Hemorrhoids Second DegreeLHP-MMHNCT07678814
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
A study testing Laser Hemorrhoidoplasty and Milligan Morgan Hemorrhoidectomy in people with Hemorrhoids Second Degree and Hemorrhoids Third Degree, run by Allama Iqbal Medical College at 1 site in Pakistan.
Trial summary
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain. Laser Hemorrhoidoplasty has emerged as a minimally invasive alternative. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- What is being tested?
- Laser Hemorrhoidoplasty and Milligan Morgan Hemorrhoidectomy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 96 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Sep 2025to 31 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥18 years Grade II hemorrhoids Grade III hemorrhoids Both genders
Who cannot join
- Rectal prolapse Anal fissure Anorectal malignancy Pregnancy or lactating mothers
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids: A Randomized Controlled Trial
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain. Laser Hemorrhoidoplasty has emerged as a minimally invasive alternative. This randomized controlled trial compares postoperative pain, patient satisfaction, and hospital stay between Laser Hemorrhoidoplasty and conventional hemorrhoidectomy in patients with Grade II and Grade III hemorrhoids.
Read the detailed description
This single-center randomized controlled trial was conducted in the Department of Surgery, Jinnah Hospital Lahore. Ninety-six patients diagnosed with Grade II or Grade III hemorrhoids were randomized into two equal groups.
Group A underwent Laser Hemorrhoidoplasty.
Group B underwent conventional Milligan Morgan Hemorrhoidectomy.
Patients were followed postoperatively for pain assessment using the Visual Analogue Scale (VAS), hospital stay, and patient satisfaction using a structured Likert-scale questionnaire.
- Being tested
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Keywords
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy, Randomized Controlled Trial, Postoperative Pain, Patient Satisfaction
- Medical subject headings
- Pain, Postoperative, Patient Satisfaction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Laser HemorrhoidoplastyProcedure or surgery
Patients randomized to the intervention group underwent Laser Hemorrhoidoplasty under spinal anesthesia. A diode laser probe was introduced into the hemorrhoidal tissue through a small mucosal entry point under direct visualization using an anoscope. Controlled laser energy was delivered submucosally to achieve coagulation, shrinkage, and fixation of the hemorrhoidal cushions while preserving the surrounding anoderm and mucosa. The procedure was performed according to standard surgical protocols with the aim of reducing postoperative pain, bleeding, and recovery time.
Milligan Morgan HemorrhoidectomyProcedure or surgery
Patients randomized to the control group underwent conventional open Milligan Morgan Hemorrhoidectomy under spinal anesthesia. The hemorrhoidal pedicles were identified, ligated, and excised using standard surgical techniques. The wounds were left open with preservation of mucocutaneous bridges between excision sites. Hemostasis was achieved as required. Patients received routine postoperative care and follow-up according to institutional protocols.
| Study group | Role | What they receive |
|---|---|---|
| Laser Hemorrhoidoplasty | Experimental | Patients underwent Laser Hemorrhoidoplasty using diode laser energy applied to hemorrhoidal tissue. Receives: Procedure: Laser Hemorrhoidoplasty |
| Milligan Morgan Hemorrhoidectomy | Active comparator | Patients underwent conventional open Milligan Morgan Hemorrhoidectomy. Receives: Procedure: Milligan Morgan Hemorrhoidectomy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain
Pain measured using Visual Analogue Scale (VAS).
Measured: Post Operative period: (6) Six Hourly in first 48 Hours, at 1 week post operative period & at 1 month post operatively.
Patient Satisfaction
Patient satisfaction assessed using Likert-scale questionnaire.
Measured: 1 month postoperative
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2026
- Study start1 Sep 2025
- Primary completion28 Feb 2026
- Study completion31 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hemorrhoids Second DegreeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 96 participants (actual)
Sponsor and investigators
- Lead sponsor
- Allama Iqbal Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr. Muhammad, Allama Iqbal Medical College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07678814
- Sponsor's protocol ID
- ERB166 / 9 / 11-06-2024/S1 ERB
- Acronym
- LHP-MMH
- Status last verified
- Jun 2026
- First submitted
- 25 Jun 2026
- Last updated
- 1 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data collected during the study will not be made publicly available. Data will remain confidential and will be retained by the investigators in accordance with institutional policies and ethical approval requirements.
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07678814
- Acronym / sponsor ID
- LHP-MMH / ERB166 / 9 / 11-06-2024/S1 ERB
- Keywords
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy, Randomized Controlled Trial, Postoperative Pain, Patient Satisfaction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 96 participants (actual)
- Lead sponsor
- Allama Iqbal Medical CollegeUniversity, hospital or other
- Study start
- 1 Sep 2025 (actual)
- Primary completion
- 28 Feb 2026 (actual)
- Study completion
- 31 Mar 2026 (actual)
- First posted
- 1 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain. Laser Hemorrhoidoplasty has emerged as a minimally invasive alternative. This randomized controlled trial compares postoperative pain, patient satisfaction, and hospital stay between Laser Hemorrhoidoplasty and conventional hemorrhoidectomy in patients with Grade II and Grade III hemorrhoids.
Detailed description
This single-center randomized controlled trial was conducted in the Department of Surgery, Jinnah Hospital Lahore. Ninety-six patients diagnosed with Grade II or Grade III hemorrhoids were randomized into two equal groups.
Group A underwent Laser Hemorrhoidoplasty.
Group B underwent conventional Milligan Morgan Hemorrhoidectomy.
Patients were followed postoperatively for pain assessment using the Visual Analogue Scale (VAS), hospital stay, and patient satisfaction using a structured Likert-scale questionnaire.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Laser Hemorrhoidoplasty | Experimental | Procedure: Laser HemorrhoidoplastyPatients underwent Laser Hemorrhoidoplasty using diode laser energy applied to hemorrhoidal tissue. |
| Milligan Morgan Hemorrhoidectomy | Active comparator | Procedure: Milligan Morgan HemorrhoidectomyPatients underwent conventional open Milligan Morgan Hemorrhoidectomy. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Age ≥18 years Grade II hemorrhoids Grade III hemorrhoids Both genders
Key exclusion criteria (1 listed)
- Rectal prolapse Anal fissure Anorectal malignancy Pregnancy or lactating mothers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Laser HemorrhoidoplastyPatients randomized to the intervention group underwent Laser Hemorrhoidoplasty under spinal anesthesia. A diode laser probe was introduced into the hemorrhoidal tissue through a small mucosal entry point under direct visualization using an anoscope. Controlled laser energy was delivered submucosally to achieve coagulation, shrinkage, and fixation of the hemorrhoidal cushions while preserving the surrounding anoderm and mucosa. The procedure was performed according to standard surgical protocols with the aim of reducing postoperative pain, bleeding, and recovery time. | Procedure or surgery | Laser Hemorrhoidoplasty |
| Milligan Morgan HemorrhoidectomyPatients randomized to the control group underwent conventional open Milligan Morgan Hemorrhoidectomy under spinal anesthesia. The hemorrhoidal pedicles were identified, ligated, and excised using standard surgical techniques. The wounds were left open with preservation of mucocutaneous bridges between excision sites. Hemostasis was achieved as required. Patients received routine postoperative care and follow-up according to institutional protocols. | Procedure or surgery | Milligan Morgan Hemorrhoidectomy |
Primary outcome
Postoperative Pain
Time frame: Post Operative period: (6) Six Hourly in first 48 Hours, at 1 week post operative period & at 1 month post operatively.
Pain measured using Visual Analogue Scale (VAS).
Patient Satisfaction
Time frame: 1 month postoperative
Patient satisfaction assessed using Likert-scale questionnaire.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2026.
- Individual participant dataSharing planned: No. Individual participant data collected during the study will not be made publicly available. Data will remain confidential and will be retained by the investigators in accordance with institutional policies and ethical approval requirements.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Laser Hemorrhoidoplasty and Milligan Morgan Hemorrhoidectomy in people with Hemorrhoids Second Degree and Hemorrhoids Third Degree, run by Allama Iqbal Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain (time frame: Post Operative period: (6) Six Hourly in first 48 Hours, at 1 week post operative period & at 1 month post operatively.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2026.