Clinical trials: Kidney Disease, Chronic
End-stage Renal Disease, Malnutrition; Protein
Impact of IDPN on Nutrition Markers in Patients Receiving ICHD
Evaluate the impact of intradialytic parenteral nutrition (IDPN) compounded with Clinisol, Prosol, and/or Clinolipid on albumin levels and weight in patients with end-stage renal disease (ESRD) undergoing in-center hemodialysis.
- Trial name
- NCT05439174
- Testing
- Intradialytic Parenteral Nutrition
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Patient Care America
Acute Kidney Injury, Renal Insufficiency,Chronic
Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial
This study is testing whether finerenone, when compared to placebo, is a tolerable and safe intervention when administered in patients with acute kidney injury (AKI).
- Conditions
- Acute Kidney Injury, Renal Insufficiency,Chronic, Kidney Diseases
- Trial name
- FiPAKI (NCT07775482)
- Testing
- Finerenone (BAY94-8862 ) 10 mg
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Jean-Maxime Côté
ESRD, T-Cell Dysfunction
T Cell Dysfunction in ESRD
Patients with end-stage renal disease (ESRD) suffer from high morbidity and mortality of cardiovascular and infectious disease and increased risk of all-cause mortality which is mainly attributed to the disturbed immune response.
- Trial name
- NCT04658069
- Testing
- no specific interventions
- Volunteers
- 400 people
- Sponsor
- Shanghai Zhongshan Hospital
Chronic Kidney Disease, Cardiovascular Disease
Mechanisms of Chronic Kidney Disease (CKD)-Induced Foam Cell Formation
There is currently little understanding of macrophage cholesterol homeostasis and foam cell formation across the spectrum of CKD.
- Trial name
- NCT01671605
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Diseases
Renasight Clinical Application, Review and Evaluation (RenaCARE) Study
This study is an open-label, multi-center study evaluating the clinical utility of Renasight in the diagnosis and management of kidney disease.
- Trial name
- RenaCARE (NCT05846113)
- Testing
- Renasight
- Where
- 31 sites in United States
- Volunteers
- 1,720 people
- Sponsor
- Natera, Inc.
End Stage Renal Disease
Prognostic Value of Central and BracHial Ambulatory Blood Pressure Monitoring in ERSD Patients Treated With HeMOdialysis
This is a prospective cohort study which aims to explore the significance of brachial and central ambulatory blood pressure monitoring in predicting cardiovascular risk in patients with end stage renal disease who are treated…
- Trial name
- C-HEMO (NCT03306160)
- Testing
- 48-hour blood pressure ambulatory monitoring
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Shanghai 10th People's Hospital
Renal Disease, Chronic, Renal Disease, End-Stage
Non-invasive Testing for End-Stage Chronic Kidney Disease
This study evaluates the clinical performance of a non-invasive digital diagnostic test (KF4+, developed and manufactured by Gisens Biotech) for the measurement of urea and potassium in capillary blood in patients with end-stage…
- Conditions
- Renal Disease, Chronic, Renal Disease, End-Stage, Dialysis Patients, Urea in Blood; High
- Trial name
- NiTED (NCT07777523)
- Testing
- KF4+ Noninvasive Test
- Where
- Argentina
- Volunteers
- 55 people
- Sponsor
- Gisens Biotech
Infection, Heart Failure
Rural Home Hospital: Proof of Concept
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04531280
- Testing
- Home hospital care
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brigham and Women's Hospital
Chronic Renal Failure
Physical Activity in Dialysis: Clinical and Biological Impact
Physical inactivity is known to increase the risk of developing many diseases as cardiovascular diseases, diabetes, some cancers, and other chronic diseases.
- Trial name
- NCT04525196
- Testing
- Physical activity.
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Elsan
Graft Failure, Dialysis
Factors for Impairment of Renal Graft Function in Intensive Care
hypothesis = hospitalization in the intensive care unit (ICU) has an impact on the outcome of the renal graft, due to the therapeutic and exploratory procedures performed.
