Clinical trials: Lidocaine Infusion
Sleep Disturbance
Perioperative Lignocaine and Sleep Disturbance
The aim of this clinical trial is to study the effect of an intravenous infusion of lidocaïne in a multimodal analgesic protocol on the architecture sleep during the first postoperative night.
- Trial name
- NCT03317912
- Testing
- Lidocaïne 2%
- Volunteers
- 40 people
- Sponsor
- University of Liege
Thyroid Disease, Thyroid Surgery
Continuous Lidocaine Infusion in Thyroid Surgery Using Intraoperative Neurophysiological Monitoring
Thyroid surgery is a common procedure for the treatment of thyroid tumors, nodules and other related lesions. During this procedure, intraoperative neurophysiological monitoring is used to protect the recurrent laryngeal nerves.
- Conditions
- Thyroid Disease, Thyroid Surgery, Lidocaine Infusion
- Trial name
- NCT06785987
- Testing
- Continuous Lidocaine Infusion, intermittent fentanyl infusion, Continuous remifentanil Infusion
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Veterans General Hospital.
PONV, Opioid Sparing Anaesthesia
Opioid Sparing Anaesthesia for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
In spite of multimodal analgesic strategies, which consist of opioids, dexamethasone, non-steroidal anti-inflammatory drugs, and local anesthetics applied into the surgical wound, postoperative pain and postoperative nausea and…
- Trial name
- NCT04706897
- Testing
- Dexmedetomidine, ketamine and lidocaine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Lidocaine, Analgesia
Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection.
- Conditions
- Lidocaine, Analgesia, Pain, Postoperative, Thoracic Surgery
- Trial name
- NCT05901389
- Testing
- Lidocaine, Sufentanil
- Where
- China
- Volunteers
- 451 people
- Sponsor
- Qilu Hospital of Shandong University
Lidocaine, Dexmedetomidine
Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery
This study aims to compare lidocaine and dexmedetomidine infusion and their combination on perioperative pain in patients undergoing video-assisted thoracoscopic surgery.
- Conditions
- Lidocaine, Dexmedetomidine, Infusion, Perioperative Pain
- Trial name
- NCT06837519
- Testing
- Lidocaine, Dexmedetomidine, Lidocaine and Dexmedetomidine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Sevoflurane, Lidocaine
Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy
This study will be conducted to evaluate the effects of different anesthetic modalities [sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)] on intracranial pressure…
- Conditions
- Sevoflurane, Lidocaine, Propofol, Intracranial Pressure
- Trial name
- NCT07062367
- Testing
- Propofol, Sevoflurane plus lidocaine infusion, Sevoflurane
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Pain
Intrauterine Lidocaine Infusion for Essure Sterilization Procedures
The purpose of this study is to assess the level of pain women experience with an Essure procedure and the effect that lidocaine might have on that pain.
- Trial name
- NCT00613834
- Testing
- Lidocaine, Sterile Saline
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Neurocognitive Function of Elderly Patients
Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP).
dexmedetomidine infusion or lidocaine infusion starting before induction of intravenous general anesthesia and continue as infusion intraoperative can reduce postoperative cognitive dysfunction incidence (primary outcome)…
- Trial name
- NCT07497009
- Testing
- Dexmedetomidine, lidocaine, normal saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Chronic Cholecystitis
Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy
Opioids may attenuate postoperative hyperalgesia and postoperative nausea and vomiting. Our hypothesis is: opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic…
- Trial name
- NCT01833819
- Testing
- Dexmedetomidine and lidocaine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Orofacial Pain
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
A prospective, randomized, double-blind clinical trial comparing the safety and efficacy of intravenous lidocaine, ketamine, and their combination as treatment options for patients suffering from treatment-resistant orofacial…
- Trial name
- NCT07250867
- Testing
- Lidocaine Intravenous Infusion, Ketamine intravenous infusion, Combined lidocaine and ketamine intravenous infusion
- Volunteers
- 105 people
- Sponsor
- Assiut University
Opioid-use Disorder, Opioid Use
The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis
Pregnant women with a history of opioid use disorder, chronic opioid use or those who are on medication assisted treatment will be randomly assigned to receive either a sub-fascial continuous infusion of bupivacaine or…
- Conditions
- Opioid-use Disorder, Opioid Use, Opioid Dependence, Opioid Abuse
- Trial name
- NCT04033562
- Testing
- Lidocaine patch, Ambu ACTion pump, 0.125% bupivacaine at 8cc/hr
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Postoperative Pain Management
Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study
The purpose of this study is to evaluate the safety and efficacy of lidocaine infusion in acute pain management following open abdominal surgery, including opiate use after surgery and the incidence of postoperative nausea and…
- Trial name
- NCT06725485
- Testing
- Low-Dose Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Methodist Hospital Research Institute
Colorectal Cancer
Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality…
- Trial name
- NCT06405776
- Testing
- lidocaine
- Where
- China
- Volunteers
- 276 people
- Sponsor
- West China Hospital
Lidocaine, Dexmedetomidine
Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV
BACKGROUND: Few researches have manifested that intravenous (IV) lidocaine or dexmedetomidine decreased the incidence of postoperative nausea and vomiting (PONV).
- Conditions
- Lidocaine, Dexmedetomidine, Nausea and Vomiting, Postoperative
- Trial name
- NCT03788018
- Testing
- lidocaine and dexmedetomidine IV, saline IV
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xu Siqi
Post Operative Pain, Hemodynamic Instability
Comparison of the Effect of Lidocaine Infusion Applied at Different Doses During Lumbar Spinal Surgery on Hemodynamics and Postoperative Pain
The aim of this study is to investigate the effects of intravenous infusion of lidocaine at different doses (1 mg/kg/h vs. 2 mg/kg/h) in the intraoperative period in patients undergoing lumbar stabilization, whether postoperative…
- Conditions
- Post Operative Pain, Hemodynamic Instability, Opioid Use
- Trial name
- NCT05936190
- Testing
- Lidocaine IV, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Bariatric Surgery, Lidocaine
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours.
- Conditions
- Bariatric Surgery, Lidocaine, Dexmedetomidine
- Trial name
- NCT07327905
- Testing
- intravenous lidocaine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Total Knee Arthroplasty
Treatment of Postoperative Pain After Total Knee Arthroplasy Using Intravenous Lidocaine Infusion
Total knee replacement is often associated with severe postoperative pain, especially in the first 24 hours. Patient controlled analgesia (PCA) and continuous femoral block with PCA are commonly used to treat postoperative pain…
- Trial name
- NCT00616850
- Testing
- Continuous femoral catheter block, Lidocaine, Preservative free normal saline
- Where
- United States
- Sponsor
- Loma Linda University
Midline Catheter, Lidocaine Infusion
Outpatient Midline Catheter in Patients Receiveing Lidocaine Infusion Series.
This study will assess the efficacy, safety and practicality of using midline catheters for repeated intravenous lidocaine infusions in an outpatient pain management setting.
- Conditions
- Midline Catheter, Lidocaine Infusion, Chronic Pain, Outpatient
- Trial name
- Midline Lid (NCT07555314)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Medical University of Warsaw
Lumbar Disc Herniation
Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility
Intra-operative blood loss is an important attribution and predictor of the lumbar spine surgery and patient outcome. Stripping the muscle off bone makes more exposed bleeding spine surface is one of causes for blood loss during…
- Trial name
- NCT04260685
- Testing
- Lidocaine, Esmolol
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Enhanced Recovery, Functional Endoscopic Sinus Surgery
Lidocaine Infusion Versus Magnesium Infusion in Decreasing Fentanyl Requirements in Endoscopic Sinus Surgeries
Enhanced recovery after ear, nose and throat surgery is based on multimodal and multidisciplinary perioperative interventions to decrease postoperative pain.
- Conditions
- Enhanced Recovery, Functional Endoscopic Sinus Surgery, Lidocaine, Magnesium Sulphate
- Trial name
- NCT06966102
- Testing
- Lidocaine group, Magnesium group, Control group
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Cairo University