Clinical trials: Internal Hemorrhoids
Internal Haemorrhoids
Auricular Indwelling Needles Added to Diosmin/Hesperidin for Grade I-II Internal Hemorrhoids With Heat-Toxin Syndrome
The goal of this clinical trial is to learn if adding small ear needles to a standard oral medicine can ease symptoms in adults with early-stage internal hemorrhoids (swollen blood vessels inside the anus, grade I-II) who also…
- Trial name
- AIN-MPFF (NCT07899229)
- Testing
- Auricular Indwelling Needles, Micronized Purified Flavonoid Fraction (Diosmin and Hesperidin)
- Volunteers
- 64 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Internal Piles Sclerotherapy, Internal Hemorrhoids
Evaluation of Polidocanol Foam Sclerotherapy in Symptomatic Internal Hemorrhoids: A Prospective Study
To evaluate the efficacy, durability, safety, and clinical/endoscopic outcomes of standardized 3% polidocanol foam sclerotherapy in patients with symptomatic grade II-III internal hemorrhoids over a 12-month follow-up period.
- Trial name
- NCT07866248
- Testing
- Standardized 3% Polidocanol Foam Sclerotherapy
- Volunteers
- 130 people
- Sponsor
- Radwa Hussein Mohammed Hasanen
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Lateral Internal Sphincterotomy, Hemorrhoidectomy
Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids
This study aims to compare the lateral internal sphincterotomy versus no lateral internal sphincterotomy during hemorrhoidectomy in the management of patients with hemorrhoids.
- Conditions
- Lateral Internal Sphincterotomy, Hemorrhoidectomy, Hemorrhoids
- Trial name
- NCT06884774
- Testing
- Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Hemorrhoids Third Degree, Internal Hemorrhoids
HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids
This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy…
- Conditions
- Hemorrhoids Third Degree, Internal Hemorrhoids, Mixed Hemorrhoids
- Trial name
- HELO (NCT07333040)
- Testing
- Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), Ferguson Hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhoidal Bleeding, Hemorrhoids, Internal
Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS
The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL).
- Conditions
- Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
- Trial name
- STRATOS (NCT07559630)
- Testing
- Hemorrhoidal Artery Embolization, Rubber Band Ligation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Jessica K. Stewart, MD
Hemorrhoidal Disease, Internal Hemorrhoids
Clinical Outcomes After Laser Hemorrhoidoplasty
This single-center prospective observational study aims to evaluate clinical outcomes, postoperative pain scores, complications, and patient satisfaction in adults undergoing laser hemorrhoidoplasty for symptomatic internal…
- Trial name
- LHP (NCT07520734)
- Testing
- Laser Hemorrhoidoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain.
- Conditions
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- Trial name
- LHP-MMH (NCT07678814)
- Testing
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allama Iqbal Medical College
Internal Hemorrhoid
Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids
This study will assess how effective and safe rectal artery embolization works to treat symptomatic bleeding predominant internal hemorrhoids.
- Trial name
- HEMBO-1 (NCT06106269)
- Testing
- Rectal Artery Embolization
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Hemorrhoid, Hemorrhoids
Endoscopic Injection Sclerotherapy Versus Endoscopic Band Ligation for Grade I-III Internal Hemorrhoids
This study is a prospective, multicentre, and randomized-controlled clinical study.The researchers wanted to explore the optimal treatment regimen for soft hemorrhoid within I-Ⅲ degrees by evaluating and comparing the…
- Conditions
- Hemorrhoid, Hemorrhoids, Hemorrhoids Internal, Hemorrhoid Prolapse
- Trial name
- NCT05089500
- Testing
- Endoscopic injection sclerotherapy, Endoscopic Band Ligation
- Where
- 2 sites in China
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Hemorrhoid, Internal Hemorrhoids
Prospective HemorrhoIdaL EmboliSation (PILES) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults…
- Conditions
- Hemorrhoid, Internal Hemorrhoids, Hemorrhoid Bleeding, Hemorrhoidal Bleeding
- Trial name
- PILES (NCT07635784)
- Testing
- Hemorrhoid Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Haemorrhoids, Internal Haemorrhoids
Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease
Surgical treatment of grade II/III internal haemorrhoidal disease is indicated in the case of medical and/or instrumental treatment failure.
