Clinical trials: Incomplete Miscarriage
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Incomplete Abortion
Sublingual Misoprostol Versus Standard Surgical Care for the Treatment of Incomplete Abortion in Nigeria
Women diagnosed with incomplete abortion in this health facility will be randomized to receive one of the following regimens: 400 mcg sublingual misoprostol in one dose or standard surgical treatment (MVA).
- Trial name
- NCT01539408
- Testing
- Misoprostol, surgery Manual vacuum aspiration (MVA)
- Where
- 2 sites in Nigeria
- Volunteers
- 90 people
- Sponsor
- Gynuity Health Projects
Abortion, Missed
Comparison of Two Different Drug Regimens for Medical Treatment of Early Pregnancy Loss
The purpose of this study is to compare the safety and efficacy of a combination of two drugs (mifepristone and misoprostol) to only one of these drugs (misoprostol) in medical management of missed miscarriage up to 13+6 weeks of…
- Trial name
- NCT05124314
- Testing
- Mifepristone, Oral, 200 Mg, Misoprostol Pill
- Where
- Croatia
- Volunteers
- 220 people
- Sponsor
- Clinical Hospital Merkur
Retained Products After Miscarriage
The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC
Pregnancy tissue can be found remaining in the womb in up to 20% of women following a miscarriage. These "retained products of conception" (RPOC), which are diagnosed by transvaginal ultrasound, can cause prolonged bleeding…
- Trial name
- HYMMN (NCT04751500)
- Testing
- Outpatient hysteroscopy, Expectant management, Medical management
- Where
- United Kingdom
- Volunteers
- 149 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Silent Miscarriage
Letrozole Versus Mifepristone and Misoprostol in Silent Miscarriage
Management of first trimester silent miscarriage can be by expectant, medical or surgical management. Surgical management by suction evacuation is associated with surgical risks (including risks to the womb that can affect…
- Trial name
- NCT06733727
- Testing
- Letrozole, Mifepristone
- Volunteers
- 884 people
- Sponsor
- The University of Hong Kong
Hydatidiform Mole (Diagnosis), Abortion, Spontaneous
The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles
This is a prospective observational study assessing which ultrasound findings are best at excluding a molar pregnancy in first trimester miscarriage.
- Conditions
- Hydatidiform Mole (Diagnosis), Abortion, Spontaneous, Missed Abortion, Incomplete Miscarriage
- Trial name
- NCT05516810
- Where
- 2 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- King's College Hospital NHS Trust
Missed Abortion, Incomplete Abortion
The Role of Uterine Artery Doppler Parameters in the Management of Retained Products of Conception.
During the recent decades the need for surgical evacuation of the uterus in early miscarriages and incomplete miscarriages has been questioned.
- Conditions
- Missed Abortion, Incomplete Abortion, Uterine Gestational Residua, Uterine Artery Doppler
- Trial name
- NCT01775917
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Carmel Medical Center
Miscarriage in First Trimester, Missed Miscarriage
Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage
The goal of this clinical trial is to learn whether adding the medicine letrozole to Misoprostol helps women have a complete abortion more often than using Misoprostol alone for the treatment of missed miscarriage (when a…
- Trial name
- NCT07160855
- Testing
- Misoprostol (given vaginally), Letrozole 5 mg
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- Nishtar Medical University
Incomplete Miscarriage
Effectiveness of Hysteroscopy in the Treatment of Intrauterine Trophoblastic Retentions
The purpose of this study of is to compare subsequent fertility rates between hysteroscopy and aspirative curettage in the surgical treatment of incomplete spontaneous abortion
- Trial name
- HY-PER (NCT02201732)
- Testing
- Hysteroscopy, Curettage
- Where
- France
- Volunteers
- 577 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Incomplete Abortion
Misoprostol Treatment of Incomplete Abortion by Midwives and Physicians in Uganda
Uganda is one of the countries with highest fertility rate in the world, 6.7 children per women. It is estimated that 56 percent of all pregnancies are unintended and the contraceptive prevalence rate in Uganda is 23 percent.
- Trial name
- NCT01743508
- Testing
- Misoprostol treatment by midwife
- Where
- Uganda
- Volunteers
- 731 people
- Sponsor
- Karolinska Institutet
Miscarriage
Misoprostol for Management of Women With an Incomplete Miscarriage
Miscarriage is defined as the spontaneous loss of a pregnancy before 24 weeks gestation, that is, before fetal viability. The clinical signs of miscarriage are usually vaginal bleeding associated with abdominal pain and cramping.
- Trial name
- NCT05088720
- Testing
- misoprostol 800 µg, misoprostol 400 µg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Incomplete Abortion, Intrauterine Contraception
Ideal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Abortion
Background: Unintended pregnancies continue to cause a public health threat in Low and Middle Income countries yet with restrictive abortion laws.
- Conditions
- Incomplete Abortion, Intrauterine Contraception, Misoprostol
- Trial name
- PAIC (NCT05343546)
- Testing
- Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
- Where
- Uganda
- Volunteers
- 2,076 people
- Sponsor
- Makerere University
Missed Abortion, Medical; Abortion, Fetus
Gemeprost Versus Dinoprostone in First Trimester Miscarriages
Comparison between gemeprost and dinoprostone to evacuate first trimester miscarriages.
- Conditions
- Missed Abortion, Medical; Abortion, Fetus, Incomplete Abortion
- Trial name
- NCT05342467
- Testing
- Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg
- Where
- 2 sites in Malaysia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Effect of Drug
Analgesia From Conscious Sedation Versus Paracervical Block for Manual Vacuum Aspiration
Miscarriage is one of the major causes of early pregnancy losses. Incomplete miscarriage is a major cause of maternal morbidity and mortality.
- Trial name
- NCT06539143
- Testing
- Lidocaine
- Where
- Nigeria
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Incomplete Abortion
Treatment of Incomplete Abortion With 600 Mcg Oral Misoprostol Compared to Standard Surgical Treatment
This study aims to compare the efficacy, side effects profile and acceptability of a single dose of 600mcg misoprostol taken orally compared to standard surgical treatment as per local protocols for the treatment of incomplete…
- Trial name
- NCT00674232
- Testing
- 600 mcg misoprostol, Surgical treatment
- Where
- 3 sites in Ecuador, Venezuela
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Incomplete
Misoprostol for the Treatment of Incomplete Abortion
This randomized study will examine the efficacy, safety and acceptability of misoprostol for treatment of incomplete abortion. Women diagnosed with incomplete abortion will be randomized to receive one of the following regimens…
- Trial name
- NCT00670761
- Testing
- misoprostol, MVA
- Where
- 6 sites in Burkina Faso, Madagascar and 3 more
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Nonviable Pregnancy
The Effect of Topical Lidocaine on Pain Scores During Manual Vacuum Aspiration for Nonviable Pregnancies
When a patient requires a manual vacuum aspiration (MVA), whether for an undesired pregnancy, missed abortion, or other nonviable pregnancy, she is undergoing an emotional experience.
- Trial name
- NCT01708330
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Bridgeport Hospital
Incomplete Abortion
400mcg Sublingual Misoprostol as First Line Treatment
Women presenting with incomplete abortion and eligible for treatment with misoprostol were offered 400mcg sublingual misoprostol for treatment.
- Trial name
- NCT01939457
- Testing
- Misoprostol
- Where
- Senegal
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects