Clinical trials: Intubation, Endotracheal
Mechanical Ventilation Complication, Tracheal Intubation Morbidity
Continuous Control of Polyurethane Tracheal-cuff Pressure: Efficiency of a Pneumatic Device
Underinflation and overinflation of tracheal cuff are common in intubated patients, including those intubated with polyurethane-cuffed tubes.
- Trial name
- Nosten (NCT01351259)
- Testing
- Pneumatic device, cylindrical or tapered cuff
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Lille
Pressor Response
Dexmedetomidine for Attenuation of Pressor Response
Direct laryngoscopy and tracheal intubation are usually associated by hemodynamic changes due to increased sympathoadrenal activity which could precipitate serious negative effects in compromised patients .
- Trial name
- Precedex (NCT06592027)
- Testing
- PRECEDEX INJ★ 2ML
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Theodor Bilharz Research Institute
General Surgery
Comparison of Apnea Tolerance in Two Positions of Patients With BMI 30-40
The purpose of this study is to compare the effect of the 25° head-up position versus the 55° head-up position on tolerable apnea time (TAT) after induction of general anesthesia in patients with a body mass index (BMI) of 30-40.
- Trial name
- NCT03056820
- Testing
- 25° head-up position, 55° head-up position
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas Medical Center
Sedation Complication
Application of Dexmedetomidine Hydrochloride Injection in Anesthesia for Patients Without Tracheal Intubation
With 0.9% sodium chloride injection as a placebo control, to evaluate the effectiveness and safety of dexmedetomidine hydrochloride injection for sedation in patients with non-tracheal intubation
- Trial name
- NCT04652427
- Testing
- Dexmedetomidine Hydrochloride 0.1 MG/ML, 0.9% Sodium Chloride Injection
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University People's Hospital
Intubation
LarynGuide™ Assisted Tracheal Intubation
This study aims to asses if the application of the larynGuide™, an assistive software running on a video-laryngoscope platform guiding laryngoscopy and intubation advise correctly and reliably on the position of the tracheal tube…
- Trial name
- LarynGuide (NCT06397261)
- Testing
- LarynGuide
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypoxia, Hypoventilation
Spirometric Detection of Esophageal Intubation
In endotracheal intubation, it is essential that the trachea is intubated and not the esophagus. In suboptimal situations (outside an operating theatre), malpositioning of the endotracheal tube occurs frequently and is often…
- Trial name
- NCT02052869
- Testing
- esophagus intubation
- Where
- Netherlands
- Sponsor
- University Medical Center Groningen
Intubation Complication
Comparison of the Intubation Condition Between Two Different Types of Video Laryngoscope Blades
The present study compares two different types of videolaryngoscope blade, which is a channeled and non-channeled blade. The purpose of the study is to investigate the effect of the type of videolaryngoscope blade on the…
- Trial name
- NCT04948294
- Testing
- Channeled blade, Non-channeled blade
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Lung Neoplasms
Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine
The goal of this clinical trial is to test the effect of nebulized lidocaine on the hemodynamic response in the participant undergoing double-lumen endotracheal intubation.
- Trial name
- NCT05850702
- Testing
- Lidocaine, Saline
- Volunteers
- 92 people
- Sponsor
- RenJi Hospital
Mechanical Ventilation Complication
Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition
In this study, the investigators adopt the special endotracheal tube to those patients at prone posture during the operation,or those with acute respiratory distress syndrome in the intensive care unit(ICU), so that the…
- Trial name
- NCT02449356
- Testing
- prone position endotracheal tube(PPT)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wangyuan Zou
Intubation; Difficult or Failed
Video Laryngoscope Versus USB Borescope in Difficult Intubation
Video Laryngoscope Versus a USB Borescope Aided Endotracheal Intubation in Adults With Anticipated Difficult Airway
- Trial name
- NCT05158088
- Testing
- Borescope, Video laryngoscope
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intubation Skill, Intubation Complications
Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.
When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe.
- Conditions
- Intubation Skill, Intubation Complications, Intubation With Uncuffed Endotracheal Tube
- Trial name
- NCT07600502
- Testing
- Hyperangulated videolaryngoscopy
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Intubation Complication
Nasal Intubation：a Comparison of Different Endotracheal Tubes
Either uses two different endotracheal tubes to pass the nasal cavity and to compare the effects on the secretion and bleeding volume of patients during intubation to facilitate nasotracheal tube advancement.
