Clinical trials: Longevity
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Kidney Diseases, ESRD
Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
This is a multi-center clinical study in subjects requiring arteriovenous grafts in the upper extremity for hemodialysis access. All subjects will provide informed consent before undergoing any study procedures.
- Trial name
- NCT00448708
- Testing
- Vascular Wrap Paclitaxel-Eluting Mesh, Lifespan® ePTFE Vascular Graft
- Where
- 33 sites in United States
- Volunteers
- 222 people
- Sponsor
- Angiotech Pharmaceuticals
Heart Failure
Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)
This is a multicenter study to evaluate potential decrease in hospitalization events and time between events and increasing longevity in patients with symptomatic congestive heart failure and intolerant of first-line medication…
- Trial name
- NCT00090259
- Testing
- Losartan 50 mg, Losartan 150 mg
- Volunteers
- 3,834 people
- Sponsor
- Organon and Co
Health Personnel Attitude, Health Knowledge, Attitudes, Practice
Healthcare Provider Human Papillomavirus Education and Professional Skills Intervention
Healthcare providers (HCP) serving the El Paso U.S.-Mexico Border Region will be recruited to compare educational and professional skills interventions focused on the human papillomavirus (HPV).
- Trial name
- NCT05120869
- Testing
- Tailored HPV Education and Professional Skills Intervention Group, General HPV Education and Communication Skills Control Group
- Where
- 2 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Musculoskeletal Pain, Pain, Chronic
NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)
Musculoskeletal pain represents the leading cause of disability worldwide. It has been traditionally attributed to peripheral mechanisms, but peripheral damage, inflammation, and psychological factors have failed to significantly…
- Trial name
- NEPAL (NCT02488863)
- Testing
- MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires
- Where
- 4 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cardiovascular Disease
Expression of Longevity Genes in Response to Extended Fasting
The purpose of this study is to evaluate the effect of fasting on physical changes associated with cardiovascular disease.
- Trial name
- FEELGOOD (NCT01059760)
- Testing
- Fasting First, Fed First
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Osteoarthritis, Knee, Osteoarthritis, Hip
Resilience for Older Workers With OA Through Exercise
Exercise is effective at reducing pain while improving physical function. However we do not know if exercise can boost resilience in the workplace, to allow people with osteoarthritis to work as long as they desire.
- Trial name
- NCT02609672
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
End Stage Renal Disease
Dialysis Catheter Comparative Clinical Trial
The purpose of this clinical trial is to compare the longevity of two dialysis catheters.
- Trial name
- NCT00526123
- Testing
- Symmetric Tip Catheter, Conventional Split-tip Catheter
- Where
- 14 sites in United States
- Volunteers
- 599 people
- Sponsor
- Tyco Healthcare Group
Insulin Dependent Diabetes Mellitus 1
Longevity of Multi-Slitted Catheter With Lantern Technology
To determine time to set failure when the Convatec Inset II with Lantern technology (Convatec Lantern) infusion set with multi-slitted catheter is worn for up to 10 days
- Trial name
- Lantern (NCT03819634)
- Testing
- Inset II with Lantern Technology
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Vascular System Injuries, Lipid Metabolism Disorders
Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years
Women have a natural protection that gives them greater longevity. One hypothesis most commonly used is the estrogen protection in the premenopausal period.
- Conditions
- Vascular System Injuries, Lipid Metabolism Disorders, Endothelial Disfunction
- Trial name
- NCT01668836
- Testing
- Resveratrol, Caloric restriction
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Alzheimer Disease, Cognitive Decline
Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study
The investigators will conduct tau positron emission tomography (PET) scans on 125 adults using the radiopharmaceutical Flortaucipir F18 ([18F]AV-1451).
- Trial name
- NCT04080544
- Testing
- [18F]AV-1451, Positron Emission Tomography
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Neil M Rofsky, MD, MHA
Aging
Metformin in Longevity Study (MILES).
Metformin, an FDA approved first-line drug for the treatment of type 2 diabetes, has known beneficial effects on glucose metabolism.
- Trial name
- MILES (NCT02432287)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Osteoarthritis, Knee, Osteoarthritis, Hip
Improving Resilience and Longevity for Workers Through Exercise
The purpose of this study is to examine the impact of an OA-specific aerobic and strengthening exercise program, delivered within the workplace, on mobility, pain, physical capacity, and resilience among workers with knee or hip…
- Trial name
- NCT03050320
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging
Study of Acarbose in Longevity
The investigators are studying the effects of acarbose on muscle and adipose gene transcription in older adults.
- Trial name
- SAIL (NCT02953093)
- Testing
- Acarbose
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Extracorporeal Membrane Oxygenation
The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity
The purpose of this study is to assess the impact of scheduled fresh frozen plasma (FFP) administration on extracorporeal membrane oxygenation (ECMO) pump longevity in critically ill pediatric and neonatal patients.
- Trial name
- NCT01903863
- Testing
- Fresh frozen plasma
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Duke University
Diabetes Mellitus
Evaluation of the Accuracy of an Implanted Glucose Sensor
The purpose of this clinical investigation is to evaluate the accuracy of the Senseonics Continuous Glucose Monitoring System (Senseonics CGM System) measurements when compared with reference standard measurements The…
- Trial name
- PRECISEII (NCT02647905)
- Testing
- Continuous Glucose Monitoring System
- Where
- 9 sites in United States
- Volunteers
- 90 people
- Sponsor
- Senseonics, Inc.