Clinical trials: Hysterectomy, Benign Uterine Diseases
Uterine Diseases
Hysterectomy by Transabdominal Laparoscopy or NOTES
Objective: To randomly compare hysterectomy by vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) versus laparoscopy uterus in women with benign gynecological pathology.
- Trial name
- HALON (NCT02631837)
- Testing
- vNOTES hysterectomy, LSC hysterectomy
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Uterine Neoplasms
ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Hysterectomy.
The study assesses the impact on quality of care of implementing the ERAS (Enhanced Recovery After Surgery) protocol for hysterectomy of benign or malignant tumors of the uterus in the network of public hospitals in the Regione…
- Trial name
- ERAS-Gyneco (NCT04063072)
- Testing
- ERAS protocol
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Ospedale Regina Montis Regalis
Uterine Diseases
Laparoscopic Versus Vaginal Cuff Closure During LH in Benign Gynecological Lesions
To compare vaginal cuff closure via Bakay purse string with vaginal cuff closure via vaginal route with continuous locked suturing after total laparoscopic hysterectomy for benign lesions.
- Trial name
- NCT05823935
- Testing
- Bakay purse string, Cuff closure via vaginal route group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Menorrhagia, Metrorrhagia
Minimally Invasive Benign Hysterectomy
A randomised controlled trial comparing hysterectomy by minimally invasive surgical methods; robotic hysterectomy versus vaginal hysterectomy or traditional laparoscopic hysterectomy; outcome and cost analyses.
- Conditions
- Menorrhagia, Metrorrhagia, Uterine Fibroids, Cervical Dysplasia
- Trial name
- NCT01865929
- Testing
- Robotic hysterectomy, Vaginal or laparoscopic hysterectomy
- Where
- Sweden
- Volunteers
- 124 people
- Sponsor
- Region Skane
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hysterectomy, Benign Uterine Diseases
vNOTES Versus Vaginal Hysterectomy for Benign Gynecologic Indications
This randomized non-inferiority trial aims to compare early and late postoperative outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy and vaginal hysterectomy in women undergoing…
- Trial name
- NCT07846670
- Testing
- vNOTES Hysterectomy, Vaginal Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hatice Nur ÖZGEN
Benign Uterine Disease
LESS-TLH Versus LESS-LAVH
During the last 2 decades, several studies have tried to define the best surgical approach to hysterectomy for benign uterine diseases1.
- Trial name
- NCT01861067
- Testing
- LESS-TLH, LESS-LAVH
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- CHA University
Hysterectomy, Benign Uterine Diseases, Abdominal Pain (AP)
Comparison of Postoperative Analgesic Efficacy of TAP Block and TFP Block in Patients Undergoing Abdominal Hysterectomy
Total abdominal hysterectomy is one of the most commonly performed surgeries in women and is known to cause significant pain in especially early postoperative period.
- Trial name
- NCT06853782
- Testing
- High Frequency Linear Probe (GE Logic e R7 Ultrasonography Device, USA)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Hacettepe University
Hysterectomy, Benign Uterine Diseases
Systematic Approach for Cold Knife Morcellation of Large Uterus in Total Laparoscopic Hysterectomy
Following the completion of the TLH and before vault closure, the uterus is flipped upside down to resemble a flask and is grasped by the assistant from the cervix.
- Trial name
- NCT07330102
- Testing
- Morcellation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital