Clinical trials: Intraocular Lens
Aphakia
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System
The purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
- Trial name
- NCT02418871
- Testing
- FluidVision AIOL, Cataract surgery
- Where
- 5 sites in Hungary, South Africa
- Volunteers
- 53 people
- Sponsor
- PowerVision
Cataract, Presbyopia
Clinical Trial With PRECIZON Presbyopic
The purpose of this clinical trial is to evaluate the effectiveness of the PRECIZON Presbyopic.
- Trial name
- NCT02409771
- Testing
- PRECIZON Presbyopic
- Where
- 6 sites in Belgium, Germany and 3 more
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Cataract
Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens
This is a study to assess the spectacle independence and quality of vision of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04124952
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightTrust Eye Institute
Aphakia, Postcataract
Yamani Technique Versus Proline Mesh for Intraocular Lens Scleral Fixation in Aphakia
The study aims to describe a new method of sulcus fixation of intraocular lenses (IOLs) using a prolene mesh and to compare its outcomes with Yamani technique.
- Trial name
- NCT06363448
- Testing
- Yamani Technique versus Prolene Mesh for Intraocular Lens Scleral Fixation in Aphakia
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Cataracts, Visual Acuity Reduced Transiently
The Incidence of Glistenings in the 2017 Intraocular Lenses Made by Alcon and Abbott Medical Optics
The purpose of this study is to seek academic/non-industry research funding support to independently investigate the incidence and density of lens glistenings in cataract patients who are implanted with the latest generations of…
- Conditions
- Cataracts, Visual Acuity Reduced Transiently, Loss of Visual Contrast Sensitivity, Functional Visual Loss
- Trial name
- NCT03409185
- Testing
- Alcon 1 piece SA60AT lens, AMO 1-piece AABOO lens
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Toronto
Cataract
Cell Ongrowth and Biocompatibility Study of Two Different (Hydrophobic Acrylic) Intraocular Lenses: IOL XY1 vs. IOL XY1A
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT06708806
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataract
Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surgery With PCIOL.
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iStent/Hydrus/Goniotomy…
- Trial name
- DEXTENZA (NCT05372315)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iworks Laser and Vision Center
Refractive Error, Corneal Implantation
Piggyback Sulcoflex Toric IOL for Correcting Refractive Error Following Corneal Transplantation
A prospective study to evaluate the safety and efficacy of a piggyback sulcoflex toric intraocular lens in pseudophakic patients for correcting refractive errors following corneal transplantation
- Conditions
- Refractive Error, Corneal Implantation, Intraocular Lens Implantation
- Trial name
- NCT01718184
- Testing
- toric intraocular lens implantation, Sulcoflex intraocular lens implantation
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
To Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual Acuity
Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three
The purpose of the study is to determine whether implantation of a multifocal IOL with a modified addition at lens plane(Restor +3) results in better intermediate visual acuity with similar performance at distance and near…
- Trial name
- NCT01027533
- Testing
- Implantation of a multifocal Intraocular lens
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cataract
Patients Outcomes of a Monofocal Intraocular Lens Designed for Monovision
The rationale for this observational study of a CE-marked lens is to prospectively assess the performance, safety, and patient satisfaction in a group of subjects undergoing cataract surgery with bilateral implantation of the…
- Trial name
- NCT06528678
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 51 people
- Sponsor
- Clinica Baviera
Cataract, Pseudophakia
Retrospective, Non-interventional Clinical Investigation of the Safety and Performance of 640AD Monofocal Intraocular Lens
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOL) is indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Trial name
- NCT06578910
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Medicontur Medical Engineering Ltd
Age Related Cataracts
Posterior Capsule Opafication of Different Hydrophobic Acrylic Intraocular Lenses: Vivinex iSert P261 vs.Clareon IOL
On the day of surgery, the first eye to be operated is randomised to receive a Vivinex , HOYA Surgical Optics GmbH or an Clareon, Alcon, Fort Worth, Texas. The second eye to be operated receives the other IOL type.
- Trial name
- Clarinex (NCT04369482)
- Testing
- Alcon Clareon, Hoya Vivinex
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cataract
Clinical Outcome After Implantation of Two Different Multifocal Toric IOLs: Liberty (677MTY) and PanOptix®
This study is to compare the rotational stability, visual outcome and patient satisfaction after implantation with either Liberty 677MTY, a multifocal diffractive-refractive IOL based on EPS technology manufactured by Medicontur…
- Trial name
- NCT05895396
- Where
- Hungary
- Volunteers
- 35 people
- Sponsor
- Medicontur Medical Engineering Ltd
Astigmatism, High Myopia
Comparison Between TICL and ICL+AK for High Myopic Astigmatism
To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.
- Trial name
- NCT03202485
- Testing
- Toric Implantable Collamer Lens, ICL + Astigmatic keratotomy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Dry Eye Syndromes
Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL
This is a prospective, open-label, single-center, randomized, head-to-head, investigator-sponsored clinical study. It aims to investigate the vision recovery and patient comfort in borderline/mild dry eye disease patients…
- Trial name
- ENHANCE (NCT04863742)
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sight Medical Doctors PLLC
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cataract, Presbyopia
Non-comparative Study to Assess the Visual Performances and Safety of a Progressive Multifocal Intraocular Lens
This is an interventional, non-controlled, multicenter international trial with a prospective design on one cohort of patients.
- Trial name
- PSM15 (NCT02838004)
- Testing
- IOL MINI WELL READY
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- SIFI SpA
Presbyopia, IOL, Cataract
Evaluation of the Visual Acuity Curves of an Enhanced Monofocal Intraocular Lens
The primary objective of this study is to evaluate postoperative visual acuity curves in pseudophakic patients following unilateral or bilateral implantation of the enhanced monofocal TECNIS Eyhance IOL, using the DDARTVC.
- Trial name
- IOL-VAC (NCT07439835)
- Testing
- Phacoemulsification with enhanced monofocal IOLs
- Where
- Greece
- Volunteers
- 62 people
- Sponsor
- Democritus University of Thrace