Clinical trials: Liver Resection
Central Venous Pressure, Hepatectomy
Preoperative Sildenafil Administration for Hepatectomy
Hepatectomy is an important treatment for liver diseases, and bleeding is one of the most common complications during dissection of the liver parenchyma.
- Conditions
- Central Venous Pressure, Hepatectomy, Hemodynamics Instability, Sildenafil
- Trial name
- NCT06237751
- Testing
- Sildenafil 100 MG
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Hepatocellular Carcinoma
Hepatectomy Combined With Camrelizumab and Apatinib in CNLC Stage IIIb HCC
This study intends to prospectively enroll CNLC stage IIIb HCC cases with extrahepatic metastasis and intrahepatic lesions that are expected to be radical resected in several domestic clinical centers, and observe the OS and ORR…
- Trial name
- NCT05062837
- Testing
- Hepatectomy Combined With Camrelizumab and Apatinib
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Reperfusion Injury
Role of Volatile Anesthetics for Hepatic Protection
This study aims to evaluate the attenuation of ischemic-reperfusion injury in the liver after sevoflurane preconditioning. In the presence of sevoflurane, an attenuation of liver injury is hypothesized (diminished increase of…
- Trial name
- NCT00516711
- Testing
- Sevoflurane
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Zurich
Hepatocellular Carcinoma
A Novel Immunotherapy PD-1 Antiboty to Suppress Recurrence of HCC Combined With PVTT After Hepatic Resection
Hepatic resection is the most effective curative treatment for resectable HCC, whereas frequent recurrence usually impaired the efficacy of hepatic resection and contributed poor survivals.
- Trial name
- NCT03914352
- Testing
- PD-1 antibody, TACE
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cancer Hospital of Guangxi Medical University
Hepatocellular Carcinoma
A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant TACE after resection.Patients receiving curative resection (R0) were randomized to postoperative TACE group and no TACE group.
- Trial name
- NCT00820053
- Testing
- epirubicin and lipiodol
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Carcinoma, Hepatocellular, Liver Dysfunction
Evaluation of Remnant Liver Function Using Primovist-enhanced MRI Before Resection/Ablation of Hepatocellular Carcinoma
The purpose of this study is to determine whether the global and segmental hepatic uptake and excretion of Gd-EOB-DTPA on Gd-EOB-DTPA-enhanced liver MRI correlates with standard liver function test results in the patients with…
- Trial name
- LiFE (NCT01490203)
- Testing
- Gd-EOB-DTPA, MRI
- Where
- 4 sites in South Korea
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Introduction Adult living related donor hepatectomy is associated with pain due to the sub-costal j-shaped incision, rib retraction using Thompson retractor, and diaphragm irritation1.
- Trial name
- NCT04151511
- Testing
- Continuous Erector Spinae Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa Clinical Research Center
Liver Cancer
Efficacy of TEAS on Chronic Pain and Survival in Patients Undergoing Hepatectomy
This study is a further observation and follow-up of the patients enrolled in the registration number NCT06341270 to further evaluate the efficacy of TEAS on postoperative chronic pain, quality of life and survival rate in…
- Trial name
- NCT06406244
- Testing
- TEAS group
- Where
- China
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Liver Cancer
Effects of Antiviral Therapy on HBV Reactivation
Hepatitis B virus (HBV) reactivation happens after liver resection for HBV-related hepatocellular carcinoma (HCC) patients, particularly for those with positive serum HBV-DNA .
- Trial name
- HBV-DNA(-) (NCT02829359)
- Testing
- Entecavir therapy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Liver Cirrhosis
Evaluation of Liver Regeneration With Autologous Peripheral Stem Cells
For patient with liver cirrhosis who need to right or extended right hepatectomy, we will treat with autologous peripheral stem cells transplantation to facilitate liver regeneration.
- Trial name
- NCT01108380
- Testing
- Plasma pheresis, Right portal vein embolization
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Some Studies Shows That the Steroid Can Reduce the Injury of the I/R of the Liver
Prospective Randomized Study of Glucocorticoids in the Impact of the Liver Function and the Prognosis After Hepatectomy of HCC
The major drawback of hepatic pedicle clamping is ischaemia-reperfusion injury with impairment of liver function. Perioperative steroid administration has been advocated to reduce liver damage.
- Trial name
- NCT01608945
- Testing
- Hydrocortisone sodium succinate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Patients Receiving Hepatectomy Under General Anesthesia
Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection
Efficient postoperative pain control plays a vital part in the management of patients after surgery. In particular, major surgeries including hepatectomy cause intense postoperative pain that may result in cardiovascular or…
- Trial name
- NCT05208801
- Testing
- Percutaneous injection, Morphine, Morphine+Bupivacaine
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pulmonary Embolism, Venous Thrombosis
Incidence of Venous Thromboembolic Disease and Portal Vein Thrombosis After Hepatectomy. A Cohort Study.
Observational. Retrospective cohort.
- Conditions
- Pulmonary Embolism, Venous Thrombosis, Portal Thrombosis
- Trial name
- NCT02597218
- Where
- Argentina
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Hepatocellular Carcinoma
Clinical Study Examining the Safety and Efficacy of Doxorubicin Drug Eluting Microspheres Transarterial Embolization in the Setting of Hepatocellular Carcinoma (HCC)
The study is designed to determine whether loading doxorubicin (a type of chemotherapy), when loaded onto a drug eluting microsphere will result in increased destruction of a tumor.
- Trial name
- NCT01116635
- Testing
- doxorubicin, superabsorbent polymer microspheres, embolotherapy
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Donor Hepatectomy, Serum Lactate
Effect of Preoperative Carbohydrate Loading on Serum Lactate Levels in Patients Undergoing Donor Hepatectomy
This randomized controlled trial investigated whether preoperative carbohydrate loading reduces perioperative serum lactate levels in patients undergoing donor hepatectomy.
- Conditions
- Donor Hepatectomy, Serum Lactate, Preoperative Carbohydrate Loading
- Trial name
- NCT07723391
- Testing
- Preoperative Carbohydrate Loading
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Gastrointestinal Hemorrhage, Postoperative Hemorrhage
The Major Bleeding Risk Following Hepatectomy
This study examined long-term incidence rates of major bleeding associated with hepatectomy. The investigators used data from Taiwan's National Health Insurance Research Database.
- Conditions
- Gastrointestinal Hemorrhage, Postoperative Hemorrhage, Surgery--Complications
- Trial name
- NCT04748081
- Testing
- hepatectomy
- Where
- Taiwan
- Volunteers
- 5,265 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Pain
A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy
This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for…
- Trial name
- NCT06553495
- Testing
- Nerve block
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jie Chen