Clinical trials: Liver Resection
Neoplastic Disease, Solid Tumor
Indocyanine Green (ICG) Guided Tumor Resection
This is a study to assess the ability of Indocyanine Green (ICG) to identify neoplastic disease. For many pediatric solid tumors, complete resection of the primary site and/or metastatic deposits is critical for achieving a cure.
- Trial name
- NCT04084067
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- St. Jude Children's Research Hospital
Hepatic Ischemia
Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy
Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of…
- Trial name
- NCT05830136
- Testing
- sodium bicarbonate Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Liver Resection
A Trial to Compare Pringle Maneuver With Either Infrahepatic Inferior Vena Cava Clamping or Low Central Venous Pressure
The purpose of this study is to better comprehend the benefits and efficacy of portal triad clamping with infrahepatic IVC clamping during complex hepatectomy.
- Trial name
- NCT01355887
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Huazhong University of Science and Technology
Hepatocellular Carcinoma
A Novel Laparoscopic Hepatectomy Posture, Left Lateral Position Plus Jackknife Position
Since the first report of laparoscopic resection of a benign hepatic tumor by Professor H. Reith in 1991, the laparoscope has been widely used in liver disease.
- Trial name
- NCT02809287
- Testing
- Jackknife posture
- Volunteers
- 10 people
- Sponsor
- Sun Yat-sen University
Hepatic Cancer, Hepatic Resection
Immunohistochemical Algorithm for the Diagnosis and Classification of Hepatocellular Carcinomas With TERT, TP53 and CTNNB1 Mutation
The presence of certain mutations in HCC, such as TERT and TP53, have a suspected or proven prognostic role in resected patients, but lack a morphological or immunophenotypic counterpart, which would allow us to define which…
- Trial name
- NCT06718153
- Testing
- Immunohistochemistry and in situ hybridisation analysis
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hepatic Carcinoma
Liver Resection for Patients With Hepatocellular Carcinoma and Clinically Significant Portal Hypertension
Clinically significant portal hypertension limits the therapeutic options for hepatocellular carcinoma (HCC), which is closely associated with patient prognosis.
- Trial name
- NCT06245798
- Testing
- transarterial chemoembolisation
- Where
- 2 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Tang-Du Hospital
Hepatocellular Carcinoma, Cirrhosis
Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis
Surgical resection is the most effective treatment of primary and secondary liver tumors. Technical innovations have mainly focused on minimizing bleeding during transection of the hepatic parenchyma because excessive hemorrhage…
- Trial name
- NCT01992978
- Testing
- Radiofrequency-assisted Hepatectomy, Conventional Hepatectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
The Characteristics of CRLM Patients Who Would Benefit More From Anatomical Resection
Anatomical Resection in Colorectal Liver Metastases Patients
The type of liver resection (anatomical resection, AR or nonanatomical resection, NAR) for colorectal liver metastases (CRLM) is subject to debate.
- Trial name
- NCT05673564
- Testing
- Anatomical Resection
- Volunteers
- 729 people
- Sponsor
- Fudan University
Liver Cancer
Sho-Saiko-To Following Removal of Liver Cancer By Embolization in Treating Patients With Liver Cancer That Cannot Be Surgically Removed
RATIONALE: The Chinese herbal medicine Sho-saiko-to contains ingredients that may slow the growth of tumor cells and stimulate a person's immune system to help kill tumor cells.
- Trial name
- NCT00040898
- Testing
- Sho-saiko-to
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hepatocellular Carcinoma
Treatment for Patients With Multiple Hepatocellular Carcinomas Based on the NDR Scoring System
The aim of this study is to establish a selection criteria of hepatectomy for patients with multiple hepatocellular carcinomas based on the NDR Scoring System
- Trial name
- NCT02525952
- Testing
- Hepatectomy, TACE
- Where
- 2 sites in China
- Volunteers
- 320 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Liver Neoplasm, Kidney Injury, Acute
Perioperative Myocardial and Renal Injury in Patients Undergoing Hepatic Resection
Liver surgeries are high risk surgeries that might result in injuries in kidneys and heart. This study was planned to investigate the frequency of these injuries as well as the risk factors for their devolopment and its effect on…
- Conditions
- Liver Neoplasm, Kidney Injury, Acute, Myocardial Injury After Non-Cardiac Surgery
- Trial name
- NCT06775158
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Istanbul Saglik Bilimleri University
Colorectal Cancer, Liver Metastasis Colon Cancer
Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN
This will be the first trial testing the feasibility of working simultaneously with the two fluorescent dyes ICG and SGM-101 in 10 patients with colorectal metastases.