- Conditions
- Haemorrhoids, Internal Haemorrhoids, Grade II/III Haemorrhoids
- Trial name
- RADIOLIGA (NCT06170736)
- Testing
- Doppler-Guided Haemorrhoidal Artery Ligation, Radiofrequency ablation
- Where
- 18 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Internal Hemorrhoids, Postoperative Pain After Endoscopic Rubber Band Ligation
Nitroglycerin Ointment for Pain Relief After Endoscopic Hemorrhoid Band Ligation
This study is designed to evaluate whether nitroglycerin ointment can reduce pain after endoscopic rubber band ligation for internal hemorrhoids.
- Trial name
- NCT07391501
- Testing
- Nitroglycerin Ointment
- Volunteers
- 68 people
- Sponsor
- Ying Zhu
Internal Hemorrhoids, HAE
Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)
Hemorrhoidal artery embolization (HAE) is a novel treatment for symptomatic internal hemorrhoids. HAE involves the deliberate blockage (embolization) of enlarged rectal or hemorrhoidal arteries leading to reduction of abnormal…
- Trial name
- HELIOS (NCT07179601)
- Testing
- Hemorrhoidal artery embolization
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Grade II Internal Hemorrhoids With Bleeding
A Phase III Clinical Trial Evaluating the Efficacy and Safety of TriThien Duoc Capsules in Grade II Internal Haemorrhoids Patients With Bleeding Compared to Diosmin.
A Phase III, randomized, double-blind, placebo-controlled clinical trial has been conducted to evaluate the efficacy and safety of Trĩ Thiên Dược capsules in people with grade II internal hemorrhoids with bleeding.
- Trial name
- NCT07369635
- Testing
- Intervention Group: Tri Thien Duoc Capsules, Control group (diosmin)
- Where
- Vietnam
- Volunteers
- 172 people
- Sponsor
- Hanoi Medical University
Hemorrhoid, Cough
Cough and Hemorrhoids
The aim of the study is to investigate the relationship between hemorrhoids and cough by assessing the symptoms, duration, and severity of cough in patients who will present to the general surgery outpatient clinic of Muğla…
- Conditions
- Hemorrhoid, Cough, Cough Duration, Cough Frequency
- Trial name
- NCT06878209
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Muğla Sıtkı Koçman University
Hemorrhoids, Hemorrhoids, Internal
SCI-Pex Study - Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids
The SCI-Pex study is a multicenter, prospective, non-controlled investigation on PexyEazy®, a new device for treatment of hemorrhoids based on the mucopexy method.
- Conditions
- Hemorrhoids, Hemorrhoids, Internal, Suture; Complications, Infection or Inflammation, Rectal Diseases
- Trial name
- SCI-Pex (NCT05782010)
- Testing
- PexyEazy
- Where
- 3 sites in Sweden
- Volunteers
- 35 people
- Sponsor
- Developeration AB
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Internal Hemorrhoid, Rectal Prolapse
CAES for Internal Hemorrhoids and Rectal Prolapse
Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy.
- Trial name
- NCT04169152
- Testing
- Cap-assisted endoscopic sclerotherapy
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Faming Zhang
Internal Hemorrhoid
Recurrence Rate of Minimally Invasive Endoscopic Treatment of Internal Hemorrhoids
2.1 Main objective: To observe the short-term and long-term recurrence rates of various endoscopic minimally invasive treatment methods for internal hemorrhoids and different time points of endoscopic minimally invasive treatment…
- Trial name
- NCT06250140
- Testing
- Tie up device
- Volunteers
- 900 people
- Sponsor
- Shenzhen Hospital of Southern Medical University