Clinical trials: Lacerations
Rotator Cuff Tendinosis, Rotator Cuff Injuries
Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL)
The aim of this study will be to compare the effectiveness of an exercise therapy program with extracorporeal shockwave therapy, ultrasound-guided percutaneous irrigation and a wait and see approach in people with rotator cuff…
- Conditions
- Rotator Cuff Tendinosis, Rotator Cuff Injuries, Shoulder Tendinitis, Calcific Shoulder Tendinitis
- Trial name
- EFFECT (NCT05478902)
- Testing
- Exercise Therapy, Extracorporeal Shockwave Therapy, Ultrasound-Guided Percutaneous Irrigation
- Where
- 2 sites in Spain
- Volunteers
- 116 people
- Sponsor
- University of Valencia
Rotator Cuff Tear
An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS
The prognosis for patients with large rotator cuff tears is poor. This recently developed biologic scaffold provides numerous structural and functional properties that may direct cell growth and aid in tendon healing.
- Trial name
- NCT00182299
- Testing
- porcine small intestine submucosa (SIS)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Hamilton Health Sciences Corporation
Parturition, Delivery, Obstetric
Randomized Controlled Trial of the Effectiveness of Perineal Pain and Security of the Suture Led by the Result of Hemostasis Versus Manual Compression Routine Suture Perineal Tears of First Degree During Childbirth
During childbirth, the recommendations have evolved to a restriction of episiotomy. This reduction results in an increase of superficial vaginal and perineal tears.
- Trial name
- ImSOLENCE (NCT02870712)
- Testing
- Suture of perineum, hemostatis by digital compression
- Where
- France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hand Laceration, Tendon Involved
Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon
The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.
- Conditions
- Hand Laceration, Tendon Involved, Clean Laceration, No Bone Involved
- Trial name
- NCT01899781
- Testing
- Antibiotic-Cefamezin
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Dry Eye Syndrome
Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES
Dry eye disease (DED) is a multifactorial condition often exacerbated by cataract surgery, leading to discomfort and visual disturbances.
- Trial name
- NCT06914232
- Testing
- Warm Compress, Standard Care
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Superior University
Dry Eye Syndrome
Correlation of Different Signs for Assessment of Dry Eye Syndrome
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response of the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01753687
- Testing
- Ocular scattering of the tear film, Optical Coherence Tomography (OCT), Measurement of tear film osmolarity
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Keratoconjunctivitis Sicca
Effect of Controlled Adverse Environment (CAE) on Tear Film Stability
The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.
- Trial name
- NCT01547936
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ORA, Inc.
Hip Impingement Syndrome, Acetabular Labral Tear
Weight Bearing Status Post-hip Arthroscopy
This study is being proposed to examine weight bearing precautions following hip arthroscopic labral repair, femoroplasty, and capsular closure.
- Trial name
- NCT05720806
- Testing
- Weight Bearing as tolerated (WBAT) immediately following surgery., Flat foot weight bearing (FFWB) immediately following surgery
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Pittsburgh
Shoulder Pain, Shoulder Injuries
MDR SureLock All-Suture Anchor
To report the outcomes of a series of patients with recurrent anterior and/or posterior shoulder instability who underwent surgical repair of the affected labrum using the SureLock all-suture anchor.
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Disease, Shoulder Pain Chronic
- Trial name
- NCT04093700
- Testing
- SureLock All-Suture Anchor
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Zimmer Biomet
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Dry Eye, Dry Eye Syndromes
Tear Production by Nasal Neurostimulation Compared to Active Control
This crossover design study evaluates the effectiveness of the Oculeve Intranasal Neurostimulator comparing the effect of intranasal (active) versus extranasal (control) stimulation on tear production as measured by the Jones…
- Conditions
- Dry Eye, Dry Eye Syndromes, Keratoconjunctivitis Sicca
- Trial name
- NCT02970799
- Testing
- Intranasal Neurostimulator
- Volunteers
- 27 people
- Sponsor
- Oculeve, Inc.
Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs)
Platelet-Rich Plasma for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether platelet-rich plasma (PRP) injection, made from a participant's own blood, can help heal the tendon and improve shoulder symptoms in people with partial tears of the…
- Conditions
- Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs), Rotator Cuff Injury
- Trial name
- OPTIMISE (NCT07659600)
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 100 people
- Sponsor
- Universidade Nova de Lisboa
Dry Eye
Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion
The primary objective of this investigation will be to quantify the increase in tear film break-up time (TFBUT) associated with the instillation of a single eyedrop of an Ocular Emulsion in dry eye sufferers.
- Trial name
- NCT01368198
- Testing
- Systane Balance Lubricating Eye Drops, OPTIVE™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Tear, Dry Eye Syndromes
Effect of ADDE on Tear Interferometry
Importance: Lipid layer thickness (LLT) reflects the lipid components of tear film, but is affected by the mucocutaneous components.
- Trial name
- NCT05456061
- Testing
- 3% diquafosol eyedrops, Silicone punctal plug insertion
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Yonsei University
Rotator Cuff Tear
Longitudinal Study of Asymptomatic Rotator Cuff Tears
The purpose of this study is to analyze the natural course of asymptomatic rotator cuff tears.
- Trial name
- NCT01085942
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vestre Viken Hospital Trust
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Zone 2 Flexor Tendon Lacerations of the Hand
The Effects of a Stainless Steel Suture MGH Flexor Tendon Repair Coupled With Early Aggressive Range of Motion Rehabilitation: a Randomized Controlled Trial
The investigators are comparing the combination of a stainless steel repair and aggressive early active range of motion rehabilitation protocol for flexor tendon lacerations in the hand with a current, accepted treatment offered…
- Trial name
- NCT01344980
- Testing
- Stainless steel suture, Polypropylene suture, Aggressive early active range of motion rehabilitation
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Rotator Cuff Tear
Sonoelastography to Predict Rotator Cuff Tears
Large-to-massive rotator cuff tears accounts for 30% of all rotator cuff tears. These problems can be solved by surgeries, but only part of them can be completely repaired.
- Trial name
- NCT03682679
- Testing
- Sonoelastography
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Rotator Cuff Tear Repair
TASK-ORIENTED REHABILITATION AFTER ROTATOR CUFF SURGERY
Rotator cuff tears negatively affect shoulder stability, range of motion, and performance in daily activities. Postoperative rehabilitation is essential for improving functional recovery and quality of life; however, conventional…
- Trial name
- NCT07665541
- Testing
- Task-oriented rehabilitation, Conventional rehabilitation group
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Medipol University
Obstetric Trauma, Infections
Oral Antibiotics After Obstetric Perineal Tear
The purpose of this study is to investigate if 3 dose of oral antibiotics administrated the first day after a vaginal delivery with a second degree obstetric tear will decrease the risk of infection and/or wound dehiscence…
- Conditions
- Obstetric Trauma, Infections, Wound Dehiscence
- Trial name
- REPAIR (NCT05830162)
- Testing
- Bioclavid (Amoxicillin and Clavulanic acid)
- Where
- Denmark
- Volunteers
- 442 people
- Sponsor
- Hanna Jangö