PainNCT06553495
A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy
A study testing Nerve block in people with Pain, run by Jie Chen at 1 site in China.
Trial summary
This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery. Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Pain
- What is being tested?
- Nerve block
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 80 participants
- Where
- 1 siteChina
- Study dates
- 1 Aug 2024to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 1.18-80 years old adult, BMI<27.9kg/m2
- 2: 2. American Society of Anesthesiologists ASA Grade I-III
- 3: 3. Patients with laparoscopic partial liver resection such as liver tumors
- 4: 4. Willing to participate in this study and sign the informed consent form
- -
Who cannot join
- 1. The patient or family member refuses to sign the informed consent form
- 2. Blood coagulation dysfunction, local infection
- 3. Those who have communication, communication disorders or mental abnormalities
- 4. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases
- 5. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.
- -
Trial locations and contacts
1 site in 1 country.
China1 site
The Second Affiliated Hospital Of Chongqing Medical University
Chongqing, Chongqing Municipality, 400000
About this study
This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.
Read the detailed description
This study was a prospective, double-blind, randomized controlled trial. Patients who were eligible for laparoscopic partial liver resection in our center were included, with intertransverse nerve block as the experimental group and paravertebral nerve block as the control group. Through the analysis of postoperative pain score 30min to 24h, the number of effective analgesic pump compressions within 24h, the amount of analgesic drugs used, complications and other data, To evaluate the efficacy and safety of intertransverse nerve block in patients undergoing laparoscopic partial liver resection.
- Conditions
- Pain
- Being tested
- Nerve block
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nerve blockOther
Analgesic effect of different nerve blocks
| Study group | Role | What they receive |
|---|---|---|
| intertransverse nerve block | Experimental | To study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy Receives: Other: Nerve block |
| paravertebral nerve block | Placebo comparator | To study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy Receives: Other: Nerve block |
What is being measured
The primary outcome is the main question the study is designed to answer.
The number of effective compressions of the analgesic pump within 24 hours after surgery
Measured: Within 24 hours after the operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2024
- Study start1 Aug 2024
- Primary completion30 Nov 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Jie Chen
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Jie Chen, The Second Affiliated Hospital of Chongqing Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06553495
- Sponsor's protocol ID
- 2024-098
- Status last verified
- Aug 2024
- First submitted
- 12 Aug 2024
- Last updated
- 14 Aug 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Aug 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy
- ClinicalTrials.gov ID
- NCT06553495
- Acronym / sponsor ID
- 2024-098
- Conditions
- Pain
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Jie ChenUniversity, hospital or other
- Study start
- 1 Aug 2024 (actual)
- Primary completion
- 30 Nov 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 14 Aug 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the analgesic effect of intertransverse nerve block and paravertebral nerve block after endoscopic hepatectomy, evaluate its effectiveness and safety, and provide new ideas and clinical basis for postoperative pain management of liver surgery.
Detailed description
This study was a prospective, double-blind, randomized controlled trial. Patients who were eligible for laparoscopic partial liver resection in our center were included, with intertransverse nerve block as the experimental group and paravertebral nerve block as the control group. Through the analysis of postoperative pain score 30min to 24h, the number of effective analgesic pump compressions within 24h, the amount of analgesic drugs used, complications and other data, To evaluate the efficacy and safety of intertransverse nerve block in patients undergoing laparoscopic partial liver resection.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intertransverse nerve block | Experimental | Other: Nerve blockTo study the analgesic effect of intertransverse nerve block after endoscopic hepatectomy |
| paravertebral nerve block | Placebo comparator | Other: Nerve blockTo study the analgesic effect of paravertebral nerve block after endoscopic hepatectomy |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- 1.18-80 years old adult, BMI<27.9kg/m2
- 2: 2. American Society of Anesthesiologists ASA Grade I-III
- 3: 3. Patients with laparoscopic partial liver resection such as liver tumors
- 4: 4. Willing to participate in this study and sign the informed consent form
- -
Key exclusion criteria (6 listed)
- 1. The patient or family member refuses to sign the informed consent form
- 2. Blood coagulation dysfunction, local infection
- 3. Those who have communication, communication disorders or mental abnormalities
- 4. Patients with severe heart, pulmonary and renal insufficiency or patients with central system diseases
- 5. For any reason, it cannot be matched with the study or the researcher believes that it is not appropriate to be included in this experiment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nerve blockAnalgesic effect of different nerve blocks | Other | intertransverse nerve block, paravertebral nerve block |
Primary outcome
The number of effective compressions of the analgesic pump within 24 hours after surgery
Time frame: Within 24 hours after the operation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Aug 2024.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nerve block in people with Pain, run by Jie Chen at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 14 Aug 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The number of effective compressions of the analgesic pump within 24 hours after surgery (time frame: Within 24 hours after the operation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Aug 2024.