Clinical trials: Immune Development
Nutrient Gap in Children, Pediatric Health and Well-Being
A Clinical Trial to Evaluate the Effects of a Children's Daily Multivitamin on Perceived Growth, Immune Health, Energy, and Focus in Children
This is a single-group, open-label, fully decentralized (virtual) clinical trial evaluating the effects of the Hiya Kids Daily Multivitamin on parent/caregiver-perceived growth and development, immune health, daily energy, focus…
- Conditions
- Nutrient Gap in Children, Pediatric Health and Well-Being, Immune Health, Growth and Development
- Trial name
- NCT07893626
- Testing
- Hiya Kids Daily Multivitamin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hiya Health
Hereditary Transmission, Immune Development
Maternal Grandmothers in the Born in Guangzhou Cohort Study
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China.
- Conditions
- Hereditary Transmission, Immune Development, Childhood Obesity, Host and Microbiome
- Trial name
- MGBIG (NCT03633162)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Host and Microbiome, Pregnancy Outcomes
Human Genes and Microbiota in Early Life
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life…
- Conditions
- Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders
- Trial name
- HuGME (NCT06926166)
- Testing
- No intervention
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Intrauterine Hyperglycemia, Pregnancy Outcomes
The Born in Guangzhou Cohort Study (BIGCS)
The Born in Guangzhou Cohort Study (BIGCS) was established to investigate the short- and long-term effects of exposure in early life on health consequences in Guangzhou, China.
- Conditions
- Intrauterine Hyperglycemia, Pregnancy Outcomes, Neurodevelopment, Immune Development
- Trial name
- BIGCS (NCT02526901)
- Testing
- No intervention
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Twin Diseases, Immune Development
Twins Born in Guangzhou
The 2-BIG is a twin birth cohort study located in Guangzhou, China.Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin Diseases, Immune Development, Childhood Obesity, Host and Microbiome
- Trial name
- 2-BIG (NCT03331133)
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Preterm Birth, Neurodevelopment
Preterm Birth Cohort Study in Guangzhou
The Preterm Birth Cohort Study in Guangzhou (PBCSG) aims to explore the impact of genetic and environmental factors including life styles on preterm birth, to examine the interaction effect between these factors, and to follow up…
- Conditions
- Preterm Birth, Neurodevelopment, Immune Development, Host and Microbiome
- Trial name
- PBCSG (NCT03668327)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Gestational Diabetes Mellitus, Pregnancy Outcome
GDM and Its Consequences in Mothers and Offsprings
Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term…
- Conditions
- Gestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development
- Trial name
- GDMCMO (NCT04529889)
- Where
- China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Growth, Vitamin D Supplementation
Next-generation Effects of Vitamin D Supplementation in Pregnancy
Vitamin D deficiency is common among pregnant women, despite daily vitamin D supplements. This study aims to investigate if maternal vitamin D intake of 90 vs 10 µg affects the overall health, growth, and immune system of the…
- Conditions
- Growth, Vitamin D Supplementation, Immune System Diseases, Child Development
- Trial name
- NCT05616117
- Testing
- Intrauterine 90µg D-vitamin, Intrauterine 10µg D-vitamin
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health