. Effectiveness of spinal mobilization with leg movement versus McKenzie back extension exercises in lumbar radiculopathy. 2021;15(5):1436-40.
Fatima A, Mehmood Z, Ahmad SJJoIIMC. Effects of Mulligan Traction Straight Leg Raise Versus Passive Straight Leg Raise in Lumbar Radiculopathy Patients. 2022;17(2):86-90.
Singh V, Malik MJRJoN. Lumbar radiculopathy managed with spinal mobilization with leg movement: A case study. 2021;20(2):246-9.
Naidu SP, Srikantaiah S, Boyle RJIJoPT, Research. Immediate Effect of Mulligan's Spinal Mobilization with Limb Movements on Straight Leg Raise Test in Patients with Lumbar Radiculopathy: A Randomized Controlled Trial. 2023;5(1):66-72.
Singh V, Malik MJAiR. Effect of manual therapy on pain, disability and neural mobility in patients of lumbar prolapsed intervertebral disc: a randomized controlled trial. 2022;36(3):11-8.
Yasmeen S, Ahmad Z, Ishtiaq NJJRCoRS. The comparative effects of Butler's neural tissue mobilization and Mulligan's Bent leg raise in patients with chronic lumbar radiculopathy. 2022;10(02).
Lin LH, Lin TY, Chang KV, Wu WT, Ozcakar L. Neural Mobilization for Reducing Pain and Disability in Patients with Lumbar Radiculopathy: A Systematic Review and Meta-Analysis. Life (Basel). 2023 Nov 26;13(12):2255. doi: 10.3390/life13122255.
PubMed 38137856Hussein H, Atteya M, Ansari A, Kamel E. A Systematic Review and Meta-Analysis of the Effectiveness of Mulligan Mobilization with Movement on Pain, Range of Motion, Function, and Flexibility in Patients with Sciatica. NeuroRehabilitation. 2025 Mar;56(2):83-96. doi: 10.1177/10538135241301693. Epub 2024 Dec 18.
PubMed 40260717George SZ, Fritz JM, Silfies SP, Schneider MJ, Beneciuk JM, Lentz TA, Gilliam JR, Hendren S, Norman KS. Interventions for the Management of Acute and Chronic Low Back Pain: Revision 2021. J Orthop Sports Phys Ther. 2021 Nov;51(11):CPG1-CPG60. doi: 10.2519/jospt.2021.0304.
PubMed 34719942
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement on Pain, Neural Mobility, Balance and Functional Disability in Lumbar Radiculopathy
- ClinicalTrials.gov ID
- NCT07726823
- Acronym / sponsor ID
- REC/RCR&AHS/25/0132 Muniba
- Conditions
- Lumbar Radiculopathy
- Keywords
- Neural Mobilization, Mulligan Technique, Manual Therapy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 20 Jun 2026 (actual)
- Primary completion
- 20 Aug 2026 (estimated)
- Study completion
- 20 Sep 2026 (estimated)
- First posted
- 24 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties. This condition significantly disrupts daily activities and overall quality of life. While medication and exercise are common treatments, manual therapy techniques are gaining recognition for their non-invasive and effective outcomes in relieving symptoms and improving patient function.
Detailed description
This randomized clinical trial will be conducted in Physiotherapy outpatient department of Jinnah Hospital Lahore. It will include 52 participants, aged 20 to 40 years, meeting clinical criteria for lumbar radiculopathy. Participants will be selected from an outpatient physiotherapy department and assigned randomly into two equal groups. Group A will receive the MBLR technique, while Group B will undergo the SMWLM technique. Both interventions will be applied three times a week for four weeks under standardized protocols. Key outcome measures include pain intensity assessed using the Numeric Pain Rating Scale (NPRS), neural mobility evaluated through the Straight Leg Raise (SLR) and Slump Test, and functional status measured using the Oswestry Disability Index (ODI), Timed Up and Go (TUG) test, and 5 Repetition Sit-to-Stand test for postural balance. Assessments will be conducted at baseline, after 2 weeks, at 4 weeks post-intervention, and at 8-week follow-up. Data analysis will be done by SPSS version 25. To ensure objectivity, all assessments will be conducted while keeping the patient unaware of their group assignment.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Mulligan Bent Leg Raise (MBLR) | Experimental | Other: Mulligan Bent Leg Raise (MBLR)The Mulligan Bent Leg Raise (BLR) technique is a specialized physical therapy mobilization method used to relieve low back pain, reduce sciatica, and improve hamstring flexibility. It involves applying gentle, pain-free traction while moving the leg through progressively greater ranges of hip flexion. |
| Spinal Mobilization with Leg Movement (SMWLM) | Active comparator | Other: Spinal Mobilization With Leg Movement (SMWLM)Spinal Mobilization with Leg Movement (SMWLM) is an advanced manual therapy technique developed as part of the Mulligan Concept. It integrates manual joint mobilization with neurodynamic principles to treat lower back and radiating leg pain, most notably lumbar radiculopathy (sciatica) |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Age 20 to 40 years (26)
- Diagnosed patient with Unilateral Lumbar Radiculopathy secondary to L4/L5 and L5/S1 lumbar posterolateral disc buldge confirmed on MRI (12)
- Posterolateral Lumbar Radiculopathy
Key exclusion criteria (5 listed)
- • Presence of red flags (e.g., cauda equina syndrome, severe neurological deficits).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mulligan Bent Leg Raise (MBLR)Patient Position - Supine at edge of plinth * Affected hip and knee flexed to 90° * Hand of affected side under head and neck Therapist Position - Stands in walk stance, lateral to affected limb Therapist Hand Placement - Inner shoulder under popliteal fossa * Both hands grasp lower thigh Mobilization Procedure - Apply longitudinal traction along femur * Flex hip toward same side shoulder until first resistance * Patient performs isometric hold (5 sec) * On relaxation, increase hip flexion if pain free * Hold new position ~20 sec * Repeat 3 times if tolerated Precautions - Maintain knee flexion * No need to stabilize opposite leg | Other | Mulligan Bent Leg Raise (MBLR) |
| Spinal Mobilization With Leg Movement (SMWLM)Patient Position - Side-lying on unaffected side near edge * Affected leg on top, supported by assistant * Hip abducted ~10°, extended; knee flexed ~45° Therapist Position - Primary therapist behind pelvis * Assistant supports upper leg during movement Therapist Hand Placement - Supported thumb on spinous process of affected vertebra * Gentle transverse pressure maintained throughout movement Mobilization Procedure - Assistant helps patient actively lift leg (SLR) * Movement within pain free range * If symptoms appear, hold for ~3 sec then return * Start with 3 reps; increase to 6 with light overpressure as tolerated Precautions - Stay within non painful range * Maintain steady, controlled transverse pressure * Avoid excessive force, especially early on | Other | Spinal Mobilization with Leg Movement (SMWLM) |
Primary outcome
NPRS for pain
Time frame: upto 4 weeks
Pain intensity will be evaluated using the Numeric Pain Rating Scale, which ranges from 0 indicating "no pain" to 10 representing the "worst possible pain." It has shown excellent test-retest reliability, with intraclass correlation coefficients (ICC) ranging between 0.95 and 0.98 in individuals with musculoskeletal conditions
SLR and Slump test for neural mobility
Time frame: Upto 4 weeks
To assess neural mobility, the Straight Leg Raise and Slump Tests will be employed. These are well-established clinical tools for identifying lumbar nerve root irritation. The SLR test demonstrates strong diagnostic accuracy (~81%) and excellent inter-rater reliability with kappa values above 0.90 and aprox 0.71 for slump test
Oswestry Disability Index test for functional outcome
Time frame: Upto 4 weeks
The ODI will be used to determine the level of functional disability associated with lower back pain. It includes 10 items that assess various aspects of daily activity. The tool has proven to be highly reliable (Cronbach's alpha = 0.87) and valid across different patient populations with lumbar spine conditions
Time up and go (TUG) test for functional outcome
Time frame: Upto 4 weeks
Balance and functional mobility will be measured using the TUG test, which involves timing a patient as they rise from a chair, walk three meters, turn, return, and sit down. This test is highly reliable (ICC = 0.82 to 0.99) and shows good concurrent validity in both spinal and geriatric populations (34). The cutoff value for balance and functional mobility TUG test is 7.2 sec
Five repetition sit to stand test
Time frame: upto 4 weeks
The 5 Rep Sit-to-Stand Test will be used to assess lower limb strength and functional performance. The patient gets to their maximum standing position and then sits back down five times as fast as they can without the use of their hands or arms. It has demonstrated excellent reliability (ICC > 0.90) and shows strong correlation with functional ability (36). The cutoff value is > 10 sec for 5 rep sitting to standing and standing to sitting transition
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
- Background: PubMed 34308899Senol D, Erdem C, Canbolat M, Toy S, Karatas T, Baykara RA, Ozbag D, Akyurek G. Comparison of the effects of conventional physiotherapy and proprioception exercises on pain and ankle proprioception in patients with lumbar radiculopathy. J Back Musculoskelet Rehabil. 2022;35(2):421-428. doi: 10.3233/BMR-200361.
