Clinical trials: Knee Pain Arthritis
Osteoarthritis, Knee
The Effect of Therapeutic Methods for Chronic Knee Osteoarthritis Pain
Chronic osteoarthritis (OA) pain of the knee is not effectively abrogated by the available non-pharmacologic or pharmacologic treatments. Radiofrequency (RF) neurotomy is a therapeutic alternative for chronic pain.
- Trial name
- NCT00924677
- Testing
- radiofrequency neurotomy for genicular nerve
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Osteoathritis
Medial-Wedge Insole is Highly Effective in the Treatment of Valgus Knee Osteoarthritis
To assess the efficacy of medial-wedge insole in valgus knee osteoarthritis (OA). We hypothesized that medial-wedged insoles are biomechanically effective and should reduce lateral compartment loading in persons with valgus knee…
- Trial name
- NCT00467337
- Testing
- Medial-Wedge Insole intervention
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteo Arthritis Knee, Pain, Chronic
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Inflammation
- Trial name
- NCT03924128
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteoarthritis of the Knee
Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management
Three primary reasons prolong hospital stays following unilateral knee arthroplasty. Pain is the primary reason followed by opioid drowsiness and nausea/vomiting side effects.
- Trial name
- RFA (NCT02925442)
- Testing
- t-RFA, C-RFA, Control
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lyman Medical Research Foundation, Inc.
Knee Osteoarthritis, Knee Pain Chronic
The Effect of PEMF for Patients With Knee OA
Health care costs are increasing alarmingly, which will impose an overwhelming economic burden to an aging society like that of Hong Kong.
- Trial name
- NCT05548712
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis
An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis
This is a Prospective, Randomized study evaluating the efficacy of ReNu for the treatment of Kellgren-Lawrence grade 2 or 3 osteoarthritis.
- Trial name
- NCT02318511
- Testing
- Knee injection, ReNu amniotic allograft, Hyaluronic Acid
- Where
- 12 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NuTech Medical, Inc
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Knee Arthritis
The Efficacy of Collaborative Patient Education on Total Knee Arthroplasty
This project is about the integrated rehabilitation program for the patients receiving total knee arthroplasty. The investigators are monitoring the WOMAC(Western Ontario and Mcmaster University Arthritis Index)/ Pain…
- Trial name
- NCT05346822
- Testing
- integrated rehabilitation (the collaborative patient education)
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Osteoarthritis
A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain
Osteoarthritis is a degenerative joint disease and is the most common form of arthritis. This study will evaluate the effectiveness of customized shoe inserts in controlling and relieving the pain of knee osteoarthritis.
- Trial name
- NCT00076453
- Testing
- Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthritis (Knee OA)
Cross-linked Hyaluronic Acid in Knee Osteoarthritis
Knee Osteoarthritis (Knee OA) leads to pain and loss of function, especially in recreational athletes. While hyaluronic acid (HA) injections are a common part of conservative treatment, comparative data on the efficacy of…
- Trial name
- NCT07241442
- Testing
- Straight-bonded hyaluronic acid, cross-linked hyaluronic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Knee Osteoarthritis
Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
Intraarticular injection (IAI) of Platelet rich plasma (PRP) with Hyaluronic acid (HA) Versus Radiofrequency (RF) of genicular nerve for pain reduction of of knee osteoarthritis , Improving daily activity and reduction analgesia…
- Trial name
- NCT04188561
- Testing
- Intra articular injection Group, Radiofrequency Group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arthritis Knee
Heat Application to Quadriceps Effect on Pain After a Total Knee Arthroplasty
The goal of this study is to explore an under-researched aspect of recovery. Typically, post-operative care after a knee arthroplasty consists of compression (stockings), medications, rest, ice, elevation, physical therapy, and…
- Trial name
- NCT05462483
- Testing
- Rice Sock and Instructions to heat the quadriceps.
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- The Idaho Clinic
Osteoarthritis, Knee, Pain
Pain Phenotypes in Knee Osteoarthritis
Recently, the medical community has learned damage to the knee joint may be one of many possible reasons for pain in knee osteoarthritis.
- Trial name
- NCT02664896
- Testing
- Knee Osteoarthritis, Healthy Control
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Knee Osteoarthritis
Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain
This purpose of this study is to evaluate the effectiveness and safety of the iovera° device for the temporary reduction of pain associated with knee osteoarthritis.
- Trial name
- NCT02260921
- Testing
- iovera°
- Where
- 17 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis, Knee
A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee
This multicenter, randomized, double-blind study will be performed in approximately 600 subjects with chronic idiopathic osteoarthritis (OA) of the knee. An open-label safety extension will follow.
- Trial name
- NCT00379236
- Testing
- EUFLEXXA™
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Osteoarthritis, Knee
A Comparison Between GLA:D Canada and an Individualized JointEffort Exercise Program in Knee Osteoarthritis Patients
Osteoarthritis (OA) is the leading cause of disability worldwide and affects more than 4.4 million people in Canada (13% of Canadians).
- Trial name
- NCT03406767
- Testing
- GLA:D Canada Program, JointEffort Program
- Where
- 4 sites in Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Knee Osteoarthritis, Blood Loss
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Trial name
- NCT05099276
- Testing
- Tranexamic Acid Pill
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Osteoarthritis of the Knee
Knee Osteoarthritis Risk in Retired Professional Footballers
The OA and Football Study is an epidemiological study designed to establish the prevalence of knee osteoarthritis in retired professional footballers.
- Trial name
- NCT02098044
- Where
- United Kingdom
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic