Clinical trials: Liver Resection
Hepatocellular Carcinoma
A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
The goal of this clinical trial is to evaluate the efficacy and safety of camrelizumab plus apatinib as adjuvant therapy for patients with hepatocellular carcinoma at high risk of recurrence after radical resection or ablation.
- Trial name
- NCT06546280
- Testing
- Camrelizumab, Apatinib
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Zhujiang Hospital
Neoplasms
A Study of ADH300004 in Surgically Resected Primary or Metastatic Colorectal Cancer and Liver Biopsy, or Planned Hepatic Resection
5 fluorouracil (5 FU), one of the most actively investigated anti-cancer drugs, is rapidly inactivated by the enzyme dihydropyrimidine dehydrogenase (DPD). ADH300004 blocks DPD.
- Trial name
- NCT00264446
- Testing
- ADH300004
- Where
- United States
- Sponsor
- Adherex Technologies, Inc.
HCC
Artificial Intelligence and Hepatocellular Carcinoma
To identify new relevant biomarkers for HCC patients and their risk of recurrence. Radiomics data and computer-vision data will be explored for their ability to predict the presence of particular pathological signs of…
- Trial name
- ARTIHCC (NCT05637788)
- Testing
- CT Scan Radiomics Features Extraction
- Where
- Italy
- Volunteers
- 535 people
- Sponsor
- Humanitas Clinical and Research Center
Liver Metastases
Hepatoprotective Effect of Remote vs Local Preconditioning of Liver
The aim of this study is to evaluate hepatoprotective effect from ischemia-reperfusion injury of remote ischemic preconditioning of the liver against local ischemic preconditioning of the liver during human liver resections.
- Trial name
- NCT03130920
- Testing
- Preconditioning
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Dubrava
Hepatocellular Carcinoma
Adjuvant Transcatheter Arterial Chemoembolization Versus Adjuvant Systemic Chemotherapy for Hepatocellular Carcinoma
The purpose of this study is to determine that adjuvant systemic chemotherapy is superior to adjuvant transcatheter arterial chemoembolization(TACE) in prolonging recurrence free survival（RFS） in patients after radical resection…
- Trial name
- NCT02584556
- Testing
- systemic chemotherapy, Transcatheter Arterial Chemoembolization
- Sponsor
- Guangxi Medical University
Liver Neoplasms
Short Term Surgical Outcomes of Anatomical Versus Non Anatomical Laparoscopic Liver Resection for Liver Tumors
aimed to discuss the short term surgical outcomes of Anatomical versus Non anatomical laparoscopic Liver resection for Liver tumors.
- Trial name
- NCT06271109
- Testing
- Anatomical laparoscopic liver resection for liver neoplasms, Non-Anatomical laparoscopic liver resection for liver neoplasms
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Carcinoma, Hepatocellular
CIK Treatment for HCC Patient Underwent Radical Resection
This is a randomized controlled study. About 200 patients with hepatocellular carcinoma who underwent radical resection will be included.
- Trial name
- NCT01749865
- Testing
- Cytokine-Induced Killer Cells
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Liver Diseases, Surgery
Longitudinal Outcomes in Hepatic Resection
This observational registry of patients undergoing liver surgery collects patients both retrospectively and prospectively. Patients undergoing liver resection for any non-transplant indication will be evaluated for clinical…
- Trial name
- NCT02997098
- Where
- United States
- Sponsor
- Duke University
Pancreas Adenocarcinoma, Pancreas Metastases
Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX
This is a prospective, pilot study from a single center. Patients will be evaluated and operated on by one of five surgeons with a subspeciality in hepato-biliary and pancreatic surgery.
- Conditions
- Pancreas Adenocarcinoma, Pancreas Metastases, Pancreas Cancer
- Trial name
- PDAC-LIV (NCT06349278)
- Testing
- Pancreatic resection and non-anatomic liver resections.
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Laval University
Hepatocellular Carcinoma
A Trial of Licartin for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant Licartin therapy after resection.Patients receiving curative resection (R0) were randomized to postoperative Licartin group and no Licartin group.
- Trial name
- NCT00819650
- Testing
- Licartin (generic name,[131I]metuximab injection)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Occult Bleeding, Hemorrhage
A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage
Early detection of ongoing hemorrhage (OH) before onset of hemorrhagic shock is a universally acknowledged great unmet need, and particularly important after traumatic injury.
- Conditions
- Occult Bleeding, Hemorrhage, Hemorrhagic Shock
- Trial name
- NCT04814810
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Metastatic Colorectal Cancer
Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis
This Phase II study will recruit 17 colorectal cancer patients with liver-dominant metastases. All recruited patients will receive Sotevtamab at a dose of 800 mg once weekly for 6 cycles combined with FOLFOX once every 2 weeks…
- Trial name
- EGIA-003 (NCT06225843)
- Testing
- Sotevtamab, FOLFOX
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Alethia Biotherapeutics
Diaphragm Kinetics, Sarcopenia
Diaphragm Kinetics Following Hepatic Resection
Sarcopenia is associated with reduced pulmonary function in healthy adults, as well as with increased risk of pneumonia following abdominal surgery.
- Conditions
- Diaphragm Kinetics, Sarcopenia, Muscle Wasting, Liver Resection
- Trial name
- NCT04889235
- Testing
- Major liver resection
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- RWTH Aachen University
Hepatic Insufficiency
Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies
Extended hepatectomies of 4 or more segments are complicated by high rates of morbidity and mortality, mainly related to hepatic liver failure.
- Trial name
- SCINTIVOL (NCT02753517)
- Testing
- Hepatobiliary scintigraphy
- Where
- 12 sites in France
- Volunteers
- 326 people
- Sponsor
- University Hospital, Lille
Hyperlactacidemia
Sodium Bicarbonate Ringer's Solution for Preventing and Treating Hyperlactacidemia During Hepatectomy
A variety of reasons lead to a sharp increase in lactic acid levels in patients undergoing liver resection, while leading to hyperlactic acidemia, resulting in decreased cardiac output, elevated blood potassium, and response to…
- Trial name
- NCT04547296
- Testing
- Sodium Bicarbonate Ringer's Solution
- Where
- 7 sites in China
- Volunteers
- 484 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Adult Hepatocellular Carcinoma, Recurrent Hepatocellular Carcinoma
Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence
This single-centered phase II clinical study is to obtain preliminary information on 1-year recurrence-free survival rate, recurrence-free survival and safety profile of thalidomide in combination with tegafur-uracil in…
- Conditions
- Adult Hepatocellular Carcinoma, Recurrent Hepatocellular Carcinoma, Adverse Reaction to Drug, Vascular Endothelial Growth Factor Overexpression
- Trial name
- NCT02447679
- Testing
- thalidomine, tegafur-uracil
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Pancreas Cancer With Hepatic Metastase, Pancreas Adenocarcinoma
Hepatic Artery Infusion Pump Chemotherapy for Liver Metastases From Resected Pancreatic and Duodenal Adenocarcinoma
The goal of this observational study is to evaluate whether hepatic artery infusion pump (HAIP) chemotherapy can improve outcomes in patients with pancreatic or duodenal adenocarcinoma who have isolated or liver-dominant…
- Conditions
- Pancreas Cancer With Hepatic Metastase, Pancreas Adenocarcinoma, Duodenal Cancer, Duodenal Adenocarcinoma
- Trial name
- NCT07845617
- Testing
- Hepatic Artery Infusion Pump (HAIP), Floxuridine (FUDR)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- AdventHealth
Chronic Hepatitis b, Hepatic Carcinoma
The Investigation of Peginterferon Alfa-2a on the RFS of the Subjects With HCC Who Have Been Treated by Resection
The current study is a prospective, randomized, open, multi-center investigation. The aim of current study is to investigate whether the Recurrence-free Survival Rate (RFS）of the hepatitis B related -hepatocellular carcinoma…
- Trial name
- NCT03253250
- Testing
- ETV；TDF；ADV, Peginterferon Alfa-2a
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Huashan Hospital