- Conditions
- Graft Failure, Dialysis, Chronic Kidney Failure
- Trial name
- RENAGRAF (NCT06191146)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
End Stage Renal Disease
Study the Effect of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Level in Hemodialysis Patients
The goal of this clinical trial is to learn if probiotic has an effect on Trimethylamine-N-Oxide Plasma Level in plasma, which represent strong risk factor for Atherosclerosis in end stage renal disease patients who undergoing…
- Trial name
- probiotic (NCT06421883)
- Testing
- Lactobacillus containing probiotic
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Chronic Allograft Nephropathy
Effects of PGI2 Analogue Use on the Development of Chronic Allograft Nephropathy
The purpose of this study is to evaluate the effect of Prostaglandin I2 analogue use on the development of chronic allograft nephropathy and changes in allograft function in prevalent renal transplant recipients
- Trial name
- NCT01056835
- Testing
- prostaglandin I2 analogue
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
End Stage Renal Disease (ESRD), End Stage Kidney Disease (ESRD)
Effect of a Plant-Focused Diet on Nutritional Status in Malnourished Peritoneal Dialysis Patients
The goal of this clinical trial is to determine whether a plant-focused diet improves nutritional and health outcomes of malnourished adults undergoing peritoneal dialysis (PD).
- Conditions
- End Stage Renal Disease (ESRD), End Stage Kidney Disease (ESRD), Peritoneal Dialysis (PD), Malnourished
- Trial name
- NCT07157397
- Testing
- Plant-Focused Diet Counselling, Standard Renal Diet Counselling
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- National University of Malaysia
Fabry Disease, Chronic Kidney Disease, Stage IV (Severe)
Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme
This study was designed to determine appropriate treatment with Fabrazyme at a biweekly dose of either 1 mg/kg or 3 mg/kg in a population of patients with severe renal disease burden.
- Trial name
- NCT00837824
- Testing
- Fabrazyme (agalsidase beta)
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- Genzyme, a Sanofi Company
Infections, Heart Failure
Rural Hospital-Level Care at Home for Acutely Ill Adults
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infections, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05256303
- Testing
- Home Hospital care, Traditional Hospital care
- Where
- 3 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
Peritoneal Dialysis Complication, Hypoalbuminemia
The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
This study is a prospective open label clinical trial comparing serum albumin levels and total protein intake in the peritoneal dialysis patient population.
- Conditions
- Peritoneal Dialysis Complication, Hypoalbuminemia, Malnutrition
- Trial name
- NCT03569410
- Testing
- increased protein intake via natural foods, increase protein intake via protein supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Renal Insufficiency, Chronic, Kidney Disease, Chronic
A Study of LY2928057 in Hemodialysis Participants
This study will evaluate the safety of LY2928057 and how LY2928057 affects hemoglobin in hemodialysis participants. This study will involve multiple doses of LY2928057 given during a 6 week period either after a participant…
- Trial name
- NCT01991483
- Testing
- LY2928057
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- Eli Lilly and Company
End Stage Renal Disease
Pharmacokinetics of Immunosuppressants in Renal Transplant Candidates Who Have Undergone Laparoscopic Sleeve Gastrectomy
The purpose of this study is to evaluate how quickly and to what extent different immunosuppressants are absorbed into the blood (this is called pharmacokinetics) in renal transplant candidates who have undergone a laparoscopic…
- Trial name
- NCT02221583
- Testing
- Astagraf XL, Prograf, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Cincinnati
Chronic Kidney Disease (Mild to Moderate)
Effect of Resistance Exercises and Relaxation Therapy on Physical Function and Quality Of Life in Patients With Chronic Kidney Disease
The significance of this study to compare the effect of resistance exercises and relaxation therapy to find out which technique is more effective for improving physical function and quality of life in chronic kidney disease…
- Trial name
- NCT07370662
- Testing
- Resistance exercises:, Relaxation exercise
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rashid Latif Medical College
Chronic Kidney Disease Stage 3 and 4, Diabetes
Prediction of Peripheral Neuropathy With Functional Testing
Diabetes and chronic kidney disease (CKD) are two distinct pathologies. The former is defined as an impairment in insulin production and/or utilization, while the latter refers to structural or functional abnormalities of the…
- Trial name
- PredictNP (NCT06933108)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Université catholique de l'Ouest
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