Clinical trials: Hypospadias
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Postoperative Pain, Hypospadias
Effect of Intravenous Dexamethasone With Pudendal Nerve Block on Postoperative Pain in Pediatric Hypospadias Repair
This study aims to determine if intravenous Dexamethasone combined with a pudendal nerve block is able to prolong postoperative analgesia in children undergoing hypospadias repair.
- Trial name
- NCT03902249
- Testing
- Dexamethasone
- Volunteers
- 70 people
- Sponsor
- Dr Sonia ben khalifa (PhD)
Hypospadias
Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair
From September 2014 to March 2015, 57 consecutive patients with hypospadias who are candidate for surgery will be enrolled in this randomized clinical trial.
- Trial name
- NCT02752308
- Testing
- Bupivacaine, General anesthesia, Dilute epinephrine injection
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Hypospadias, Caudal Block
Multifidus Plane Block Versus Caudal Block for Hypospadias
This study aims to evaluate the safety and efficacy of ultrasound-guided sacral multifidus plane block and compare its analgesic effect to ultrasound-guided caudal block in pediatric patients undergoing hypospadias surgery under…
- Trial name
- NCT06561269
- Testing
- Multifidus plane block, caudal block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Anesthesia, General
The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in Children
The purpose of this study is to determine whether Propofol and Sevoflurane affect the oxidative stress and apoptosis status in children undergoing hypospadias repair surgery.
- Trial name
- NCT02711280
- Testing
- Sevoflurane, Propofol
- Where
- China
- Volunteers
- 47 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Postoperative Pain, Analgesia
Comparison of Erector Spinae Plane Block and Penile Block in Hypospadias Surgery
In this study, we aimed to compare ultrasound-guided sacral erector spinae plane block and dorsal penile block on postoperative analgesic effect in hypospadias surgery.
- Trial name
- NCT04866368
- Testing
- The ultrasound-guided Sacral Erector spinae plane block, The dorsal penile block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Hypospadias Repair
TIP Repair of Distal Penile Hypospadias Using Rapidly Absorbable Braided Vs Slowly Absorbable Monofilament Sutures
Objective: To study the effect of tubularizing the urethral plate in DPH in children using 2 different absorbable suture materials, rapidly absorbable, braided 6/0 Vicryl and slowly absorbable monofilament 6/0 Polydioxanone, on…
- Trial name
- NCT06413901
- Testing
- TIP
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Cairo University
Hypospadias, Hypospadias, Coronal
Caudal Anesthesia Versus Local Anesthesia in Hypospadias
Hypospadias is among the most common congenital genital malformations in boys and is typically treated through surgical intervention.
- Conditions
- Hypospadias, Hypospadias, Coronal, Caudal Anesthesia, Children
- Trial name
- NCT06417060
- Testing
- Caudal block anesthesia, Dorsal penile block anesthesia
- Where
- 3 sites in North Macedonia, Russia and 1 more
- Volunteers
- 200 people
- Sponsor
- Necmi Kadıoğlu Hospital
Distal Hypospadias, Hypospadias
Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias
Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis.
- Trial name
- FTIP-RCT (NCT07319780)
- Testing
- Fibrin-Enhanced TIP Urethroplasty, Grafted TIP Urethroplasty
- Where
- 2 sites in Indonesia, Uzbekistan
- Volunteers
- 100 people
- Sponsor
- National Children's Medical Center, Uzbekistan
Hypospadias
Modified Second Layer Repair for Distal Penile Hypospadias
to evaluate a modification to snodgrass technique in second layer closure of distal penile hypospadias
- Trial name
- NCT05253456
- Testing
- Derma -Dartos Flap for second layer closure
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Hypospadias
Identification of Hypospadias Parameters Using Digital Photography and Artificial Intelligence
The goal of this observational study is to develop and validate a digital pattern recognition system based on artificial neural network to determine various parameters in hypospadias.
- Trial name
- ASHOKA (NCT05569863)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hypospadias
Long-term Assesment of Patients Operated for Hypospadias in Their Childhood : Urinary, Aesthetical, Sexual and Psycho-social Consequences
The purpose of this study is to assess the long term urinary, sexual, cosmetic and psycho-social outcomes of adult patients operated for hypospadias during childhood
- Trial name
- SAHARA (NCT05319782)
- Testing
- Urethral stenosis assesment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hypospadias
Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP)
The purpose of this study is to determine the efficacy and safety of tubularized incised plate urethroplasty versus foreskin graft tubularized incised plate urethroplasty in primary hypospadias.
- Trial name
- FGTIP-TIP (NCT02497963)
- Testing
- Foreskin Graft-Tubularized Incised Plate, Tubularized Incised Plate
- Volunteers
- 68 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Distal Hypospadias Repair
Topography Guided Repair Versus TIP for Distal Hypospadias
This study compares two surgical techniques used to repair distal hypospadias in children: topography-guided repair (TGR), a newer approach, and tubularized incised plate (TIP) repair, a commonly used standard technique.
- Trial name
- DPH repair (NCT07832760)
- Testing
- Topography Guided Repair, Tubularized Incised Plate Repair
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Alexandria University
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Hypospadias Repair Surgery
Urethral Mobilisation Versus Mathieu Technique for Repair of Distal Hypospadias
The aim of this research is to compare the surgical outcomes of urethral mobilization and the Mathieu technique in treating distal penile hypospadias.
- Trial name
- NCT06705699
- Testing
- Urethral mobilisation, Mathieu
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypospadias Repair, Pediatric Anesthesia
Caudal vs Dorsal Penile Nerve Block for Postoperative Analgesia in Children Undergoing Hypospadias Repair (CaD-DPNB)
This prospective, randomized clinical trial conducted at Ain Shams University Hospitals evaluated the analgesic efficacy of dorsal penile nerve block versus caudal epidural block in 30 male children undergoing primary hypospadias…
- Conditions
- Hypospadias Repair, Pediatric Anesthesia, Postoperative Analgesia
- Trial name
- CaD-DPNB (NCT07306806)
- Testing
- Caudal epidural block, Dorsal Penile nerve Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Postoperative Analgesia, S-ketamine
Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Caudal analgesia with ropivacaine is commonly used in sub-umbilical pediatric surgery. However, increasing the dosage of ropivacaine has not been found to prolong the action significantly while complications will be serious.
- Conditions
- Postoperative Analgesia, S-ketamine, Pediatrics, Caudal Block
- Trial name
- NCT05922605
- Testing
- S-ketamine & Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Tao Zhang
Postoperative Pain
Pudendal vs Caudal Block for Pediatric Penile Surgery
The study will compare recovery profile in children receiving pudendal blocks vs caudal analgesia for ambulatory circumcision or hypospadias repair in children between 6 months and 2 years.
- Trial name
- NCT04840654
- Testing
- Caudal Block, Pudendal Block
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
Pain, Comfort
Virtual Reality Intervention in Children After Hypospadias Surgery
The aim of this study is to examine the effect of virtual reality glasses use on pain, comfort, and psychosocial symptoms in children after hypospadias surgery.
- Conditions
- Pain, Comfort, Psychosocial Symptoms
- Trial name
- NCT07752680
- Testing
- Virtual reality headset, routine clinical practice
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medipol University Hospital