- BackgroundAshraf B, Ahmad S, Ashraf K, Kanwal S, Ashraf S, Khan N, et al. Effectiveness of spinal mobilization with leg movement versus McKenzie back extension exercises in lumbar radiculopathy. 2021;15(5):1436-40.
- BackgroundFatima A, Mehmood Z, Ahmad SJJoIIMC. Effects of Mulligan Traction Straight Leg Raise Versus Passive Straight Leg Raise in Lumbar Radiculopathy Patients. 2022;17(2):86-90.
- BackgroundSingh V, Malik MJRJoN. Lumbar radiculopathy managed with spinal mobilization with leg movement: A case study. 2021;20(2):246-9.
- BackgroundNaidu SP, Srikantaiah S, Boyle RJIJoPT, Research. Immediate Effect of Mulligan's Spinal Mobilization with Limb Movements on Straight Leg Raise Test in Patients with Lumbar Radiculopathy: A Randomized Controlled Trial. 2023;5(1):66-72.
- BackgroundSingh V, Malik MJAiR. Effect of manual therapy on pain, disability and neural mobility in patients of lumbar prolapsed intervertebral disc: a randomized controlled trial. 2022;36(3):11-8.
- BackgroundYasmeen S, Ahmad Z, Ishtiaq NJJRCoRS. The comparative effects of Butler's neural tissue mobilization and Mulligan's Bent leg raise in patients with chronic lumbar radiculopathy. 2022;10(02).
- Background: PubMed 38137856Lin LH, Lin TY, Chang KV, Wu WT, Ozcakar L. Neural Mobilization for Reducing Pain and Disability in Patients with Lumbar Radiculopathy: A Systematic Review and Meta-Analysis. Life (Basel). 2023 Nov 26;13(12):2255. doi: 10.3390/life13122255.
- Background: PubMed 40260717Hussein H, Atteya M, Ansari A, Kamel E. A Systematic Review and Meta-Analysis of the Effectiveness of Mulligan Mobilization with Movement on Pain, Range of Motion, Function, and Flexibility in Patients with Sciatica. NeuroRehabilitation. 2025 Mar;56(2):83-96. doi: 10.1177/10538135241301693. Epub 2024 Dec 18.
- Background: PubMed 34719942George SZ, Fritz JM, Silfies SP, Schneider MJ, Beneciuk JM, Lentz TA, Gilliam JR, Hendren S, Norman KS. Interventions for the Management of Acute and Chronic Low Back Pain: Revision 2021. J Orthop Sports Phys Ther. 2021 Nov;51(11):CPG1-CPG60. doi: 10.2519/jospt.2021.0304.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Amna Zia, PhD principal investigator
King Edward Medical University
Muniba Tahir principal investigator
Riphah International University, Lahore Campus
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mulligan Bent Leg Raise (MBLR) and Spinal Mobilization With Leg Movement (SMWLM) in people with Lumbar Radiculopathy, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Amna Zia, PhD* (03244686993, amna.zia@kemu.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NPRS for pain (time frame: upto 4 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07726823, which also lists 10 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.