Clinical trials: Hysterectomy, Benign Uterine Diseases
Benign Uterine Diseases
Feasibility and Benefit of Laparoscopic Hysterectomy With Less Than 3 Millimeter Diameter's Instruments in Current Practice
Hysterectomy for benign uterine disease is often intended to young perimenopausal patients. Currently laparoscopic hysterectomy is commonly used in this indication.
- Trial name
- NCT02367703
- Testing
- laparoscopic hysterectomy
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Clermont-Ferrand
Benign Uterine Disease
Impact of Opportunistic Salpingectomy on Ovarian Reserve in Patients Undergoing Laparoscopic Hysterectomy
Recently, many gynecologic oncologists proposed that surgeons should consider opportunistic salpingectomy to prevent ovarian cancer for all patients undergoing hysterectomy for benign disease.
- Trial name
- NCT01893086
- Testing
- LH alone, LH with opportunistic salpingectomy
- Where
- 3 sites in South Korea
- Volunteers
- 68 people
- Sponsor
- CHA University
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Genital Diseases, Female, Hysterotomy; Affecting Fetus
Effect of Salpingectomy During Conservative Hysterectomy
The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian…
- Conditions
- Genital Diseases, Female, Hysterotomy; Affecting Fetus, Leiomyomata Uteri, Adenomyosis, Endometriosis
- Trial name
- SALPINGOVA (NCT01628432)
- Testing
- conservative hysterectomy I, Conservative hysterectomy II
- Where
- 7 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Tours
Uterine Diseases
Hysterectomy by Transabdominal Laparoscopy or NOTES
Objective: To randomly compare hysterectomy by vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) versus laparoscopy uterus in women with benign gynecological pathology.
- Trial name
- HALON (NCT02631837)
- Testing
- vNOTES hysterectomy, LSC hysterectomy
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Uterine Diseases
Laparoscopic Versus Vaginal Cuff Closure During LH in Benign Gynecological Lesions
To compare vaginal cuff closure via Bakay purse string with vaginal cuff closure via vaginal route with continuous locked suturing after total laparoscopic hysterectomy for benign lesions.
- Trial name
- NCT05823935
- Testing
- Bakay purse string, Cuff closure via vaginal route group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Hysterectomy, Benign Uterine Diseases
Effect of Posterior Colpotomy First Technique on the Vaginal Length During Total Abdominal Hysterectomy
the same surgeon performed all of the procedures using the same method. A lower midline or Pfannestiel incision is the first step in the complete abdominal hysterectomy procedure. They clamp, cut, and ligate the top pedicles.
- Trial name
- NCT07308197
- Testing
- Abdominal hysterectomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Benign or Preinvasive Uterine Disease
Study of Laparoendoscopic Single Site Hysterectomy in Benign and Preinvasive Uterine Disease
To compare the efficacy between single-port and three-port laparoscopic assisted vaginal hysterectomy in patients with benign or preinvasive uterine disease
- Trial name
- NCT01679548
- Testing
- Single-port LAVH, Three-port LAVH
- Where
- South Korea
- Volunteers
- 424 people
- Sponsor
- Asan Medical Center
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Adenomyosis, Quality of Life
Quality of Life After Hysterectomy (AdenoQOL)
Adenomyosis is a disease where ectopic endometrial-like glands affect the muscular wall of the uterus. About 70% of women affected by adenomyosis suffer from dysmenorrhea and menorrhagia.
- Trial name
- NCT04791033
- Testing
- Hysterectomy
- Where
- Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Benign Uterine Disease
Study on Bladder and Sexual Function Change After Simple Hysterectomy
To evaluate the incidence and pattern of bladder symptoms and sexual function change occuring after simple hysterectomy and to analyze the influence of bladder symptoms and sexual function change on quality of life of patients.
- Trial name
- NCT01683890
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Asan Medical Center
Uterine Fibroids, Uterine Leiomyoma
Vaginal vs. Laparoscopic Hysterectomy
Hysterectomy for benign indication is one of the most common surgical procedures in women. Numerous reviews and guidelines recommend the vaginal approach for benign hysterectomy, but the proportion of laparoscopic (and robotic)…
- Conditions
- Uterine Fibroids, Uterine Leiomyoma, Abnormal Uterine Bleeding, Unspecified
- Trial name
- NCT02059954
- Testing
- Hysterectomy
- Where
- 3 sites in Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Graz
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Benign Disease of the Uterus
Feasibility of a Trial of Laparoscopic Hysterectomy Versus Laparoscopic Sub-Total Hysterectomy
Observational studies suggest faster recovery and quicker return to normal activities following laparoscopic supracervical hysterectomy (LSH which involves removal of the body of the womb but conservation of the neck of the womb…
- Trial name
- LaHoST (NCT01825915)
- Testing
- Laparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Medway NHS Foundation Trust
Hysterectomy, Hysterectomy, Benign Uterine Diseases
VNOTES and Vaginal Hysterectomy for Benign Indications
This study aimed to compare the surgical outcomes of Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) and conventional vaginal hysterectomy (VH) for benign gynecological conditions.
- Conditions
- Hysterectomy, Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
- Trial name
- NCT06776718
- Testing
- vNOTES, vaginal hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Hysterectomy, Benign Uterine Diseases
Robotic Minimally Invasive Benign Hysterectomy Post-market Clinical Study With the DEXTER Robotic System
The purpose of this post-market, observational study is to collect real-world data under anticipated conditions of use that demonstrates that the device performs as intended (accurate, precise control of surgical instruments) in…
- Trial name
- MAGENTA (NCT07746531)
- Testing
- benign hysterectomy
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Distalmotion SA
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Uterine Bleeding Disorders, Benign Uterine Conditions
Comparison of BiCision® Versus UltraCision® During Laparoscopic Supracervical Hysterectomy (LASH)
The aim of the study is the evaluation of the efficiency and safety of the new, CE-certified thermofu-sion and dissection instrument BiCision® in comparison with the long established Ultracision® Har-monic Scalpel(Ethicon)during…
- Conditions
- Uterine Bleeding Disorders, Benign Uterine Conditions, Focus: Comparison of Two Instruments
- Trial name
- NCT01752725
- Testing
- BiCision®, Ultracision® Har-monic Scalpel(Ethicon)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Tuebingen
Endometrial Cancer
The Effects of the Endocrine System on Endometrial Cancer
Endometrial cancer usually begins in the endometrium, which is the tissue lining of the uterus. Endometrial cancer is the most commonly diagnosed gynaecological malignancy in Australia.
- Trial name
- Ghrelin (NCT01075386)
- Where
- Australia
- Volunteers
- 75 people
- Sponsor
- Queensland Centre for Gynaecological Cancer