Clinical trials: Hospital Mortality
Polytrauma Patients
Predictive Value of Revised Trauma Score(RTS)and Glasgow Coma Scale (GCS)of Mortality in Patients with Multiple Trauma.
This study aims to assess the efficacy of RTS and GCS in predicating the mortality among multiple trauma patients admitted to emergency departments at Assiut university hospital.Which score is better in predicting mortality in…
- Trial name
- NCT06737874
- Volunteers
- 100 people
- Sponsor
- Assiut University
Motor Activity, Muscle Strength
Critical Care Observation of Motor Activity (COMA) and SICU Outcomes
In the surgical intensive care unit (SICU), goals of critical care are often discussed in long-term ventilated patients around the time of extubation.
- Conditions
- Motor Activity, Muscle Strength, Muscle Weakness
- Trial name
- COMA (NCT02994641)
- Testing
- COMA Score Assessment
- Where
- United States
- Volunteers
- 761 people
- Sponsor
- Massachusetts General Hospital
ICU Delirium
Modified Hospital Elder Life Program at Intensive Care Unit
Delirium, a form of acute brain dysfunction, occurs in up to 81% of patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- mHelp@ICU (NCT06054828)
- Testing
- mHELP@ICU
- Where
- Taiwan
- Volunteers
- 266 people
- Sponsor
- National Taiwan University Hospital
Cardiac Surgery Under Extra Corporeal Circulation
Postoperative Morbidity and Mortality After Cardiac Surgery
The local database results from a joint initiative of anesthesic, cardiology and cardiac surgery departements.Its purpose is to record in an exhaustive fashion all the interventions of cardiac surgery performed under…
- Trial name
- Cardiobase (NCT03393169)
- Where
- France
- Volunteers
- 12,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Disease
In-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have been shown to improve cardiovascular outcomes when added to conventional statin therapy.
- Trial name
- NCT05184530
- Testing
- Evolocumab 140 MG/ML
- Volunteers
- 7,556 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Life Quality, Hospital Mortality
Effect of Nutritional Support and Early Rehabilitation on Sepsis
Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a…
- Trial name
- NUSPOTER (NCT05781971)
- Testing
- high protein, rehabilitation, standard protein
- Volunteers
- 1,600 people
- Sponsor
- Jinling Hospital, China
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
COVID-19 Pandemic, Vitamin D Deficiency
COVID-19 and Vitamin D: Length of Hospital Stay and Mortality
The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition.
- Trial name
- NCT05221983
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Yuksek Ihtisas University
In-hospital Mortality, Non-COVID Deaths
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
This study aims to perform a retrospective cohort study of administrative health data to understand how care delivery performance varies across US hospitals post-COVID-19 pandemic compared to the pre-pandemic performance.
- Conditions
- In-hospital Mortality, Non-COVID Deaths, Surge
- Trial name
- NCT06651645
- Testing
- COVID-19 Surge
- Where
- United States
- Volunteers
- 30,000,000 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Complications
Surgical Outcome and Multimodal Monitoring - SOMM
This study is designed to test if measuring the depth of anaesthesia, brain tissue oxygenation and haemodynamic parameters and specially designed interventions according to the measurements can improve the outcome of high risk…
- Trial name
- SOMM (NCT02293473)
- Testing
- LiDCO Rapid, BIS-Bispectral Index Monitor, INVOS-Cerebral Oxygenation Monitor
- Where
- Slovenia
- Volunteers
- 89 people
- Sponsor
- University Medical Centre Ljubljana
Sepsis, Antimicrobial Resistance (AMR)
Implementation of a Sepsis Chart and Its Effects on Mortality Rate in Indonesian Primary Referral Hospitals
The goal of this observational study is to evaluate the effectiveness of implementing Koran Sepsis, or sepsis chart, a paper-based order set designed to guide the implementation of the One-hour Sepsis Bundle, in improving…
- Trial name
- NCT07843277
- Testing
- Sepsis chart (koran sepsis), Usual care
- Where
- 2 sites in Indonesia
- Volunteers
- 304 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Carbapenem Resistant Bacteria Infection
European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems
Among antibiotic-resistant organisms, the Gram-negative bacteria are now the most important challenge because of the rapid worldwide spread of mechanisms conferring resistance to multiple drugs.
- Trial name
- EURECA (NCT02709408)
- Where
- 50 sites in Albania, Bulgaria and 9 more
- Volunteers
- 2,515 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Gastrointestinal Cancer, Frailty
Preoperative Frailty and Postoperative Outcomes in Older Patients Undergoing Surgery for Gastrointestinal Cancer
This prospective observational cohort study will evaluate whether preoperative frailty, assessed using the Fried Frailty Index and the Clinical Frailty Scale, is associated with postoperative outcomes in patients aged 60 years or…
- Trial name
- NCT07815392
- Testing
- Fried Frailty Index, Clinical Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Van Training and Research Hospital
Myocardial Infarction
Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction
This is a multicenter multidisciplinary study designed to investigate patient, provider, and system-related factors that are associated with the quality and safety of initial management for suspected ST-segment elevation…
- Trial name
- STEMI-Qual (NCT02788344)
- Testing
- Daily practice care for patients with suspected of STEMI
- Where
- France
- Volunteers
- 6,920 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Gastric Cancer
Annual Hospital Volume and and Short-term Postoperative Outcomes After Gastric Cancer Resection
The effect of centralisation measures on the operative outcomes after gastric cancer resection in Switzerland has not been highlighted yet.
- Trial name
- NCT07072429
- Testing
- Gastric cancer resection
- Where
- Switzerland
- Volunteers
- 3,112 people
- Sponsor
- Cantonal Hospital of St. Gallen
Liver Neoplasms, Hepatobiliary Diseases
Outcomes After Liver and Biliary Resection at a High-Volume Center
The goal of this observational study is to evaluate clinical and oncologic outcomes in adult patients undergoing liver and/or biliary resection for benign and malignant diseases.
- Conditions
- Liver Neoplasms, Hepatobiliary Diseases, Cholangiocarcinoma, Hepatocellular Carcinoma
- Trial name
- BILIVER (NCT07556835)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda USL Toscana Centro
Hyperglycemia, Critically Ill Patients
Impact of 2 Blood Glucose Levels on Hospital Mortality in Patients Admitted in ICU
During hospitalization in the intensive care unit (ICU), the occurrence of a blood glucose imbalance is frequent and associated with increased mortality.
- Trial name
- INSUREA (NCT00591071)
- Testing
- Strict glycemic control, Conventional glycemic control
- Where
- 2 sites in France
- Volunteers
- 440 people
- Sponsor
- Poissy-Saint Germain Hospital
Medical Device
Technical Capabilities of the "SMART ANGEL Intra-hospital" System 's Connected Medical Device (CMD)
Post-operative mortality in case of scheduled surgery is 3% in France (Lancet 2013) mainly due to cardiovascular or respiratory complications, by decompensation of pre-existing pathologies.
- Trial name
- SMART-METRO (NCT04668807)
- Testing
- Connected Medical Device, Traditional transmission system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Social Isolation, Frailty
Community-based Pro-Active Monitoring Program (CAMP) and Older Adults
Background: According to World Health Organization the world population is rapidly aging, and this impacts Health and Social Services.
- Trial name
- CAMP-80 (NCT04785664)
- Testing
- Community-based pro-Active Monitoring Program
- Where
- Italy
- Volunteers
- 1,185 people
- Sponsor
- University of Rome Tor Vergata