Clinical trials: LGBTQ
Alcohol Use Disorder (AUD), PTSD
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
This is a two-part study to develop and test a brief, virtual therapy program for lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people who have experienced trauma and use alcohol.
- Trial name
- RISE (NCT07217795)
- Testing
- CBT + expressive writing, Wait-List Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Rhode Island
Minority Stress
Minority Stress Counseling for LGBTQ+ Individuals
Lesbian, gay, bisexual, transgender, and queer+ (LGBTQ+) individuals experience a breadth of mental health disparities. Reducing these disparities is an area of key psychological research.
- Trial name
- MST (NCT06614868)
- Testing
- Acceptance and Commitment Therapy, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sexual Minority Stress Experiences Among LGBTQ Youth
Feasibility of a Multi-Level School Intervention for LGBTQ Youth
The goal of this R21 grant is to test the feasibility of a theoretically informed, LGBTQ-affirming intervention (Proud \& Empowered; P\&E).
- Trial name
- NCT04041414
- Testing
- Proud & Empowered!
- Where
- 4 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Post-Traumatic Stress Disorder, Chronic, Depressed Mood
An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma
The researchers are testing a single-group cognitive-behavioral intervention for treating traumatic stress related to interpersonal and developmental trauma in LGBTQ adults.
- Conditions
- Post-Traumatic Stress Disorder, Chronic, Depressed Mood, Depressive and Anxiety Disorders, Anxiety
- Trial name
- NCT07863817
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Transgenderism, HIV Infections
Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions
The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and…
- Trial name
- NCT05666102
- Testing
- Transgender men's perspectives on HIV risk and HIV prevention interventions
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Bullying of Child
Evaluation of an Online Intervention to Help LGBTQ Youth Cope With Bullying
The purpose of this research study is to conduct a pilot randomized controlled trial of a game-based intervention is able to increase help-seeking-related knowledge, attitudes, and behaviors, reduce health risk factors/behaviors…
- Trial name
- NCT03501264
- Testing
- Online Game, LGBTQ Resources
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Pittsburgh
LGBTQ, Mental Health
A Self-compassion Intervention for LGBTQ+ Individuals
Gender and sexual minorities often face minority stress, leading to body dissatisfaction and potential psychological issues like anxiety and depression.
- Conditions
- LGBTQ, Mental Health, Body Image, Self-Compassion
- Trial name
- NCT06691282
- Testing
- Mindful self-compassion intervention
- Where
- Hong Kong
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Alcohol Drinking, Social Acceptance
PLANTS Pilot Trial
This pilot cluster-randomized controlled trial will evaluate the PLANTS (Providing LGBTQ+ Adolescents with Nurturance, Trustworthiness, and Safety) course among high school staff.
- Conditions
- Alcohol Drinking, Social Acceptance, Depressive Symptoms, Bullying
- Trial name
- PLANTS (NCT05897827)
- Testing
- PLANTS, EMAILS
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
LGBTQ
Assessing the Level of Awareness Regarding the Unique Medical Needs of the LGBTQ+ Community Among Emergency Department Physicians, as Well as Their Attitudes Toward Taking Medical Histories, Examining, and Treating Patients From This Community.
Assessing the level of knowledge and awareness regarding the unique medical needs of the LGBTQ+ community among emergency department physicians by distribution of questionnaires to all emergency department physicians (pediatric…
- Trial name
- NCT07770607
- Testing
- Distribution of Questionnaires
- Where
- 3 sites in Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Sexual Harassment, Anti-Gay Bias
Effectiveness Study of the Intervention "Stop Sexual Harassment" in Secondary School
"Stop sexual harassment" is a school based intervention tailored to reduce sexual- and gendered harassment among pupils in secondary school.
- Conditions
- Sexual Harassment, Anti-Gay Bias, Non Sexual Harassment, Gender-based Violence
- Trial name
- NCT04716400
- Testing
- Stop sexual harassment
- Where
- Norway
- Volunteers
- 2,037 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS
Smoking Cessation
SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups
The purpose of this study is to test the feasibility and acceptability of Smokefree Sexual and Gender Minority (SGM), an SGM-tailored version of the SmokefreeTXT text messaging program
- Trial name
- NCT05645354
- Testing
- SmokefreeSGM, SmokefreeTXT
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Parkinson Disease, Sexual Orientation
Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+
Study Rationale: Older adults who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have worse health than non-LGBTQ+ older adults.
- Trial name
- LGBTQ+_PD (NCT05502055)
- Testing
- Individual interviews, Focus Groups, National Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Creighton University
LGBTQ, Sexual Behavior
A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
This study is to test the efficacy of an online CBT intervention (EQuIP) that addresses the pathways through which minority stress compromises LGBTQ young adults' co-occurring mental (e.g., depression) and behavioral (e.g.…
- Trial name
- NCT04408469
- Testing
- Online EQuIP, Self-monitoring control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
HIV/STI Incidence, Communication About Health Information
The Gender Inclusive Sexuality Talks Program
The study is centered on helping parents answer and meet the sexuality-specific questions and needs of transgender, gender diverse, lesbian or bisexual female youth.
- Trial name
- GIST (NCT07825571)
- Testing
- The Gender Inclusive Sexuality Talks Program, GIST Control
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
LGBTQ, Sexual Behavior
Developing Online Interventions to Reduce Stigma-Related Stress, Sexual Health, and HIV Risk Among Young Chinese MSM
This study is a 2-arm RCT that will assess the efficacy of a culturally adapted, 10-session SGM-affirmative, internet-based cognitive behavioral therapy (iCBT) among young men who have sex with men (YMSM) in Hunan province China.
- Conditions
- LGBTQ, Sexual Behavior, HIV Risk
- Trial name
- NCT04718194
- Testing
- ESTEEM iCBT, Self-monitoring control
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity & Overweight
A Single-arm Pilot Feasibility Trial of Healthy Pride
This is a one-arm pilot trial of a 12-week digitally-delivered asynchronous lifestyle intervention designed for gay men and lesbian women.
- Trial name
- NCT07690592
- Testing
- lifestyle intervention
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Anxiety Disorders, Depression
LGBTQ-affirmative CBT for Youth
This study will adapt LGBTQ-affirmative cognitive behavior therapy (CBT) - previously only used with adults - for youth aged 12-17 years.
- Conditions
- Anxiety Disorders, Depression, LGBTQ
- Trial name
- NCT05408858
- Testing
- LGBTQ-affirmative cognitive behavioral group therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stigma, Social
TENNacity Trial: A Pilot Test of Intersectional CBT Among Young Southern Black and Latino/x GBQ+ Men
This open pilot involves testing the acceptability and feasibility of an intersectional, culturally responsive health intervention by piloting it among young Black and Latino/x gay, bisexual, and queer (GBQ+) men residing in…
- Trial name
- NCT07793357
- Testing
- Adapted ESTEEM intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University