- Conditions
- Colorectal Cancer, Liver Metastasis Colon Cancer, Image
- Trial name
- FOCUS GREEN (NCT05965817)
- Testing
- SGM-101 op top of ICG
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Leiden University Medical Center
Hepatocellular Carcinoma
Efficacy of Sequential TACE and PVE on the Resectability of Hepatitis B Related HCC
A primary hepatocellular carcinoma (HCC) is generally regarded as unresectable if the future liver remnant (FLR)≤40％ of total liver volume in patient with underlying liver disease, such as hepatitis B.
- Trial name
- TACEPVE (NCT00834158)
- Testing
- TACE, PVE
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Hemorrhage
Infrahepatic Inferior Vena Cava Clamping During Hepatectomy
Intraoperative blood loss is a major concern during hepatic resection, as it has been shown to adversely affect patients' perioperative outcome.
- Trial name
- IVC CLAMP (NCT00732979)
- Testing
- Infrahepatic inferior vena cava clamping, No infrahepatic inferior vena cava clamping
- Where
- Germany
- Volunteers
- 152 people
- Sponsor
- Heidelberg University
Insulin Resistance
Surgical Stress After Laparoscopic Compared to Open Liver Resection
The purpose of this study is to determine whether the postoperative insulin resistance and cytokine release would be attenuated in laparoscopic compared with open liver resection.
- Trial name
- NCT01819688
- Testing
- laparoscopic liver resection
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Sir Run Run Shaw Hospital
Intrahepatic Cholangiocarcinoma
Role of Bile Duct Resection in Major Hepatectomy Due to Intrahepatic Cholangiocarcinoma
To investigate the prognosis due to presence or absence of bile duct resection in intrahepatic cholangiocarcinoma that require hepatic lobectomy.
- Trial name
- NCT01862276
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Kansai Hepatobiliary Oncology Group
Acute Pain
Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy
Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in…
- Trial name
- NCT02645903
- Testing
- Transversus Abdominis Plane Block, standard general anesthesia
- Volunteers
- 50 people
- Sponsor
- Inonu University
Cholangiocarcinoma
Liver Resection Versus Radio-chemotherapy-Transplantation for Hilar Cholangiocarcinoma
A prospective, open-label, randomised, multicentre, comparative study in two parallel groups comparing an interventional group with liver transplantation preceded by neoadjuvant radio-chemotherapy and a control group receiving…
- Trial name
- TRANSPHIL (NCT02232932)
- Testing
- CAPECITABINE-Radiotherapy -Liver Transplantation, RESECTION
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pathologic Stage I Gastric Cancer AJCC v8, Colorectal Cancer
Clinical Trial to Evaluate the Efficacy and Safety of a Thoracic and Abdominal Endoscopic Surgical System
Evaluation of the efficacy and safety of thoracic and abdominal endoscopic surgical systems manufactured by Shenzhen Cornerstone Robotics Technology Co., Ltd. for use in general, gynaecological and thoracic surgical procedures.
- Conditions
- Pathologic Stage I Gastric Cancer AJCC v8, Colorectal Cancer, Esophageal Cancer, Hepatectomy
- Trial name
- NCT06587152
- Testing
- Robot-assisted surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cornerstone Robotics
Neuroendocrine Tumor G1 (NET G1)/Carcinoid, Neuroendocrine Tumor Grade 2
Comparison of Adjuvant Treatment With 177Lu-DOTATATE to Best Supportive Care in Patients After Resection of Neuroendocrine Liver Metastases
An international multi-centre, open, randomised, parallel-group phase II study comparing adjuvant treatment with 177Lu-DOTATATE to best supportive care in patients after complete surgical removal of neuroendocrine liver…
- Conditions
- Neuroendocrine Tumor G1 (NET G1)/Carcinoid, Neuroendocrine Tumor Grade 2, Neuroendocrine Tumors, Liver Metastases
- Trial name
- NELMAS (NCT05987176)
- Testing
- Lutathera
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Imperial College London