Clinical trials: Joint Contractures
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Dupuytren Contracture
BOND Study: the Benefit Of Night Splinting in Dupuytrens'
The BOND study is a prospective, randomised single blinded controlled trial to assess the effect of night splinting in patients who have had collagenase injection and manipulation therapy for Dupuytren's Contracture.
- Trial name
- BOND (NCT03031080)
- Testing
- Thermoplastic Hand Splint
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Dupuytren's Disease
Retreatment of Recurrent Dupuytren's Contractures
The objectives of this study are to assess the safety and efficacy of AA4500 in the retreatment of recurrent contractures in joints that were effectively treated with AA4500 in a previous Auxilium-sponsored Phase 3 study.
- Trial name
- NCT01498640
- Testing
- Collagenase clostridium histolyticum
- Where
- 13 sites in United States, Australia and 2 more
- Volunteers
- 52 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Dupuytren's Contracture
Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures
The primary objective of this study is to assess the safety of two concurrent injections of AA4500 into the same hand in subjects with multiple Dupuytren's contractures with palpable cords followed 24 to 72 hours later by a…
- Trial name
- NCT01674634
- Testing
- XIAFLEX / XIAPEX
- Where
- 25 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Hip Joint Contracture
Sonographic Study of Hip Joint in Hockey Players
The aim is to determine whether the game of ice hockey has an effect on structural changes in the hip joint. The parameter to be investigated will be the increased frequency of structural changes of the hip joint in ice hockey…
- Trial name
- NCT05788419
- Testing
- sonography
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Burn Joints, Joint Contractures
Effect of Paraffin Wax on Joint Contractures
Limited studies have objectively evaluated the benefit on skin pliability, and relieving itch and pain of paraffin wax, nor has paraffin wax treatment been compared to mineral oil, which is an ingredient in therapeutic paraffin…
- Trial name
- NCT07837687
- Testing
- Paraffin wax, Mineral oil
- Volunteers
- 12 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Contracture of Elbow Joint
Immediate Effects of Superficial Heat Associated With Elongation in the Posttraumatic Elbow Contracture
The elbow contracture is a secondary injury that can occur after direct trauma, causing the patient to have limitations in their range of motion.
- Trial name
- NCT03179098
- Testing
- Modified Weeks protocol, CIVM, GC- Sustained Stretching
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Ankle Joint Contracture
Effect of Mobilization With Movement on Weight Bearing Ankle Dorsiflexion Range of Motion
Limited ankle range of motion is associated with increased risk for ankle sprains, knee joint dysfunction and injury to the ACL.
- Trial name
- NCT05844072
- Testing
- Mobilization with movement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Dupuytren's Contracture
Phase II Randomized Study of Collagenase in Patients With Residual Type Dupuytren's Disease
OBJECTIVES: Evaluate the safety and efficacy of collagenase in improving flexion deformity, range of motion, and grip strength in patients with residual Dupuytren's disease.
- Trial name
- NCT00004409
- Testing
- collagenase
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- State University of New York
Shoulder Impingement, Shoulder Pain
Comparison of Pragmatic Posterior Capsular Stretch and Crossbody Stretch on the Shoulder Mobility
Various stretches are used to lengthen the posterior shoulder capsule. No study has reported the comparison of the pragmatic posterior capsular stretch and cross body stertch
- Conditions
- Shoulder Impingement, Shoulder Pain, Adhesive Capsulitis, Rotator Cuff Tears
- Trial name
- NCT04692649
- Testing
- pragmatic posterior capsular stretch, cross body stretch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Ankle Joint Contracture, Knee Injuries and Disorders
Immediate Effects of Two Ankle Mobilization Techniques in the Amplitude of Dorsiflexion and Dynamic Valgus Knee
Dynamic knee valgus is an inadequate biomechanical movement of multifactorial cause that may expose the individual to various injuries. The range of motion of ankle dorsiflexion is one of the possible influencing factors.
- Trial name
- NCT03171233
- Testing
- Mobilization with movement, Self mobilization with movement
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Shoulder Impingement, Shoulder Pain
Comparison of Shoulder Stretches
Various stretches are used to lengthen the posterior shoulder capsule. No study has reported the comparison of the pragmatic posterior capsular stretch and cross body stertch
- Conditions
- Shoulder Impingement, Shoulder Pain, Adhesive Capsulitis, Rotator Cuff Tears
- Trial name
- NCT05324722
- Testing
- pragmatic posterior capsular stretch, cross body stretch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Skin Laxity, Muscle Contracture
Evaluation of the Immediate Effect and Safety of DMA™ Novel Muscle Stimulation Technology
A total of at least 15 and up to 17 healthy subjects at a single site, aged 25-45 years old, who wish to receive a lifting effect and improved muscle definition, will be included in the study.
- Trial name
- NCT04296201
- Testing
- DMA treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Contractures, Scars
Preexpanded Perforator Flaps in Children
Contractures and broad scars of the axilla, anterior chest wall and neck have detrimental effects on functional, physical and psychological development of children.
- Trial name
- NCT01700595
- Testing
- new technical intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Istanbul University
Finger Proximal Interphalangeal Joint Contracture
A Novel Shape Memory Alloy-Based Orthosis for Proximal Interphalangeal Joint Stiffness
The goal of this clinical trial is to evaluate the applicability, effectiveness, and usability of a shape memory alloy-based orthosis for patients with finger proximal interphalangeal joint stiffness.
- Trial name
- NCT06716086
- Testing
- shape memory alloy-based orthosis, conventional stretching program
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Elbow Fracture, Joint Contracture
Synovial Fluid Analysis of Intraarticular Elbow Fracture
The objective of this study is to obtain and compare bilateral elbow joint synovial fluid from patients with unilateral intraarticular elbow fracture and a contralateral healthy appearing elbow joint.
- Trial name
- NCT02878941
- Testing
- Synovial Fluid Analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Knee Osteoarthritis, Arthroplasty
An Attempt to Find Out Root Cause of a Pain Producing Knee Disease
This study was focused on a type of arthritis (knee) in which patients develop pain with disabilities in sitting and walking etc. In advance stage the person is bereft of his/her personal physical activities.
- Conditions
- Knee Osteoarthritis, Arthroplasty, Knee
- Trial name
- NCT04496440
- Testing
- Contracture Correction Therapy
- Where
- 6 sites in India
- Volunteers
- 138 people
- Sponsor
- DR R C Agrawal
Breast Cancer, Yoga Therapy
The Effect of Yoga Therapy on Post-operative Side-effects Among Women With Breast Cancer
The present study evaluates the effect of yoga therapy on scarring contractures and shoulder joint motion and range in women diagnosed with breast cancer. A single-blinded prospective, randomized controlled trial will be used.
- Conditions
- Breast Cancer, Yoga Therapy, Shoulder Joint Motion, Scar Contracture
- Trial name
- NCT05820373
- Testing
- Yoga therapy, Active control group, Passive control group
- Volunteers
- 444 people
- Sponsor
- The University of Hong Kong