- Trial name
- NCT05112783
- Testing
- Henan Tuoren Endotracheal Tube, Smiths Portex Tracheal Tubes
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Intubation, Intratracheal
Learning Curve of Optiscope by Anesthesia Providers
Optiscope (Clarus Medical, Minneapolis, MN, USA) is a semi-rigid fiberscope for endotracheal intubation. This study will investigate learning curve of Optiscope by anesthesia providers.
- Trial name
- NCT01974505
- Testing
- intubation using optiscope
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Jeju National University School of Medicine
Trauma, Patient Satisfaction
Awake Endotracheal Intubation in Cervical Injury
The researcher will compare awake endotracheal intubation with glidescope video assisted laryngoscope vs fiberoptic bronchoscope in patients with traumatic cervical injury;
- Conditions
- Trauma, Patient Satisfaction, Airway Morbidity
- Trial name
- NCT05619965
- Testing
- sedative, Awake endotracheal intubation by Glidescope videolaryngoscope, Awake endotracheal intubation by Fiberoptic bronchoscope
- Volunteers
- 100 people
- Sponsor
- Tanta University
Orotracheal Intubation
Stylet Use for McGrath Videolaryngoscope
The routine use of a styletted endotracheal tube during videolaryngoscopy is advocated by some manufacturers, but styletted endotracheal tube can elicit rare but potentially serious complications.
- Trial name
- NCT02642367
- Testing
- McGrath videolaryngoscope, McGrath videolaryngoscope with Intubating stylet (Mallinckrodt), rocuronium
- Where
- 2 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Ajou University School of Medicine
Medical Device, Medical Device Performance
Clinical Evaluation of an Airborne Pathogen Containment Device: Randomized Open-label Equivalence Trial During Endotracheal Intubation
The aim of this study is to test a bubble-like dome (made of clear plastic) being placed over patients' heads during surgery as a tool to prevent the spread of germs through the air in hospitals.
- Conditions
- Medical Device, Medical Device Performance, Aerosol Generating Procedure
- Trial name
- NCT06968377
- Testing
- A novel airborne pathogen containment device.
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Endotracheal Intubation, Continuous IV Sedation
Cerebral Perfusion Pressure Using Precedex and Other Sedatives
The purpose of this study is to examine the effects of using dexmedetomidine (Precedex) in addition to the current standard-of-care for sedation.
- Conditions
- Endotracheal Intubation, Continuous IV Sedation, ICP Monitoring
- Trial name
- C3PO (NCT01169467)
- Testing
- Standard-of-Care plus Dexmedetomidine, Standard-of-Care
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Duke University
COVID-19 Acute Respiratory Distress Syndrome
Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients
In this comparative prospective study, we aim to compare the classic Macintosh laryngoscope and the Mac Grath videolaryncoscope in ICU covid 19 patients recruiting intubation and invasive mechanical ventilation.
- Trial name
- NCT04956913
- Testing
- Mac Grath, Macintosh
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Laryngoscopy, Intubation
Comparison Study in Adult Surgical Patients of 5 Airway Devices
The placement of endotracheal tubes (intubation) is a physiologically stressful procedure for patients. Laryngoscopes are devices-typically composed of a blade attached to a handle with a light source-that allow examination of…
- Trial name
- NCT00602979
- Testing
- Macintosh laryngoscope, Airtraq® Optical Laryngoscope, Storz DCI Video Laryngoscope®
- Volunteers
- 240 people
- Sponsor
- Weill Medical College of Cornell University
Mechanical Ventilation, Nonverbal Communication
Brain Computer Interface for Communication in Ventilated Patients
Objectives: Specific Aim 1: To demonstrate the feasibility of using a Steady State Visual Evoked Potential (SSVEP) based Brain Computer Interface (BCI) device to facilitate communication of common patient needs in alert…
- Conditions
- Mechanical Ventilation, Nonverbal Communication, Intratracheal Intubation, Critical Illness
- Trial name
- NCT02791425
- Testing
- Brain Computer Interface (BCI) device, Communication picture board
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan