Clinical trials: Intraocular Pressure, open to volunteers
Intraocular Pressure (IOP), Healthy Adult
Eplerenone and IOP in Healthy Adults
The goal of this clinical trial is to determine whether eplerenone lowers eye pressure in healthy adults. Eplerenone is a medication approved by the U.S. Food and Drug Administration for other medical conditions.
- Trial name
- NCT07795762
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Direct vs Standard SLT for Glaucoma: A Noninferiority Trial
This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss.
- Trial name
- NCT07408154
- Testing
- Direct Selective laser Trabeculoplasty
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Medical University of South Carolina
Glaucoma, Open Angle, MIGS
Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty
The goal of this study is to learn if combining minimally invasive glaucoma surgery (MIGS) procedures with different mechanisms of action increases the effectiveness of MIGS.
- Conditions
- Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty
- Trial name
- NCT07073937
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Pseudophakic Bullous Keratopathy, Fuchs' Endothelial Dystrophy
The OPTIMISE Study
Rationale: The cornea is the most transplanted tissue in the Netherlands, with more than 1,500 procedures performed each year. A minimally invasive technique called Descemet Membrane Endothelial Keratoplasty (DMEK) has become the…
- Conditions
- Pseudophakic Bullous Keratopathy, Fuchs' Endothelial Dystrophy, Intraocular Pressure
- Trial name
- NCT05716945
- Testing
- Fluorometholone 0.1% Oph Susp, Dexamethasone 0.1% ophthalmic suspension, Stop steroids
- Where
- 8 sites in Netherlands
- Volunteers
- 342 people
- Sponsor
- Maastricht University Medical Center
Glaucoma
Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years
The purpose of this study is to evaluate the long-term effectiveness and safety of the Hydrus implant combined with concomitant phacoemulsification for lowering intraocular pressure (IOP).Glaucoma patients often have high…
- Trial name
- NCT07460791
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Johannes Gutenberg University Mainz
Glaucoma
The Effectiveness Of Home-Based Circuit Training On Eye Pressure And Eye Nerve Structures In Patients With Glaucoma
The goal of this randomised control trial is to learn about the effect of home based circuit training on patients with primary glaucoma. The main questions to answer are: 1.
- Trial name
- NCT07733388
- Testing
- Home-Based Circuit Training
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Intraocular Pressure
Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries
The aim of this study is to examine the effects of intraoperative systemic use of dexmedetomidine on the intraocular pressure (IOP) in patients undergoing spine surgeries in a prone position under general anesthesia.
- Trial name
- NCT04628663
- Testing
- Dexmedetomidine, Normal Saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Primary Open Angle Glaucoma, Glaucoma
A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
Background Glaucoma is a progressive optic neuropathy characterized by elevated intraocular pressure (IOP), leading to irreversible vision loss.
- Conditions
- Primary Open Angle Glaucoma, Glaucoma, Primary Open Angle Glaucoma or Ocular Hypertension
- Trial name
- NCT07076303
- Testing
- Direct Selective Laser Trabuloplasty
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brian Shafer
Glaucoma
Glaucoma Laser Assessment of Stability and Sustainability
The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or…
- Trial name
- GLASS (NCT06963684)
- Testing
- Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Twin Cities Eye Consultants
Pediatric Sleep Disordered Breathing, Obstructive Sleep Apnea
Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study
The goal of this clinical trial is to learn whether a newer sleep-testing device gives results that closely match the standard overnight sleep study, in children and adolescents ages 6-18 who are being evaluated for possible…
- Trial name
- NCT07851402
- Testing
- WatchPAT 400
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Milton S. Hershey Medical Center
Primary Open Angle Glaucoma (POAG)
Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Eye Pressure in Non-Caucasian Patients With Open Angle Glaucoma
The goal of this clinical trial is to to evaluate how well Direct Selective Laser Trabeculoplasty (DSLT) lowers eye pressure in eyes of adult, non-Caucasian participants with primary open angle glaucoma.
- Trial name
- NCT07147647
- Testing
- Direct Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Select Eye Care
Ocular Hypertension Glaucoma, POAG
Direct Selective Laser Trabeculoplasty (DSLT) for Patients With Glaucoma or Ocular Hypertension Previously Treated With SLT
This study looks at a new laser treatment for people with high eye pressure or a type of glaucoma called open-angle glaucoma. All patients in the study have already had a similar laser treatment before (called SLT).
- Trial name
- NCT07589270
- Testing
- DSLT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The New York Eye Surgery Center
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCT
This study compares two laser treatments for open-angle glaucoma: Selective Laser Trabeculoplasty (SLT) and Direct Selective Laser Trabeculoplasty (DSLT).
- Trial name
- NCT06925477
- Testing
- DSLT treatment for Open-Angle Glaucoma, SLT treatment for Open-Angle Glaucoma
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical University of South Carolina
Pars Plana Vitrectomy
INTRAOCULAR PRESSURE MEASUREMENT AT the END of PARS PLANA VITRECTOMY
Intraocular pressure is measured regularly at any and all visits with your eye doctor or optometrist. The purpose of this study is to compare measurements of eye pressure at the end of the surgery, comparing the ability of a…
- Trial name
- NCT06707168
- Testing
- Digital palpation, Cotton-tipped applicator (CTA)
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Intraocular Pressure, Refractive Surgery
Measuring the Changes of the Intraocular Pressure After Corneal Laser Refractive Surgery Using Different Techniques
To evaluate the changes that occur in the intraocular pressure after corneal refractive surgery either PRK , LASIK and femtosecond laser by using Corvis CT results and applanation tonometer
- Trial name
- NCT07549815
- Testing
- Corvis machine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Keratoconus, Intraocular Pressure
Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT
To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.
- Trial name
- NCT07599020
- Testing
- Corvis Machine
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cataract, Glaucoma
Low Intraocular Pressure Cataract Surgery With Zeiss Quatera in Glaucoma Patients
You were selected to participate in this observational study because you suffer from glaucoma and cataracts. For the cataract you will have cataract surgery.
- Trial name
- NCT06712758
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Visionair Oogzorg
Glaucoma
Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery
The goal of this clinical trial is to determine if the intraoperative application of Mitomycin-C can enhance the outcomes of Ahmed Glaucoma Valve (AGV) implantation in treating refractory glaucoma.
- Trial name
- MMC (NCT06680245)
- Testing
- Mitomycin c
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Healthy Participants
The Effects of Strength Training Volume, Intensity, and Breathing Techniques on Intraocular Pressure and Retinal Blood Vessels
This study aims to determine the effects of different breathing patterns on ocular vasculature and intraocular pressure (IOP) during isokinetic and isometric strength exercises.
- Trial name
- NCT07326462
- Testing
- Normal Breathing, Valsalva maneuver
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Primary Open Angle Glaucoma or Ocular Hypertension
A Comparative Study of Intraocular Pressure Control Using Selective Laser Trabeculoplasty and Latanoprost as Initial Treatments for Primary Open Angle Glaucoma and Ocular Hypertension in Lagos State University Teaching Hospital
The goal of this clinical trial is to compare the short-term efficacy and safety of selective laser trabeculoplasty (SLT) to 0.005% latanoprost eye drops in lowering intraocular pressure (IOP) as primary therapy in…
- Trial name
- NCT07310719
- Testing
- Selective laser trabeculoplasty, Latanoprost (0.005%)
- Where
- Nigeria
- Volunteers
- 138 people
- Sponsor
- Lagos State Health Service Commission